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Targeting NLRP3 signaling by a novel-designed sulfonylurea compound for inhibition of microglial inflammation

Bioorganic & medicinal chemistry, 2022-03, Vol.58, p.116645-116645, Article 116645

2022

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Akt Pathway Inhibitors

Current topics in medicinal chemistry, 2020-01, Vol.20 (10), p.883-900

2020

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Development of Trypsin-Like Serine Protease Inhibitors as Therapeutic Agents: Opportunities, Challenges, and their Unique Structure-Based Rationales

Current topics in medicinal chemistry, 2016-05, Vol.16 (13), p.1506-1529

2016

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The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors

Molecules (Basel, Switzerland), 2022-01, Vol.27 (1), p.273

2022

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Recent advances in small molecule inhibitors of VEGFR and EGFR signaling pathways

Current topics in medicinal chemistry, 2011-06, Vol.11 (12), p.1571-1590

2011

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Setting the Record Straight: The Origin of the Pharmacophore Concept

Journal of chemical information and modeling, 2014-05, Vol.54 (5), p.1269-1283

2014

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Modulation of Enzyme Activity in the Kynurenine Pathway by Kynurenine Monooxygenase Inhibition

Frontiers in molecular biosciences, 2019-02, Vol.6, p.3-3

2019

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Managing the “Three Cs” of Academic Literature Authorship: Contributions, Credit, and Conflict

American journal of pharmaceutical education, 2023-05, Vol.87 (5), p.100009-100009, Article 100009

2023

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Pharmacophore modeling for ADME

Current topics in medicinal chemistry, 2013-06, Vol.13 (11), p.1327-1342

2013

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Akt Pathway Inhibition of the Solenopsin Analog, 2-Dodecylsulfanyl-1,-4,-5,-6-tetrahydropyrimidine

Anticancer research, 2019-10, Vol.39 (10), p.5329-5338

2019

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Methionine AminoPeptidase Type-2 Inhibitors Targeting Angiogenesis

Current topics in medicinal chemistry, 2016-05, Vol.16 (13), p.1478-1488

2016

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Towards a Better Understanding of Computational Models for Predicting DNA Methylation Effects at the Molecular Level

Current topics in medicinal chemistry, 2020-01, Vol.20 (10), p.901-909

2020

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A perspective on quantum mechanics calculations in ADMET predictions

Current topics in medicinal chemistry, 2013-06, Vol.13 (11), p.1257-1272

2013

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Design, synthesis, and screening of sulfonylurea-derived NLRP3 inflammasome inhibitors

Medicinal chemistry research, 2020-01, Vol.29 (1), p.126-135

2020

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Solenopsin A, a Venom Alkaloid from the Fire Ant Solenopsis invicta, Inhibits Quorum-Sensing Signaling in Pseudomonas aeruginosa

The Journal of infectious diseases, 2008-10, Vol.198 (8), p.1198-1201

2008

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Synthesis and biological evaluation of aromatic enones related to curcumin

Bioorganic & medicinal chemistry, 2005-06, Vol.13 (12), p.4007-4013

2005

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Selectivity, binding affinity, and ionization state of matrix metalloproteinase inhibitors

Current pharmaceutical design, 2013, Vol.19 (26), p.4701-4713

2013

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Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis

Blood, 2007-01, Vol.109 (2), p.560-565

2007

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Solenopsin A and analogs exhibit ceramide-like biological activity

Vascular cell, 2015-05, Vol.7 (1), p.5-5, Article 5

2015

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Advances in Drug Discovery for the Treatment of Cancer: Many Approaches, One Goal

Current topics in medicinal chemistry, 2016-01, Vol.16 (13), p.1411

2016

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Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4

Bioorganic & medicinal chemistry, 2018-03, Vol.26 (5), p.989-998

2018

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The adrenergic receptor antagonist carvedilol interacts with serotonin 2A receptors both in vitro and in vivo

Pharmacology, biochemistry and behavior, 2019-06, Vol.181, p.37-45

2019

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Discovery and biological activity of computer-assisted drug designed Akt pathway inhibitors

Bioorganic & medicinal chemistry letters, 2018-10, Vol.28 (19), p.3247-3250

2018

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Perspectives in Medicinal Chemistry: The Evolution of Medicinal Chemistry

Current topics in medicinal chemistry, 2016-04, Vol.16 (9), p.897-898

2016

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Substrate and inhibitor specificity of kynurenine monooxygenase from Cytophaga hutchinsonii

Bioorganic & medicinal chemistry letters, 2017-04, Vol.27 (8), p.1705-1708

2017

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Targeting NLRP3 signaling by a novel-designed sulfonylurea compound for inhibition of microglial inflammation

Akt Pathway Inhibitors

Development of Trypsin-Like Serine Protease Inhibitors as Therapeutic Agents: Opportunities, Challenges, and their Unique Structure-Based Rationales

The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors

Recent advances in small molecule inhibitors of VEGFR and EGFR signaling pathways

Setting the Record Straight: The Origin of the Pharmacophore Concept

Modulation of Enzyme Activity in the Kynurenine Pathway by Kynurenine Monooxygenase Inhibition

Managing the “Three Cs” of Academic Literature Authorship: Contributions, Credit, and Conflict

Pharmacophore modeling for ADME

Akt Pathway Inhibition of the Solenopsin Analog, 2-Dodecylsulfanyl-1,-4,-5,-6-tetrahydropyrimidine

Methionine AminoPeptidase Type-2 Inhibitors Targeting Angiogenesis

Towards a Better Understanding of Computational Models for Predicting DNA Methylation Effects at the Molecular Level

A perspective on quantum mechanics calculations in ADMET predictions

Design, synthesis, and screening of sulfonylurea-derived NLRP3 inflammasome inhibitors

Solenopsin A, a Venom Alkaloid from the Fire Ant Solenopsis invicta, Inhibits Quorum-Sensing Signaling in Pseudomonas aeruginosa

Synthesis and biological evaluation of aromatic enones related to curcumin

Selectivity, binding affinity, and ionization state of matrix metalloproteinase inhibitors

Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis

Solenopsin A and analogs exhibit ceramide-like biological activity

Advances in Drug Discovery for the Treatment of Cancer: Many Approaches, One Goal

Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4

The adrenergic receptor antagonist carvedilol interacts with serotonin 2A receptors both in vitro and in vivo

Discovery and biological activity of computer-assisted drug designed Akt pathway inhibitors

Perspectives in Medicinal Chemistry: The Evolution of Medicinal Chemistry

Substrate and inhibitor specificity of kynurenine monooxygenase from Cytophaga hutchinsonii

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