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Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

Nature communications, 2020-07, Vol.11 (1), p.3717-3717, Article 3717

2020

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Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

PLoS pathogens, 2020-12, Vol.16 (12), p.e1009100

2020

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Coronaviral RNA-methyltransferases: function, structure and inhibition

Nucleic acids research, 2022-01, Vol.50 (2), p.635

2022

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Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19

Journal of biomolecular structure & dynamics, 2021-09, Vol.39 (13), p.4582-4593

2021

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PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

The Journal of cell biology, 2018-05, Vol.217 (5), p.1797-1813

2018

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Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase

Nature communications, 2023-04, Vol.14 (1), p.2259-2259, Article 2259

2023

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Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

The Journal of cell biology, 2020-03, Vol.219 (3), p.1

2020

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Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy

Molecular cell, 2012-08, Vol.47 (3), p.339-348

2012

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Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses

Archives of virology, 2020-02, Vol.165 (2), p.355-366

2020

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High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses

Molecules (Basel, Switzerland), 2021-06, Vol.26 (13), p.3792

2021

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Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein

Angewandte Chemie (International ed.), 2021-04, Vol.60 (18), p.10172-10178

International ed. in English, 2021

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Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins

Scientific reports, 2019-01, Vol.9 (1), p.567-567, Article 567

2019

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Structural basis for iron piracy by pathogenic Neisseria

Nature (London), 2012-03, Vol.483 (7387), p.53-58

2012

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Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)

Journal of medicinal chemistry, 2021-06, Vol.64 (11), p.7596-7616

2021

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Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase

Viruses, 2021-08, Vol.13 (9), p.1722

2021

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Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (6), p.1901-1906

2012

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Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase

Antiviral research, 2017-01, Vol.137, p.131-133

2017

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Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus

Molecules (Basel, Switzerland), 2021-04, Vol.26 (9), p.2593

2021

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Phosphatidylinositol 4-kinases: Function, structure, and inhibition

Experimental cell research, 2015-10, Vol.337 (2), p.136-145

2015

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Structure and Function of the ESCRT-II-III Interface in Multivesicular Body Biogenesis

Developmental cell, 2009-08, Vol.17 (2), p.234-243

2009

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Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease

Frontiers in chemistry, 2021-01, Vol.8, p.595273-595273

2021

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Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

Scientific reports, 2016-03, Vol.6 (1), p.23641-23641, Article 23641

2016

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Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication

Viruses, 2021-08, Vol.13 (8), p.1585

2021

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Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D pol

Scientific reports, 2017-12, Vol.7 (1), p.17309-11, Article 17309

2017

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Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39

Journal of structural biology. X, 2024-12, Vol.10, p.100109, Article 100109

2024

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Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

Coronaviral RNA-methyltransferases: function, structure and inhibition

Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy

Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses

High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses

Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein

Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins

Structural basis for iron piracy by pathogenic Neisseria

Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)

Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase

Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit

Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase

Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus

Phosphatidylinositol 4-kinases: Function, structure, and inhibition

Structure and Function of the ESCRT-II-III Interface in Multivesicular Body Biogenesis

Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease

Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication

Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D pol

Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39

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