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Regulatory Challenges, Reimbursement, and Risk-Benefit Assessment

Clinical pharmacology and therapeutics, 2010-08, Vol.88 (2), p.153-154

Breckenridge, A

2010

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The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA -Mutant Breast Cancer Brain Metastases

Clinical cancer research, 2019-06, Vol.25 (11), p.3374-3383

2019

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NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors

Nature medicine, 2012-12, Vol.18 (12), p.1827-1834

2012

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A new glacial varve chronology along the southern Laurentide Ice Sheet that spans the Younger Dryas–Holocene boundary

Geology (Boulder), 2021-03, Vol.49 (3), p.283-288

2021

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M2 Macrophages promote IL-33 expression, ILC2 expansion and mucous metaplasia in response to early life rhinovirus infections

Frontiers in immunology, 2022-08, Vol.13, p.952509-952509

2022

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Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function

Journal of molecular and cellular cardiology, 2014-09, Vol.74 (100), p.340-352

2014

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Adaptive licensing and facilitated regulatory pathways: A survey of stakeholder perceptions

Clinical pharmacology and therapeutics, 2015-11, Vol.98 (5), p.477-479

2015

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Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

BMJ, 2004-07, Vol.329 (7456), p.15-19

2004

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Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism

PLoS biology, 2013-09, Vol.11 (9), p.e1001666-e1001666

2013

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Hypoxia at the heart of sudden infant death syndrome?

Pediatric research, 2013-10, Vol.74 (4), p.375-379

2013

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Insulin-like growth factor binding protein (IGFBP6) is a cross-species tendon marker

European Cells and Materials, 2019-09, Vol.38, p.123-136

2019

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Regulatory Consequences of “Brexit” for the Development of Medicinal Products

Clinical pharmacology and therapeutics, 2017-08, Vol.102 (2), p.183-184

2017

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The Challenges of Orphan Drugs and Orphan Diseases: Real and Imagined

Clinical pharmacology and therapeutics, 2012-08, Vol.92 (2), p.151-153

2012

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The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon

Journal of Virology, 2012-04, Vol.86 (8), p.4566-4577

2012

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Report on the current status of the use of real‐world data (RWD) and real‐world evidence (RWE) in drug development and regulation

British journal of clinical pharmacology, 2019-09, Vol.85 (9), p.1874-1877

2019

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Overcoming the legal and regulatory barriers to drug repurposing

Nature reviews. Drug discovery, 2019-01, Vol.18 (1), p.1-2

2019

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Post-marketing Strategies for Medicines

Clinical pharmacology and therapeutics, 2008-01, Vol.83 (1), p.24-25

Breckenridge, A

2008

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Regional‐Scale Landscape Response to an Extreme Precipitation Event From Repeat Lidar and Object‐Based Image Analysis

Earth and space science (Hoboken, N.J.), 2022-12, Vol.9 (12), p.n/a

2022

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A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome

Disease models & mechanisms, 2013-03, Vol.6 (2), p.503-507

2013

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The Future of Drug Safety

Clinical pharmacology and therapeutics, 2007-02, Vol.81 (2), p.161-163

Breckenridge, A

2007

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Regulatory Review: How Do Agencies Ensure the Quality of Decision Making?

Clinical pharmacology and therapeutics, 2013-09, Vol.94 (3), p.305-308

2013

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TGF-β signaling and its targeting for glioma treatment

American journal of cancer research, 2015-01, Vol.5 (3), p.945-955

2015

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Advancing the Science of Medicines Regulation: The Role of the 21st-Century Medicines Regulator

Clinical pharmacology and therapeutics, 2012-10, Vol.92 (4), p.486-493

2012

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Risk Sharing and Payment by Results

Clinical pharmacology and therapeutics, 2008-05, Vol.83 (5), p.666-667

2008

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European Perspective on Risk Management and Drug Safety

Clinical pharmacology and therapeutics, 2011-05, Vol.89 (5), p.650-654

2011

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Regulatory Challenges, Reimbursement, and Risk-Benefit Assessment

The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA -Mutant Breast Cancer Brain Metastases

NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors

A new glacial varve chronology along the southern Laurentide Ice Sheet that spans the Younger Dryas–Holocene boundary

M2 Macrophages promote IL-33 expression, ILC2 expansion and mucous metaplasia in response to early life rhinovirus infections

Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function

Adaptive licensing and facilitated regulatory pathways: A survey of stakeholder perceptions

Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism

Hypoxia at the heart of sudden infant death syndrome?

Insulin-like growth factor binding protein (IGFBP6) is a cross-species tendon marker

Regulatory Consequences of “Brexit” for the Development of Medicinal Products

The Challenges of Orphan Drugs and Orphan Diseases: Real and Imagined

The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon

Report on the current status of the use of real‐world data (RWD) and real‐world evidence (RWE) in drug development and regulation

Overcoming the legal and regulatory barriers to drug repurposing

Post-marketing Strategies for Medicines

Regional‐Scale Landscape Response to an Extreme Precipitation Event From Repeat Lidar and Object‐Based Image Analysis

A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome

The Future of Drug Safety

Regulatory Review: How Do Agencies Ensure the Quality of Decision Making?

TGF-β signaling and its targeting for glioma treatment

Advancing the Science of Medicines Regulation: The Role of the 21st-Century Medicines Regulator

Risk Sharing and Payment by Results

European Perspective on Risk Management and Drug Safety

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