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Mushroom-Derived Medicine? Preclinical Studies Suggest Potential Benefits of Ergothioneine for Cardiometabolic Health

International journal of molecular sciences, 2021-03, Vol.22 (6), p.3246

2021

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Non-parenchymal hepatic cell lipotoxicity and the coordinated progression of non-alcoholic fatty liver disease and atherosclerosis

Current opinion in lipidology, 2018-10, Vol.29 (5), p.417-422

2018

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Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

Journal of lipid research, 2006-12, Vol.47 (12), p.2726-2737

2006

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Differential Lipotoxic Effects of Palmitate and Oleate in Activated Human Hepatic Stellate Cells and Epithelial Hepatoma Cells

Cellular physiology and biochemistry, 2016-09, Vol.39 (4), p.1648-1662

2016

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Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis

PloS one, 2015-06, Vol.10 (6), p.e0131269-e0131269

2015

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The marine compound and elongation factor 1A1 inhibitor, didemnin B, provides benefit in western diet-induced non-alcoholic fatty liver disease

Pharmacological research, 2020-11, Vol.161, p.105208-105208, Article 105208

2020

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Two-Week Isocaloric Time-Restricted Feeding Decreases Liver Inflammation without Significant Weight Loss in Obese Mice with Non-Alcoholic Fatty Liver Disease

International journal of molecular sciences, 2020-12, Vol.21 (23), p.9156

2020

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Microarray data and pathway analyses for human microvascular endothelial cells supplemented with low dose vitamin D or niacin during lipotoxicity

Data in brief, 2019-10, Vol.26, p.104490-104490, Article 104490

2019

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Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes

Diabetes (New York, N.Y.), 2005-06, Vol.54 (6), p.1676-1683

2005

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A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death

Molecular biology of the cell, 2006-02, Vol.17 (2), p.770-778

2006

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Elongation factor 1A1 inhibition elicits changes in lipid droplet size, the bulk transcriptome, and cell type-associated gene expression in MASLD mouse liver

American journal of physiology: Gastrointestinal and liver physiology, 2024-10, Vol.327 (4), p.G608-G622

2024

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Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

Journal of lipid research, 2001-05, Vol.42 (5), p.725-734

2001

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Inhibition of Net HepG2 Cell Apolipoprotein B Secretion by the Citrus Flavonoid Naringenin Involves Activation of Phosphatidylinositol 3-Kinase, Independent of Insulin Receptor Substrate-1 Phosphorylation

Diabetes (New York, N.Y.), 2003-10, Vol.52 (10), p.2554-2561

2003

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NAD(+), sirtuins, and cardiovascular disease

Current pharmaceutical design, 2009, Vol.15 (1), p.110-117

2009

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Gene expression microarray data from human microvascular endothelial cells supplemented with a low concentration of niacin

Data in brief, 2016-03, Vol.6, p.899-902

2016

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Microarray data and pathway analyses for primary human activated hepatic stellate cells compared to HepG2 human hepatoma cells

Data in brief, 2017-02, Vol.10 (C), p.385-389

2017

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Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.105684-105684, Article 105684

2024

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Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

Biochemical journal, 2002-09, Vol.366 (Pt 2), p.531-539

2002

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Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin

Lipids, 1999-06, Vol.34 (6), p.591-598

1999

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Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment

Aging cell, 2009-04, Vol.8 (2), p.100-112

2009

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Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner

International Journal of Obesity, 2022-04, Vol.46 (4), p.726-738

2022

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Niacin receptor activation improves human microvascular endothelial cell angiogenic function during lipotoxicity

Atherosclerosis, 2014-12, Vol.237 (2), p.696-704

2014

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Vitamin D intervention does not improve vascular regeneration in diet-induced obese male mice with peripheral ischemia

The Journal of nutritional biochemistry, 2019-08, Vol.70, p.65-74

2019

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Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase

American Journal of Physiology: Cell Physiology, 2010-01, Vol.298 (1), p.C66-C74

2010

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Lipotoxicity in the heart

Current hypertension reports, 2005-12, Vol.7 (6), p.412-417

2005

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Mushroom-Derived Medicine? Preclinical Studies Suggest Potential Benefits of Ergothioneine for Cardiometabolic Health

Non-parenchymal hepatic cell lipotoxicity and the coordinated progression of non-alcoholic fatty liver disease and atherosclerosis

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

Differential Lipotoxic Effects of Palmitate and Oleate in Activated Human Hepatic Stellate Cells and Epithelial Hepatoma Cells

Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis

The marine compound and elongation factor 1A1 inhibitor, didemnin B, provides benefit in western diet-induced non-alcoholic fatty liver disease

Two-Week Isocaloric Time-Restricted Feeding Decreases Liver Inflammation without Significant Weight Loss in Obese Mice with Non-Alcoholic Fatty Liver Disease

Microarray data and pathway analyses for human microvascular endothelial cells supplemented with low dose vitamin D or niacin during lipotoxicity

Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes

A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death

Elongation factor 1A1 inhibition elicits changes in lipid droplet size, the bulk transcriptome, and cell type-associated gene expression in MASLD mouse liver

Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

Inhibition of Net HepG2 Cell Apolipoprotein B Secretion by the Citrus Flavonoid Naringenin Involves Activation of Phosphatidylinositol 3-Kinase, Independent of Insulin Receptor Substrate-1 Phosphorylation

NAD(+), sirtuins, and cardiovascular disease

Gene expression microarray data from human microvascular endothelial cells supplemented with a low concentration of niacin

Microarray data and pathway analyses for primary human activated hepatic stellate cells compared to HepG2 human hepatoma cells

Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells

Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin

Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment

Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner

Niacin receptor activation improves human microvascular endothelial cell angiogenic function during lipotoxicity

Vitamin D intervention does not improve vascular regeneration in diet-induced obese male mice with peripheral ischemia

Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase

Lipotoxicity in the heart

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