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Structure-Based Secondary Structure-Independent Approach To Design Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers

Journal of the American Chemical Society, 2006-12, Vol.128 (50), p.16190-16205

2006

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Improving Escherichia coli Alkaline Phosphatase Efficacy by Additional Mutations inside and outside the Catalytic Pocket

Chembiochem : a European journal of chemical biology, 2001-08, Vol.2 (7-8), p.517-523

2001

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Artificial Evolution of an Enzyme Active Site: Structural Studies of Three Highly Active Mutants of Escherichia coli Alkaline Phosphatase

Journal of molecular biology, 2002-03, Vol.316 (4), p.941-953

2002

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Genetic engineering of snake toxins. Role of invariant residues in the structural and functional properties of a curaremimetic toxin, as probed by site-directed mutagenesis

The Journal of biological chemistry, 1993-01, Vol.268 (2), p.909-916

1993

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Toxicity-based selection of Escherichia coli mutants for functional recombinant protein production: application to an antibody fragment

Protein engineering, design and selection, 2004-05, Vol.17 (5), p.491-500

2004

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Genetic engineering of snake toxins. The functional site of Erabutoxin a, as delineated by site-directed mutagenesis, includes variant residues

The Journal of biological chemistry, 1995-04, Vol.270 (16), p.9362-9369

1995

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Precursors of vertebrate peptide antibiotics dermaseptin b and adenoregulin have extensive sequence identities with precursors of opioid peptides dermorphin, dermenkephalin, and deltorphins

The Journal of biological chemistry, 1994-07, Vol.269 (27), p.17847-17852

1994

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Probing the topology of a bacterial membrane protein by genetic insertion of a foreign epitope; expression at the cell surface

The EMBO journal, 1986-11, Vol.5 (11), p.3029-3037

1986

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Recombinant antibody-alkaline phosphatase conjugates for diagnosis of human IgGs: application to anti-HBsAg detection

Journal of immunological methods, 1995-04, Vol.181 (2), p.177-186

1995

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Recombinant single-chain Fv antibody fragment–alkaline phosphatase conjugate for one-step immunodetection in molecular hybridization

Journal of immunological methods, 1999-07, Vol.227 (1), p.177-185

1999

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The low molecular weight protein which co-purifies with alpha-latrotoxin is structurally related to crustacean hyperglycemic hormones

The Journal of biological chemistry, 1994-08, Vol.269 (31), p.19803-19809

1994

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Cloning and sequence analysis of cDNAs encoding precursors of sarafotoxins. Evidence for an unusual "rosary-type" organization

The Journal of biological chemistry, 1993-02, Vol.268 (5), p.3052-3055

1993

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Mimicry between receptors and antibodies. Identification of snake toxin determinants recognized by the acetylcholine receptor and an acetylcholine receptor-mimicking monoclonal antibody

The Journal of biological chemistry, 1996-12, Vol.271 (49), p.31345-31353

1996

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Recombinant Colorimetric Antibodies: Construction and Characterization of a Bifunctional F(ab)2/Alkaline Phosphatase Conjugate Produced in Escherichia coli

Bio/technology (New York, N.Y. 1983), 1993-05, Vol.11 (5), p.601-605

1993

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Engineering of a recombinant colorimetric fusion protein for immunodiagnosis of insulin

Journal of immunological methods, 1996-10, Vol.197 (1), p.39-49

1996

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High-Level Production and Isotope Labeling of Snake Neurotoxins, Disulfide-Rich Proteins

Protein expression and purification, 1997-08, Vol.10 (3), p.293-300

1997

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Transformation of a non-enzymatic toxin into a toxoid by genetic engineering

Protein engineering, 1997-10, Vol.10 (10), p.1213-1220

1997

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A Recombinant Insect‐Specific α‐Toxin of Buthus occitanus tunetanus Scorpion Confers Protection Against Homologous Mammal Toxins

European Journal of Biochemistry, 1996-06, Vol.238 (3), p.653-660

1996

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Amino acid sequence of a muscarinic toxin deduced from the cDNA nucleotide sequence

Toxicon (Oxford), 1991, Vol.29 (4), p.516-520

1991

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A monoclonal antibody which recognized the functional site of snake neurotoxins and which neutralizes all short-chain variants

FEBS letters, 1986-11, Vol.208 (2), p.236-240

1986

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Do Structural Deviations between Toxins Adopting the Same Fold Reflect Functional Differences?

The Journal of biological chemistry, 2000-06, Vol.275 (24), p.18302-18310

2000

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A recombinant snake neurotoxin generated by chemical cleavage of a hybrid protein recovers full biological properties

FEBS letters, 1990-06, Vol.266 (1), p.87-90

1990

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Sequence analysis of a cDNA encoding a PLA2 from the sea-snake Aipysurus laevis

Nucleic acids research, 1988-09, Vol.16 (18), p.9048-9048

1988

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Regional and accelerated molecular evolution in group I snake venom gland phospholipase A2 isozymes

Toxicon (Oxford), 2000-03, Vol.38 (3), p.449-462

2000

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Complete amino acid sequence of a PLA2 from the tiger snake Notechis scutatus scutatus as deduced from a complementary DNA

Nucleic acids research, 1988-09, Vol.16 (18), p.9049-9049

1988

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Structure-Based Secondary Structure-Independent Approach To Design Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers

Improving Escherichia coli Alkaline Phosphatase Efficacy by Additional Mutations inside and outside the Catalytic Pocket

Artificial Evolution of an Enzyme Active Site: Structural Studies of Three Highly Active Mutants of Escherichia coli Alkaline Phosphatase

Genetic engineering of snake toxins. Role of invariant residues in the structural and functional properties of a curaremimetic toxin, as probed by site-directed mutagenesis

Toxicity-based selection of Escherichia coli mutants for functional recombinant protein production: application to an antibody fragment

Genetic engineering of snake toxins. The functional site of Erabutoxin a, as delineated by site-directed mutagenesis, includes variant residues

Precursors of vertebrate peptide antibiotics dermaseptin b and adenoregulin have extensive sequence identities with precursors of opioid peptides dermorphin, dermenkephalin, and deltorphins

Probing the topology of a bacterial membrane protein by genetic insertion of a foreign epitope; expression at the cell surface

Recombinant antibody-alkaline phosphatase conjugates for diagnosis of human IgGs: application to anti-HBsAg detection

Recombinant single-chain Fv antibody fragment–alkaline phosphatase conjugate for one-step immunodetection in molecular hybridization

The low molecular weight protein which co-purifies with alpha-latrotoxin is structurally related to crustacean hyperglycemic hormones

Cloning and sequence analysis of cDNAs encoding precursors of sarafotoxins. Evidence for an unusual "rosary-type" organization

Mimicry between receptors and antibodies. Identification of snake toxin determinants recognized by the acetylcholine receptor and an acetylcholine receptor-mimicking monoclonal antibody

Recombinant Colorimetric Antibodies: Construction and Characterization of a Bifunctional F(ab)2/Alkaline Phosphatase Conjugate Produced in Escherichia coli

Engineering of a recombinant colorimetric fusion protein for immunodiagnosis of insulin

High-Level Production and Isotope Labeling of Snake Neurotoxins, Disulfide-Rich Proteins

Transformation of a non-enzymatic toxin into a toxoid by genetic engineering

A Recombinant Insect‐Specific α‐Toxin of Buthus occitanus tunetanus Scorpion Confers Protection Against Homologous Mammal Toxins

Amino acid sequence of a muscarinic toxin deduced from the cDNA nucleotide sequence

A monoclonal antibody which recognized the functional site of snake neurotoxins and which neutralizes all short-chain variants

Do Structural Deviations between Toxins Adopting the Same Fold Reflect Functional Differences?

A recombinant snake neurotoxin generated by chemical cleavage of a hybrid protein recovers full biological properties

Sequence analysis of a cDNA encoding a PLA2 from the sea-snake Aipysurus laevis

Regional and accelerated molecular evolution in group I snake venom gland phospholipase A2 isozymes

Complete amino acid sequence of a PLA2 from the tiger snake Notechis scutatus scutatus as deduced from a complementary DNA

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