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Targeting of the E3 ubiquitin-protein ligase HUWE1 impairs DNA repair capacity and tumor growth in preclinical multiple myeloma models

Scientific reports, 2020-10, Vol.10 (1), p.18419, Article 18419

2020

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IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration

Journal of allergy and clinical immunology, 2016-05, Vol.137 (5), p.1487-1497.e6

2016

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A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease

PloS one, 2012-12, Vol.7 (12), p.e51892

2012

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Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma

Blood, 2005-11, Vol.106 (10), p.3609-3617

2005

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Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

Nature Immunology, 2006-02, Vol.7 (2), p.207-215

2006

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Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches

PloS one, 2014-10, Vol.9 (10), p.e109018-e109018

2014

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c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

The Journal of experimental medicine, 2004-04, Vol.199 (8), p.1041-1052

2004

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Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells

Blood, 2004-12, Vol.104 (12), p.3712-3721

2004

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Cleavage and Shedding of E-cadherin after Induction of Apoptosis

The Journal of biological chemistry, 2001-02, Vol.276 (7), p.4972-4980

2001

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Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells

The Journal of pathology, 2003-11, Vol.201 (3), p.413-420

2003

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Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation

Oncotarget, 2017-10, Vol.8 (49), p.85858-85867

2017

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In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway

Blood, 2002-11, Vol.100 (9), p.3311-3318

2002

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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Nature (London), 2024-02, Vol.626 (7998), p.401-410

2024

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Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

Nature (London), 1993-05, Vol.363 (6425), p.163-165

1993

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Signalling and survival pathways in multiple myeloma

European journal of cancer (1990), 2006-07, Vol.42 (11), p.1574-1580

2006

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Differential expression of Na+/K+‐ATPase α‐subunits in mouse hippocampal interneurones and pyramidal cells

The Journal of physiology, 2007-12, Vol.585 (2), p.491-505

2007

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Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-κB

The EMBO journal, 2002-08, Vol.21 (15), p.4104-4113

2002

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Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis

Blood, 2003-08, Vol.102 (3), p.1028-1034

2003

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Inhibition of CPP32 blocks surface IgM‐mediated apoptosis and D4‐GDI cleavage in human BL60 Burkitt lymphoma cells

European journal of immunology, 1998-01, Vol.28 (1), p.296-304

1998

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Elevated NF-κB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas

Blood, 2005-12, Vol.106 (13), p.4287-4293

2005

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STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90α and β in multiple myeloma cells, which critically contribute to tumor-cell survival

Blood, 2007-01, Vol.109 (2), p.720-728

2007

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Anti-CD20- and B-cell receptor-mediated apoptosis : Evidence for shared intracellular signaling pathways

Cancer research (Chicago, Ill.), 2000-12, Vol.60 (24), p.7170-7176

2000

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Preparative high-resolution two-dimensional electrophoresis enables the identification of RNA polymerase B transcription factor 3 as an apoptosis-associated protein in the human BL60-2 Burkitt lymphoma cell line

Journal of Protein Chemistry, 1999-02, Vol.18 (2), p.225-231

1999

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Novel CaV2.1 clone replicates many properties of Purkinje cell CaV2.1 current

The European journal of neuroscience, 2007-11, Vol.26 (10), p.2950-2961

2007

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Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells

Blood, 2006-03, Vol.107 (6), p.2536-2539

2006

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Leukemias. Malignant Lymphomas. Malignant Reticulosis. Myelofibrosis
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Targeting of the E3 ubiquitin-protein ligase HUWE1 impairs DNA repair capacity and tumor growth in preclinical multiple myeloma models

IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration

A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease

Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells

Cleavage and Shedding of E-cadherin after Induction of Apoptosis

Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells

Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation

In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

Signalling and survival pathways in multiple myeloma

Differential expression of Na+/K+‐ATPase α‐subunits in mouse hippocampal interneurones and pyramidal cells

Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-κB

Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis

Inhibition of CPP32 blocks surface IgM‐mediated apoptosis and D4‐GDI cleavage in human BL60 Burkitt lymphoma cells

Elevated NF-κB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas

STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90α and β in multiple myeloma cells, which critically contribute to tumor-cell survival

Anti-CD20- and B-cell receptor-mediated apoptosis : Evidence for shared intracellular signaling pathways

Preparative high-resolution two-dimensional electrophoresis enables the identification of RNA polymerase B transcription factor 3 as an apoptosis-associated protein in the human BL60-2 Burkitt lymphoma cell line

Novel CaV2.1 clone replicates many properties of Purkinje cell CaV2.1 current

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells

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