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Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

Clinical pharmacology and therapeutics, 2015-09, Vol.98 (3), p.266-287

2015

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The complexities of hepatic drug transport: current knowledge and emerging concepts

Pharmaceutical research, 2004-05, Vol.21 (5), p.719-735

2004

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Qualitative evaluation of postdoctoral trainee and faculty advisor experiences within a research-intensive school of pharmacy

BMC medical education, 2022-09, Vol.22 (1), p.1-691, Article 691

2022

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Pharmacokinetic and Pharmacodynamic Implications of P-glycoprotein Modulation

Pharmacotherapy, 2001-07, Vol.21 (7), p.778-796

2001

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Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.916-932

2018

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Membrane transporters in drug development

Nature reviews. Drug discovery, 2010-03, Vol.9 (3), p.215-236

2010

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A Perspective on Efflux Transport Proteins in the Liver

Clinical pharmacology and therapeutics, 2012-11, Vol.92 (5), p.599-612

2012

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.126-141

2013

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Contribution of Morphine-6-Glucuronide to Antinociception following Intravenous Administration of Morphine to Healthy Volunteers

Journal of clinical pharmacology, 2002-05, Vol.42 (5), p.569-576

2002

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P-glycoprotein-mediated transport of morphine in brain capillary endothelial cells

Biochemical pharmacology, 1999-09, Vol.58 (6), p.951-957

1999

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Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis

Clinical pharmacology and therapeutics, 2015-04, Vol.97 (4), p.419-427

2015

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Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.388-394

2005

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Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

European journal of pharmaceutical sciences, 2006-04, Vol.27 (5), p.447-486

2006

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Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats

Drug metabolism and disposition, 2006-04, Vol.34 (4), p.556-562

2006

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P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide

Pharmaceutical research, 2004-07, Vol.21 (7), p.1294-1302

2004

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Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver

The Journal of pharmacology and experimental therapeutics, 2003-02, Vol.304 (2), p.801-809

2003

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Population Pharmacokinetics of Morphine in Patients With Nonalcoholic Steatohepatitis (NASH) and Healthy Adults

CPT: pharmacometrics and systems pharmacology, 2017-05, Vol.6 (5), p.331-339

2017

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Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats

Drug metabolism and disposition, 1999-06, Vol.27 (6), p.637

1999

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Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid–Mediated DILI

CPT: pharmacometrics and systems pharmacology, 2014-07, Vol.3 (7), p.1-8

2014

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Role of Glycosylation in Trafficking of Mrp2 in Sandwich-Cultured Rat Hepatocytes

Molecular pharmacology, 2005-04, Vol.67 (4), p.1334-1341

2005

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Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital

Drug metabolism and disposition, 2002-08, Vol.30 (8), p.918-923

2002

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In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development : Transporters in Drug Development and Clinical Pharmacology

Clinical pharmacology and therapeutics, 2013, Vol.94 (1), p.95-112

2013

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Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes

Biochemical pharmacology, 2006-05, Vol.71 (10), p.1520-1529

2006

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Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice

Drug metabolism and disposition, 2006-04, Vol.34 (4), p.718-723

2006

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In vitro mechanisms of probenecid-associated alterations in acetaminophen glucuronide hepatic disposition

Drug metabolism and disposition, 1997-09, Vol.25 (9), p.1017

1997

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Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

The complexities of hepatic drug transport: current knowledge and emerging concepts

Qualitative evaluation of postdoctoral trainee and faculty advisor experiences within a research-intensive school of pharmacy

Pharmacokinetic and Pharmacodynamic Implications of P-glycoprotein Modulation

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Membrane transporters in drug development

A Perspective on Efflux Transport Proteins in the Liver

Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Contribution of Morphine-6-Glucuronide to Antinociception following Intravenous Administration of Morphine to Healthy Volunteers

P-glycoprotein-mediated transport of morphine in brain capillary endothelial cells

Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis

Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats

P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide

Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver

Population Pharmacokinetics of Morphine in Patients With Nonalcoholic Steatohepatitis (NASH) and Healthy Adults

Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats

Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid–Mediated DILI

Role of Glycosylation in Trafficking of Mrp2 in Sandwich-Cultured Rat Hepatocytes

Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital

In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development : Transporters in Drug Development and Clinical Pharmacology

Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes

Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice

In vitro mechanisms of probenecid-associated alterations in acetaminophen glucuronide hepatic disposition

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