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Distinct perturbation of the translatome by the antidiabetic drug metformin

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (23), p.8977-8982

2012

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A phenotype of IGFBP-3 knockout mice revealed by dextran sulfate-induced colitis

Journal of gastroenterology and hepatology, 2017-01, Vol.32 (1), p.146-153

2017

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Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth

Endocrine-related cancer, 2008-09, Vol.15 (3), p.833-839

2008

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Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

Molecular metabolism (Germany), 2022-07, Vol.61, p.101498-101498, Article 101498

2022

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Serine deprivation enhances antineoplastic activity of biguanides

Cancer research (Chicago, Ill.), 2014-12, Vol.74 (24), p.7521-7533

2014

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Metformin improves healthspan and lifespan in mice

Nature communications, 2013-07, Vol.4, p.2192-9

2013

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Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells

Breast cancer research and treatment, 2010-08, Vol.123 (1), p.271-279

2010

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Metformin improves healthspan and lifespan in mice

Nature communications, 2013-07, Vol.4 (1), Article 2192

2013

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Carbon Source and Myc Expression Influence the Antiproliferative Actions of Metformin

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (23), p.6257-6267

2012

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Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts

PloS one, 2013-11, Vol.8 (11), p.e79710

2013

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Germ line knockout of IGFBP-3 reveals influences of the gene on mammary gland neoplasia

Breast cancer research and treatment, 2015-02, Vol.149 (3), p.577-585

2015

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Dietary Feeding of Silibinin Inhibits Prostate Tumor Growth and Progression in Transgenic Adenocarcinoma of the Mouse Prostate Model

Cancer research (Chicago, Ill.), 2007-11, Vol.67 (22), p.11083-11091

2007

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Effects of castration on insulin levels and glucose tolerance in the mouse differ from those in man

The Prostate, 2010-11, Vol.70 (15), p.1628-1635

2010

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Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft

Carcinogenesis (New York), 2007-12, Vol.28 (12), p.2567-2574

2007

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Loss of function of PTEN alters the relationship between glucose concentration and cell proliferation, increases glycolysis, and sensitizes cells to 2-deoxyglucose

Cancer letters, 2010-03, Vol.289 (2), p.246-253

2010

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IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer

Endocrine-related cancer, 2011-12, Vol.18 (6), p.699-709

2011

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The hedgehog pathway inhibitor cyclopamine increases levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells

Cancer letters, 2007-10, Vol.255 (2), p.300-306

2007

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Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway

Endocrine-related cancer, 2012-08, Vol.19 (4), p.557-574

2012

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A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model

Oncogene, 2005-07, Vol.24 (29), p.4736-4740

2005

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Metformin abolishes increased tumor (18)F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet

Cell cycle (Georgetown, Tex.), 2011-08, Vol.10 (16), p.2770-2778

2011

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Genetic correction of sickle cell disease: Insights using transgenic mouse models

Nature medicine, 2000-02, Vol.6 (2), p.177-182

2000

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Insulin-like growth factor receptor I targeting in epithelial ovarian cancer

Gynecologic oncology, 2006-02, Vol.100 (2), p.389-396

2006

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Differential regulatory and compensatory responses in hematopoiesis/erythropoiesis in alpha- and beta-globin hemizygous mice

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.19471-19480

2004

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Metformin abolishes increased tumor 18F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet

Cell cycle (Georgetown, Tex.), 2011-08, Vol.10 (16), p.2770-2778

2011

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Distinct perturbation of the translatome by the antidiabetic drug metformin

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

A phenotype of IGFBP-3 knockout mice revealed by dextran sulfate-induced colitis

Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth

Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

Serine deprivation enhances antineoplastic activity of biguanides

Metformin improves healthspan and lifespan in mice

Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells

Metformin improves healthspan and lifespan in mice

Carbon Source and Myc Expression Influence the Antiproliferative Actions of Metformin

Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts

Germ line knockout of IGFBP-3 reveals influences of the gene on mammary gland neoplasia

Dietary Feeding of Silibinin Inhibits Prostate Tumor Growth and Progression in Transgenic Adenocarcinoma of the Mouse Prostate Model

Effects of castration on insulin levels and glucose tolerance in the mouse differ from those in man

Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft

Loss of function of PTEN alters the relationship between glucose concentration and cell proliferation, increases glycolysis, and sensitizes cells to 2-deoxyglucose

IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer

The hedgehog pathway inhibitor cyclopamine increases levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells

Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway

A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model

Metformin abolishes increased tumor (18)F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet

Genetic correction of sickle cell disease: Insights using transgenic mouse models

Insulin-like growth factor receptor I targeting in epithelial ovarian cancer

Differential regulatory and compensatory responses in hematopoiesis/erythropoiesis in alpha- and beta-globin hemizygous mice

Metformin abolishes increased tumor 18F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet

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