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Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms

Applied and Environmental Microbiology, 2000-06, Vol.66 (6), p.2541-2547

2000

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The Guanacastepenes: A Highly Diverse Family of Secondary Metabolites Produced by an Endophytic Fungus

Journal of the American Chemical Society, 2001-10, Vol.123 (40), p.9900-9901

2001

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Biological Activity of Guanacastepene, a Novel Diterpenoid Antibiotic Produced by an Unidentified Fungus CR115

The Journal of Antibiotics, 2000/03/25, Vol.53(3), pp.256-261

2000

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Isolation of Antibiotics Turbomycin A and B from a Metagenomic Library of Soil Microbial DNA

Applied and Environmental Microbiology, 2002-09, Vol.68 (9), p.4301-4306

2002

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Design and Synthesis of a Series of Potent and Orally Bioavailable Noncovalent Thrombin Inhibitors That Utilize Nonbasic Groups in the P1 Position

Journal of medicinal chemistry, 1998-08, Vol.41 (17), p.3210-3219

1998

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Design of Novel, Potent, Noncovalent Inhibitors of Thrombin with Nonbasic P-1 Substructures: Rapid Structure−Activity Studies by Solid-Phase Synthesis

Journal of medicinal chemistry, 1998-03, Vol.41 (7), p.1011-1013

1998

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New Natural Product Families from an Environmental DNA (eDNA) Gene Cluster

Journal of the American Chemical Society, 2002-08, Vol.124 (34), p.9968-9969

2002

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Cloning and Heterologous Expression of a Natural Product Biosynthetic Gene Cluster from eDNA

Organic letters, 2001-06, Vol.3 (13), p.1981-1984

2001

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Long-Chain N-Acyl Amino Acid Antibiotics Isolated from Heterologously Expressed Environmental DNA

Journal of the American Chemical Society, 2000-12, Vol.122 (51), p.12903-12904

2000

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Palmitoylputrescine, an Antibiotic Isolated from the Heterologous Expression of DNA Extracted from Bromeliad Tank Water

Journal of natural products (Washington, D.C.), 2004-08, Vol.67 (8), p.1283-1286

2004

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Pantocin B, an Antibiotic from Erwinia herbicola Discovered by Heterologous Expression of Cloned Genes

Journal of the American Chemical Society, 1999-12, Vol.121 (50), p.11912-11913

1999

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The Cytosporones, New Octaketide Antibiotics Isolated from an Endophytic Fungus

Organic letters, 2000-12, Vol.2 (25), p.4043-4046

2000

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HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

Biochemical and biophysical research communications, 1988-10, Vol.156 (1), p.297-303

1988

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Amino Acid Sequence of Homologous Rat Atrial Peptides: Natriuretic Activity of Native and Synthetic Forms

Proceedings of the National Academy of Sciences - PNAS, 1984-05, Vol.81 (9), p.2640-2644

1984

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Inhibition of thrombin by peptides containing Lysyl-alpha-keto carbonyl derivatives

Thrombosis and haemostasis, 1995-10, Vol.74 (4), p.1107-1112

1995

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Chemical Synthesis and Enzymatic Activity of a 99-Residue Peptide with a Sequence Proposed for the Human Immunodeficiency Virus Protease

Proceedings of the National Academy of Sciences - PNAS, 1988-10, Vol.85 (19), p.7129-7133

1988

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Cytoskyrins A and B, New BIA Active Bisanthraquinones Isolated from an Endophytic Fungus

Organic letters, 2000-12, Vol.2 (25), p.4047-4049

2000

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Antithrombotic effects of MK-0852, a platelet fibrinogen receptor antagonist, in canine models of thrombosis

The Journal of pharmacology and experimental therapeutics, 1993-09, Vol.266 (3), p.1501

1993

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CR377, a New Pentaketide Antifungal Agent Isolated from an Endophytic Fungus

Journal of natural products (Washington, D.C.), 2000-10, Vol.63 (10), p.1447-1448

2000

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Metagenomic approaches for the discovery of new bioactive natural products

Planta medica, 2014, Vol.80 (10)

Brady, SF

2014

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A super active cyclic hexapeptide analog of somatostatin

Life sciences (1973), 1984-01, Vol.34 (14), p.1371-1378

1984

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The solution conformation Ac-Pen-Arg-Gly-Asp-Cys-OH, a potent fibrinogen receptor antagonist

Biopolymers, 1993-08, Vol.33 (8), p.1287-1297

1993

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NMR and molecular modeling characterization of RGD containing peptides

International Journal of Peptide and Protein Research, 1992-01, Vol.39 (1), p.63-76

1992

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ZmaR, a Novel and Widespread Antibiotic Resistance Determinant That Acetylates Zwittermicin A

Journal of Bacteriology, 1999-09, Vol.181 (17), p.5455-5460

1999

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Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms

The Guanacastepenes: A Highly Diverse Family of Secondary Metabolites Produced by an Endophytic Fungus

Biological Activity of Guanacastepene, a Novel Diterpenoid Antibiotic Produced by an Unidentified Fungus CR115

Isolation of Antibiotics Turbomycin A and B from a Metagenomic Library of Soil Microbial DNA

Design and Synthesis of a Series of Potent and Orally Bioavailable Noncovalent Thrombin Inhibitors That Utilize Nonbasic Groups in the P1 Position

Design of Novel, Potent, Noncovalent Inhibitors of Thrombin with Nonbasic P-1 Substructures: Rapid Structure−Activity Studies by Solid-Phase Synthesis

New Natural Product Families from an Environmental DNA (eDNA) Gene Cluster

Cloning and Heterologous Expression of a Natural Product Biosynthetic Gene Cluster from eDNA

Long-Chain N-Acyl Amino Acid Antibiotics Isolated from Heterologously Expressed Environmental DNA

Palmitoylputrescine, an Antibiotic Isolated from the Heterologous Expression of DNA Extracted from Bromeliad Tank Water

Pantocin B, an Antibiotic from Erwinia herbicola Discovered by Heterologous Expression of Cloned Genes

Discovery and Development of the Novel Potent Orally Active Thrombin Inhibitor N-(9-Hydroxy-9-fluorenecarboxy)prolyl trans-4-Aminocyclohexylmethyl Amide (L-372,460): Coapplication of Structure-Based Design and Rapid Multiple Analogue Synthesis on Solid Support

The Cytosporones, New Octaketide Antibiotics Isolated from an Endophytic Fungus

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

Amino Acid Sequence of Homologous Rat Atrial Peptides: Natriuretic Activity of Native and Synthetic Forms

Inhibition of thrombin by peptides containing Lysyl-alpha-keto carbonyl derivatives

Chemical Synthesis and Enzymatic Activity of a 99-Residue Peptide with a Sequence Proposed for the Human Immunodeficiency Virus Protease

Cytoskyrins A and B, New BIA Active Bisanthraquinones Isolated from an Endophytic Fungus

Antithrombotic effects of MK-0852, a platelet fibrinogen receptor antagonist, in canine models of thrombosis

CR377, a New Pentaketide Antifungal Agent Isolated from an Endophytic Fungus

Metagenomic approaches for the discovery of new bioactive natural products

A super active cyclic hexapeptide analog of somatostatin

The solution conformation Ac-Pen-Arg-Gly-Asp-Cys-OH, a potent fibrinogen receptor antagonist

NMR and molecular modeling characterization of RGD containing peptides

ZmaR, a Novel and Widespread Antibiotic Resistance Determinant That Acetylates Zwittermicin A

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