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The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry–Biology Interface

Journal of organic chemistry, 2017-12, Vol.82 (23), p.11961-11980

Boger, Dale L

2017

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Fe(III)/NaBH4‑Mediated Free Radical Hydrofluorination of Unactivated Alkenes

Journal of the American Chemical Society, 2012-08, Vol.134 (33), p.13588-13591

2012

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Total Syntheses of (−)-Kopsifoline D and (−)-Deoxoapodine: Divergent Total Synthesis via Late-Stage Key Strategic Bond Formation

Journal of the American Chemical Society, 2014-02, Vol.136 (8), p.3312-3317

2014

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Synthesis, Characterization, and Cycloaddition Reactivity of a Monocyclic Aromatic 1,2,3,5-Tetrazine

Journal of the American Chemical Society, 2019-10, Vol.141 (41), p.16388-16397

2019

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The quest for supernatural products: the impact of total synthesis in complex natural products medicinal chemistry

Natural product reports, 2020-11, Vol.37 (11), p.1511-1531

2020

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Inverse Electron Demand Diels–Alder Reactions of 1,2,3-Triazines: Pronounced Substituent Effects on Reactivity and Cycloaddition Scope

Journal of the American Chemical Society, 2011-08, Vol.133 (31), p.12285-12292

2011

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A Pd(0)-Mediated Indole (Macro)cyclization Reaction

Journal of the American Chemical Society, 2013-01, Vol.135 (4), p.1600-1606

2013

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Next-Generation Total Synthesis of Vancomycin

Journal of the American Chemical Society, 2020-09, Vol.142 (37), p.16039-16050

2020

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Total Synthesis and Stereochemical Assignment of Streptide

Journal of the American Chemical Society, 2019-10, Vol.141 (43), p.17361-17369

2019

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Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim

Journal of medicinal chemistry, 2019-03, Vol.62 (6), p.2938-2949

2019

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Fundamental Relationships between Structure, Reactivity, and Biological Activity for the Duocarmycins and CC-1065

Journal of medicinal chemistry, 2009-10, Vol.52 (19), p.5771-5780

2009

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Total synthesis of (−)-kopsinine and ent-(+)-kopsinine

Tetrahedron, 2015-06, Vol.71 (22), p.3741-3746

2015

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TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.E884-E893

2016

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Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine: Total Synthesis of (+)- and ent-(−)-Vinblastine

Journal of the American Chemical Society, 2008-01, Vol.130 (2), p.420-421

2008

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Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists

Journal of the American Chemical Society, 2018-10, Vol.140 (43), p.14440-14454

2018

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Scope of the Inverse Electron Demand Diels–Alder Reactions of 1,2,3-Triazine

Organic letters, 2011-05, Vol.13 (9), p.2492-2494

2011

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Inverse Electron Demand Diels–Alder Reactions of Heterocyclic Azadienes, 1‑Aza-1,3-Butadienes, Cyclopropenone Ketals, and Related Systems. A Retrospective

Journal of organic chemistry, 2019-08, Vol.84 (15), p.9397-9445

2019

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A Redesigned Vancomycin Engineered for Dual d-Ala-d-Ala and d-Ala-d-Lac Binding Exhibits Potent Antimicrobial Activity Against Vancomycin-Resistant Bacteria

Journal of the American Chemical Society, 2011-09, Vol.133 (35), p.13946-13949

2011

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Cycloadditions of Noncomplementary Substituted 1,2,3-Triazines

Organic letters, 2014-10, Vol.16 (19), p.5084-5087

2014

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Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites

Nature communications, 2021-11, Vol.12 (1), p.6942-11, Article 6942

2021

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Discovery of small-molecule enzyme activators by activity-based protein profiling

Nature chemical biology, 2020-09, Vol.16 (9), p.997

2020

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Total Synthesis of Lycogarubin C and Lycogalic Acid

Organic letters, 2010-03, Vol.12 (5), p.1132-1134

2010

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Mechanisms of in Situ Activation for DNA-Targeting Antitumor Agents

Chemical reviews, 2002-07, Vol.102 (7), p.2477-2496

2002

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Peripheral modifications of [Ψ[CH₂NH]Tpg⁴]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (26), p.E5052-E5061

2017

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Synthesis and Stereochemical Determination of Complestatin A and B (Neuroprotectin A and B)

Journal of the American Chemical Society, 2011-11, Vol.133 (45), p.18495-18502

2011

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The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry–Biology Interface

Fe(III)/NaBH4‑Mediated Free Radical Hydrofluorination of Unactivated Alkenes

Total Syntheses of (−)-Kopsifoline D and (−)-Deoxoapodine: Divergent Total Synthesis via Late-Stage Key Strategic Bond Formation

Synthesis, Characterization, and Cycloaddition Reactivity of a Monocyclic Aromatic 1,2,3,5-Tetrazine

The quest for supernatural products: the impact of total synthesis in complex natural products medicinal chemistry

Inverse Electron Demand Diels–Alder Reactions of 1,2,3-Triazines: Pronounced Substituent Effects on Reactivity and Cycloaddition Scope

A Pd(0)-Mediated Indole (Macro)cyclization Reaction

Next-Generation Total Synthesis of Vancomycin

Total Synthesis and Stereochemical Assignment of Streptide

Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim

Fundamental Relationships between Structure, Reactivity, and Biological Activity for the Duocarmycins and CC-1065

Total synthesis of (−)-kopsinine and ent-(+)-kopsinine

TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine: Total Synthesis of (+)- and ent-(−)-Vinblastine

Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists

Scope of the Inverse Electron Demand Diels–Alder Reactions of 1,2,3-Triazine

Inverse Electron Demand Diels–Alder Reactions of Heterocyclic Azadienes, 1‑Aza-1,3-Butadienes, Cyclopropenone Ketals, and Related Systems. A Retrospective

A Redesigned Vancomycin Engineered for Dual d-Ala-d-Ala and d-Ala-d-Lac Binding Exhibits Potent Antimicrobial Activity Against Vancomycin-Resistant Bacteria

Cycloadditions of Noncomplementary Substituted 1,2,3-Triazines

Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites

Discovery of small-molecule enzyme activators by activity-based protein profiling

Total Synthesis of Lycogarubin C and Lycogalic Acid

Mechanisms of in Situ Activation for DNA-Targeting Antitumor Agents

Peripheral modifications of [Ψ[CH₂NH]Tpg⁴]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics

Synthesis and Stereochemical Determination of Complestatin A and B (Neuroprotectin A and B)

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