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Selective RET kinase inhibition for patients with RET-altered cancers
Annals of oncology, 2018-08, Vol.29 (8), p.1869-1876
2018
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Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1
Gene therapy, 2006-02, Vol.13 (3), p.225-234
2006
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391 LOXO-101, a pan TRK inhibitor, for the treatment of TRK-driven cancers
European journal of cancer (1990), 2014-11, Vol.50, p.125-125
2014
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The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers
European journal of cancer (1990), 2016-12, Vol.69, p.S144-S144
2016
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The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers
European journal of cancer (1990), 2016-12, Vol.69, p.S144-S145
2016
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Antitumor and Antimetastatic Activity of Ribozymes Targeting the Messenger RNA of Vascular Endothelial Growth Factor Receptors
Clinical cancer research, 2000-05, Vol.6 (5), p.2094-2103
2000
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Pharmacokinetics and Tissue Distribution of a Ribozyme Directed Against Hepatitis C Virus RNA Following Subcutaneous or Intravenous Administration in Mice
Hepatology (Baltimore, Md.), 2000-09, Vol.32 (3), p.640-646
2000
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Pre-clinical In Vitro and In Vivo Characterization of a Novel EGFR Sparing ErbB2 Inhibitor with Activity Against Oncogenic ErbB2 Mutations
European journal of cancer (1990), 2022-10, Vol.174, p.S81-S81
2022
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In Vivo Pre-clinical characterization of a Novel Series of FGFR2 Selective Inhibitors with Potency Against Clinically Relevant Mutations
European journal of cancer (1990), 2022-10, Vol.174, p.S81-S81
2022
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Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells
The Journal of biological chemistry, 1990-01, Vol.265 (1), p.445-451
1990
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162 MEK162 (ARRY-162), a novel MEK 1/2 inhibitor, inhibits tumor growth regardless of KRas/Raf pathway mutations
European journal of cancer supplements, 2010, Vol.8 (7), p.56-56
2010
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441 - The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers
European journal of cancer (1990), 2016-12, Vol.69, p.S144-S144
2016
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442 - The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers
European journal of cancer (1990), 2016-12, Vol.69, p.S144-S145
2016
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Sustained blockade of neurotrophin receptors TrkA, TrkB and TrkC reduces non-malignant skeletal pain but not the maintenance of sensory and sympathetic nerve fibers
Bone (New York, N.Y.), 2011-02, Vol.48 (2), p.389-398
2011
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Ribozymes as Tools for Therapeutic Target Validation in Arthritis
The Journal of immunology (1950), 2000-07, Vol.165 (1), p.493-498
2000
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In Vivo Activity of ARRY-380, a Potent, Small Molecule Inhibitor of ErbB2 in Combination with Trastuzumab, Docetaxel or Bevacizumab
Cancer research (Chicago, Ill.), 2009-12, Vol.69 (24_Supplement), p.5104-5104
2009
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Ribozyme pharmacokinetic screening for predicting pharmacodynamic dosing regimens
Current issues in molecular biology, 2000-10, Vol.2 (4), p.113
2000
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Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells
Cancer research (Chicago, Ill.), 1990-04, Vol.50 (8), p.2322-2329
1990
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Wound healing in the fetus. Possible role for inflammatory macrophages and transforming growth factor-beta isoforms
Wound repair and regeneration, 1994-03, Vol.2 (2), p.104-112
1994
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Pharmacokinetics of an antiangiogenic ribozyme (ANGIOZYME) in the mouse
Antisense & nucleic acid drug development, 1999-06, Vol.9 (3), p.271-277
1999
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Expression of metalloproteinases and metalloproteinases inhibitors by fetal astrocytes and glioma cells
Cancer research (Chicago, Ill.), 1990, Vol.50 (8), p.2322-2329
1990
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Abstract 1440: Identification of a novel EGFR sparing brain penetrant ErbB2 inhibitor with activity against oncogenic ErbB2 mutations
Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1440-1440
2023
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