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Estropause, Sex Hormones and Metal Homeostasis in the Mouse Brain

Frontiers in neurology, 2022-05, Vol.13, p.841822-841822

2022

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Endocrine Dyscrasia in the Etiology and Therapy of Alzheimer’s Disease

Journal of Alzheimer's disease, 2024-09, Vol.101 (3), p.705-713

2024

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Luteinizing hormone receptor mediates neuronal pregnenolone production via up‐regulation of steroidogenic acute regulatory protein expression

Journal of neurochemistry, 2007-03, Vol.100 (5), p.1329-1339

2007

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A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease Pathogenesis

Journal of Alzheimer's disease, 2015-01, Vol.47 (1), p.33-47

2015

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Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptors

Journal of neurochemistry, 2009-08, Vol.110 (3), p.1014-1027

2009

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The endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive disease

Hormones and behavior, 2015-11, Vol.76, p.63-80

2015

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A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks

Journal of Alzheimer's disease, 2015-01, Vol.44 (2), p.549-560

2015

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Not All Androgen Deprivation Therapies Are Created Equal: Leuprolide and the Decreased Risk of Developing Alzheimer's Disease

Journal of clinical oncology, 2016-08, Vol.34 (23), p.2800-2800

2016

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Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression

Journal of endocrinology, 2006-12, Vol.191 (3), p.651-663

2006

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Leuprolide acetate: a drug of diverse clinical applications

Expert opinion on investigational drugs, 2007-11, Vol.16 (11), p.1851-1863

2007

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Activin Receptor Signaling Regulates Prostatic Epithelial Cell Adhesion and Viability

Neoplasia (New York, N.Y.), 2009-04, Vol.11 (4), p.365,IN6-376,IN6

2009

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Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease

Molecular neurodegeneration, 2006-10, Vol.1 (1), p.14-14, Article 14

2006

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Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus Cholinesterase Inhibition to reduce Neurologic Decline in Alzheimer's

Contemporary clinical trials, 2021-08, Vol.107, p.106488-106488, Article 106488

2021

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Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data

Journal of Alzheimer's disease, 2018-01, Vol.63 (4), p.1269-1277

2018

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Reproductive hormones regulate the selective permeability of the blood-brain barrier

Biochimica et biophysica acta, 2008-06, Vol.1782 (6), p.401-407

2008

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Living and dying for sex: A theory of aging based on the modulation of cell cycle signaling by reproductive hormones

Gerontology (Basel), 2004-09, Vol.50 (5), p.265-290

2004

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Differential Processing of Amyloid-β Precursor Protein Directs Human Embryonic Stem Cell Proliferation and Differentiation into Neuronal Precursor Cells

The Journal of biological chemistry, 2009-08, Vol.284 (35), p.23806-23817

2009

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Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.20539-20545

2004

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A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele

BMC medical genetics, 2008-04, Vol.9 (1), p.37-37, Article 37

2008

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Increases in luteinizing hormone are associated with declines in cognitive performance

Molecular and cellular endocrinology, 2007-04, Vol.269 (1), p.107-111

2007

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Elevated Gonadotropin levels in Patients with Alzheimer disease

Mayo Clinic proceedings, 2001-09, Vol.76 (9), p.906-909

2001

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Does the degree of endocrine dyscrasia post-reproduction dictate post-reproductive lifespan? Lessons from semelparous and iteroparous species

GeroScience, 2017-02, Vol.39 (1), p.103-116

2017

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Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology

Journal of neuroscience research, 2002-11, Vol.70 (3), p.514-518

2002

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Dysregulation of the Hypothalamic-Pituitary-Gonadal Axis with Menopause and Andropause Promotes Neurodegenerative Senescence

Journal of neuropathology and experimental neurology, 2005-02, Vol.64 (2), p.93-103

2005

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The gonadotropin connection in Alzheimer's disease

Endocrine, 2005-04, Vol.26 (3), p.317-326

2005

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Estropause, Sex Hormones and Metal Homeostasis in the Mouse Brain

Endocrine Dyscrasia in the Etiology and Therapy of Alzheimer’s Disease

Luteinizing hormone receptor mediates neuronal pregnenolone production via up‐regulation of steroidogenic acute regulatory protein expression

A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease Pathogenesis

Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptors

The endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive disease

A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks

Not All Androgen Deprivation Therapies Are Created Equal: Leuprolide and the Decreased Risk of Developing Alzheimer's Disease

Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression

Leuprolide acetate: a drug of diverse clinical applications

Activin Receptor Signaling Regulates Prostatic Epithelial Cell Adhesion and Viability

Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease

Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus Cholinesterase Inhibition to reduce Neurologic Decline in Alzheimer's

Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data

Reproductive hormones regulate the selective permeability of the blood-brain barrier

Living and dying for sex: A theory of aging based on the modulation of cell cycle signaling by reproductive hormones

Differential Processing of Amyloid-β Precursor Protein Directs Human Embryonic Stem Cell Proliferation and Differentiation into Neuronal Precursor Cells

Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele

Increases in luteinizing hormone are associated with declines in cognitive performance

Elevated Gonadotropin levels in Patients with Alzheimer disease

Does the degree of endocrine dyscrasia post-reproduction dictate post-reproductive lifespan? Lessons from semelparous and iteroparous species

Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology

Dysregulation of the Hypothalamic-Pituitary-Gonadal Axis with Menopause and Andropause Promotes Neurodegenerative Senescence

The gonadotropin connection in Alzheimer's disease

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