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Co-administration of Probenecid, an Inhibitor of a cMOAT/MRP- like Plasma Membrane ATPase, Greatly Enhanced the Efficacy of a New 10-Deazaaminopterin against Human Solid Tumors in Vivo

Clinical cancer research, 2000-09, Vol.6 (9), p.3705-3712

2000

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A case study exploring associations between popular media attention of scientific research and scientific citations

PloS one, 2020-07, Vol.15 (7), p.e0234912-e0234912

2020

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Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo

PloS one, 2010-11, Vol.5 (11), p.e14124

2010

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Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase

Cell, 2003-03, Vol.112 (6), p.859-871

2003

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Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

Cancer research (Chicago, Ill.), 2002-08, Vol.62 (15), p.4236-4243

2002

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Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation

PloS one, 2013-10, Vol.8 (10), p.e77262

2013

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Gleevec Inhibits β-Amyloid Production but Not Notch Cleavage

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.12444-12449

2003

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Curcumin glucuronides: Assessing the proliferative activity against human cell lines

Bioorganic & medicinal chemistry, 2014-01, Vol.22 (1), p.435-439

2014

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Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor

Molecular cancer therapeutics, 2009-05, Vol.8 (5), p.1157-1168

2009

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Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases

Cancer research (Chicago, Ill.), 2002-08, Vol.62 (15), p.4244-4255

2002

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PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

Blood, 2005-05, Vol.105 (10), p.3995-4003

2005

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Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics

The Journal of clinical investigation, 2004-10, Vol.114 (8), p.1107-1116

2004

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A cell-based screen for resistance of Bcr-Abl-positive leukemia identifies the mutation pattern for PD166326, an alternative Abl kinase inhibitor

Blood, 2005-02, Vol.105 (4), p.1652-1659

2005

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Inhibition of wild-type and mutant Bcr-Abl by pyrido-pyrimidine-type small molecule kinase inhibitors

Cancer research (Chicago, Ill.), 2003-10, Vol.63 (19), p.6395-6404

2003

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Total Synthesis of Baccatin III and Taxol

Journal of the American Chemical Society, 1996-03, Vol.118 (12), p.2843-2859

1996

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On the Interactivity of Complex Synthesis and Tumor Pharmacology in the Drug Discovery Process: Total Synthesis and Comparative in Vivo Evaluations of the 15-Aza Epothilones

Journal of organic chemistry, 2001-06, Vol.66 (12), p.4369-4378

2001

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Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

Nature genetics, 2004-08, Vol.36 (8), p.906-912

2004

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Susceptibility of cancer cells to β-lapachone is enhanced by ionizing radiation

International journal of radiation oncology, biology, physics, 2005, Vol.61 (1), p.212-219

2005

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Syntheses and biological evaluation of vinblastine congeners

Organic & biomolecular chemistry, 2003-06, Vol.1 (12), p.2120-2136

2003

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Synthesis and in vitro examination of [ 124I]-, [ 125I]- and [ 131I]-2-(4-iodophenylamino) pyrido[2,3- d]pyrimidin-7-one radiolabeled Abl kinase inhibitors

Nuclear medicine and biology, 2005-05, Vol.32 (4), p.313-321

2005

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Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene

Cancer gene therapy, 2004-12, Vol.11 (12), p.767-773

2004

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Inhibition of human immunodeficiency virus type 1 replication by 7-methyl-6,8-bis(methylthio)pyrrolo[1,2-a]pyrazine, an in vivo metabolite of oltipraz

Molecular pharmacology, 1995-07, Vol.48 (1), p.15-20

1995

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A simple synthesis of the multipurpose pheromone of Mus musculus

Journal of organic chemistry, 1984-12, Vol.49 (26), p.5264-5265

1984

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Formation and synthetic utility of dihydro- and dihydrothiapyrans

Journal of organic chemistry, 1979-02, Vol.44 (4), p.486-494

1979

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A novel entry into 3-acetylcyclohexanone via a cope rearrangement

Tetrahedron letters, 1978, Vol.19 (11), p.957-960

1978

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Co-administration of Probenecid, an Inhibitor of a cMOAT/MRP- like Plasma Membrane ATPase, Greatly Enhanced the Efficacy of a New 10-Deazaaminopterin against Human Solid Tumors in Vivo

A case study exploring associations between popular media attention of scientific research and scientific citations

Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo

Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase

Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation

Gleevec Inhibits β-Amyloid Production but Not Notch Cleavage

Curcumin glucuronides: Assessing the proliferative activity against human cell lines

Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor

Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases

PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics

A cell-based screen for resistance of Bcr-Abl-positive leukemia identifies the mutation pattern for PD166326, an alternative Abl kinase inhibitor

Inhibition of wild-type and mutant Bcr-Abl by pyrido-pyrimidine-type small molecule kinase inhibitors

Total Synthesis of Baccatin III and Taxol

On the Interactivity of Complex Synthesis and Tumor Pharmacology in the Drug Discovery Process: Total Synthesis and Comparative in Vivo Evaluations of the 15-Aza Epothilones

Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

Susceptibility of cancer cells to β-lapachone is enhanced by ionizing radiation

Syntheses and biological evaluation of vinblastine congeners

Synthesis and in vitro examination of [ 124I]-, [ 125I]- and [ 131I]-2-(4-iodophenylamino) pyrido[2,3- d]pyrimidin-7-one radiolabeled Abl kinase inhibitors

Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene

Inhibition of human immunodeficiency virus type 1 replication by 7-methyl-6,8-bis(methylthio)pyrrolo[1,2-a]pyrazine, an in vivo metabolite of oltipraz

A simple synthesis of the multipurpose pheromone of Mus musculus

Formation and synthetic utility of dihydro- and dihydrothiapyrans

A novel entry into 3-acetylcyclohexanone via a cope rearrangement

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