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Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides

Journal of industrial microbiology & biotechnology, 2014-02, Vol.41 (2), p.443-450

Boddy, Christopher N.

2014

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Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?

Natural product reports, 2016-02, Vol.33 (2), p.183-202

2016

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ClusterMine360: a database of microbial PKS/NRPS biosynthesis

Nucleic acids research, 2013-01, Vol.41 (Database issue), p.D402-D407

2013

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Thioesterase from Cereulide Biosynthesis Is Responsible for Oligomerization and Macrocyclization of a Linear Tetradepsipeptide

Journal of natural products (Washington, D.C.), 2020-06, Vol.83 (6), p.1990-1997

2020

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Whole Genome Sequencing and Metabolomic Study of Cave Streptomyces Isolates ICC1 and ICC4

Frontiers in microbiology, 2019-05, Vol.10, p.1020-1020

2019

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Accessory Chromosome-Acquired Secondary Metabolism in Plant Pathogenic Fungi: The Evolution of Biotrophs Into Host-Specific Pathogens

Frontiers in microbiology, 2021-04, Vol.12, p.664276-664276

2021

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Characterization of Arthropeptide B, an Antifungal Cyclic Tetrapeptide from Arthrobacter humicola

Journal of chemical ecology, 2023-10, Vol.49 (9-10), p.528-536

2023

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Sampling Terrestrial Environments for Bacterial Polyketides

Molecules (Basel, Switzerland), 2017-04, Vol.22 (5), p.707

2017

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Biomineralization in Cave Bacteria—Popcorn and Soda Straw Crystal Formations, Morphologies, and Potential Metabolic Pathways

Frontiers in microbiology, 2022-07, Vol.13, p.933388-933388

2022

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Evolution of the Ergot Alkaloid Biosynthetic Gene Cluster Results in Divergent Mycotoxin Profiles in Claviceps purpurea Sclerotia

Toxins, 2021-12, Vol.13 (12), p.861

2021

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Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli

Nature chemical biology, 2006-08, Vol.2 (8), p.423-428

2006

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Gene PA2449 Is Essential for Glycine Metabolism and Pyocyanin Biosynthesis in Pseudomonas aeruginosa PAO1

Journal of Bacteriology, 2013-05, Vol.195 (9), p.2087-2100

2013

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The Use of ClusterMine360 for the Analysis of Polyketide and Nonribosomal Peptide Biosynthetic Pathways

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1401, p.233

2016

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Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis

Biochimica et biophysica acta, 2016-03, Vol.1860 (3), p.486-497

2016

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A Thioesterase from an Iterative Fungal Polyketide Synthase Shows Macrocyclization and Cross Coupling Activity and May Play a Role in Controlling Iterative Cycling through Product Offloading

Biochemistry (Easton), 2009-07, Vol.48 (27), p.6288-6290

2009

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CRISPR-Cas9 Gene Editing and Secondary Metabolite Screening Confirm Fusarium graminearum C16 Biosynthetic Gene Cluster Products as Decalin-Containing Diterpenoid Pyrones

Journal of fungi (Basel), 2023-06, Vol.9 (7), p.695

2023

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Portable, On-Demand Biomolecular Manufacturing

Cell, 2016-09, Vol.167 (1), p.248-259.e12

2016

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Double Stranded DNA Binding Stapled Peptides: An Emerging Tool for Transcriptional Regulation

Chembiochem : a European journal of chemical biology, 2023-12, Vol.24 (24), p.e202300594-n/a

2023

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Untargeted metabolomics screening reveals unique secondary metabolite production from Alternaria section Alternaria

Frontiers in molecular biosciences, 2022-11, Vol.9, p.1038299

2022

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Examining the Role of Hydrogen Bonding Interactions in the Substrate Specificity for the Loading Step of Polyketide Synthase Thioesterase Domains

Biochemistry (Easton), 2008-11, Vol.47 (45), p.11793-11803

2008

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Elucidation of Gephyronic Acid Biosynthetic Pathway Revealed Unexpected SAM-Dependent Methylations

Journal of natural products (Washington, D.C.), 2013-12, Vol.76 (12), p.2269-2276

2013

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Macrocyclization strategies for the total synthesis of cyclic depsipeptides

Organic & biomolecular chemistry, 2023-10, Vol.21 (4), p.843-853

2023

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Thioesterases as tools for chemoenzymatic synthesis of macrolactones

Chemical communications (Cambridge, England), 2024-03, Vol.6 (25), p.3379-3388

2024

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Atropselective Macrocyclization of Diaryl Ether Ring Systems: Application to the Synthesis of Vancomycin Model Systems

Journal of the American Chemical Society, 2002-09, Vol.124 (35), p.10451-10455

2002

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Heterologous Expression of the Oxytetracycline Biosynthetic Pathway in Myxococcus xanthus

Applied and Environmental Microbiology, 2010-04, Vol.76 (8), p.2681-2683

2010

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Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides

Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?

ClusterMine360: a database of microbial PKS/NRPS biosynthesis

Thioesterase from Cereulide Biosynthesis Is Responsible for Oligomerization and Macrocyclization of a Linear Tetradepsipeptide

Whole Genome Sequencing and Metabolomic Study of Cave Streptomyces Isolates ICC1 and ICC4

Accessory Chromosome-Acquired Secondary Metabolism in Plant Pathogenic Fungi: The Evolution of Biotrophs Into Host-Specific Pathogens

Characterization of Arthropeptide B, an Antifungal Cyclic Tetrapeptide from Arthrobacter humicola

Sampling Terrestrial Environments for Bacterial Polyketides

Biomineralization in Cave Bacteria—Popcorn and Soda Straw Crystal Formations, Morphologies, and Potential Metabolic Pathways

Evolution of the Ergot Alkaloid Biosynthetic Gene Cluster Results in Divergent Mycotoxin Profiles in Claviceps purpurea Sclerotia

Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli

Gene PA2449 Is Essential for Glycine Metabolism and Pyocyanin Biosynthesis in Pseudomonas aeruginosa PAO1

The Use of ClusterMine360 for the Analysis of Polyketide and Nonribosomal Peptide Biosynthetic Pathways

Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis

A Thioesterase from an Iterative Fungal Polyketide Synthase Shows Macrocyclization and Cross Coupling Activity and May Play a Role in Controlling Iterative Cycling through Product Offloading

CRISPR-Cas9 Gene Editing and Secondary Metabolite Screening Confirm Fusarium graminearum C16 Biosynthetic Gene Cluster Products as Decalin-Containing Diterpenoid Pyrones

Portable, On-Demand Biomolecular Manufacturing

Double Stranded DNA Binding Stapled Peptides: An Emerging Tool for Transcriptional Regulation

Untargeted metabolomics screening reveals unique secondary metabolite production from Alternaria section Alternaria

Examining the Role of Hydrogen Bonding Interactions in the Substrate Specificity for the Loading Step of Polyketide Synthase Thioesterase Domains

Elucidation of Gephyronic Acid Biosynthetic Pathway Revealed Unexpected SAM-Dependent Methylations

Macrocyclization strategies for the total synthesis of cyclic depsipeptides

Thioesterases as tools for chemoenzymatic synthesis of macrolactones

Atropselective Macrocyclization of Diaryl Ether Ring Systems: Application to the Synthesis of Vancomycin Model Systems

Heterologous Expression of the Oxytetracycline Biosynthetic Pathway in Myxococcus xanthus

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