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Neuropharmacology of AMPA and kainate receptors

Neuropharmacology, 1998-10, Vol.37 (10), p.1187-1204

1998

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AMPA receptor potentiators for the treatment of CNS disorders

Current drug targets. CNS & neurological disorders, 2004-06, Vol.3 (3), p.181

2004

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A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus

Neuron (Cambridge, Mass.), 2003-07, Vol.39 (2), p.327-341

2003

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A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP

Neuron (Cambridge, Mass.), 2001-11, Vol.32 (4), p.697-709

2001

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A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission

Nature (London), 1997-10, Vol.389 (6651), p.599-603

1997

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Synthesis and Pharmacology of Willardiine Derivatives Acting as Antagonists of Kainate Receptors

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7867-7881

2005

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Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo

The Journal of pharmacology and experimental therapeutics, 2006-08, Vol.318 (2), p.772

2006

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Glutamate receptors and pain

Seminars in cell & developmental biology, 2006-10, Vol.17 (5), p.592-604

2006

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Antiallodynic and antihyperalgesic effects of selective competitive GLUK5 (GluR5) ionotropic glutamate receptor antagonists in the capsaicin and carrageenan models in rats

The Journal of pharmacology and experimental therapeutics, 2006-10, Vol.319 (1), p.396

2006

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A role for AMPA receptors in mood disorders

Biochemical pharmacology, 2006-04, Vol.71 (9), p.1273-1288

2006

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Mapping the functional effects of the AMPA receptor potentiators LY450108 and LY451395 with 14 C 2-deoxyglucose autoradiography

Journal of cerebral blood flow and metabolism, 2016-12, Vol.25 (1_suppl), p.S410-S410

2016

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AMPA receptors in the therapeutic management of depression

CNS & neurological disorders drug targets, 2007-04, Vol.6 (2), p.117

2007

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Human autoantibodies specific for the α1A calcium channel subunit reduce both P-type and Q-type calcium currents in cerebellar neurons

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (14), p.8328-8333

1998

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Test–retest reliability of evoked heat stimulation BOLD fMRI

Journal of neuroscience methods, 2015-09, Vol.253, p.38-46

2015

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Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro : Stereospecificity and selectivity profiles

Neuropharmacology, 1996-01, Vol.35 (12), p.1689-1702

1996

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Design and Synthesis of a Novel Series of 1,2-Disubstituted Cyclopentanes as Small, Potent Potentiators of 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic Acid (AMPA) Receptors

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.2101-2111

2002

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Imaging Drugs with and without Clinical Analgesic Efficacy

Neuropsychopharmacology (New York, N.Y.), 2011-12, Vol.36 (13), p.2659-2673

2011

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Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine

NeuroImage (Orlando, Fla.), 2012-02, Vol.59 (4), p.3762-3773

2012

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Mechanism of presynaptic inhibition by neuropeptide Y at sympathetic nerve terminals

Nature (London), 1993-08, Vol.364 (6438), p.635-639

1993

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Synthesis and Pharmacological Characterization of N3-Substituted Willardiine Derivatives: Role of the Substituent at the 5-Position of the Uracil Ring in the Development of Highly Potent and Selective GLUK5 Kainate Receptor Antagonists

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1558-1570

2007

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Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain

Drug discovery today, 2012-09, Vol.17 (17-18), p.964-973

2012

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Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects

The Journal of pharmacology and experimental therapeutics, 2013-04, Vol.345 (1), p.41

2013

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A ‘BOLD’ experiment in defining the utility of fMRI in drug development

NeuroImage (Orlando, Fla.), 2008-08, Vol.42 (2), p.461-466

2008

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Pharmacological Modulation of GluK1 and GluK2 by NETO1, NETO2, and PSD95

Assay and drug development technologies, 2016-03, Vol.14 (2), p.131

2016

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The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

Neuropharmacology of AMPA and kainate receptors

AMPA receptor potentiators for the treatment of CNS disorders

A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus

A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP

A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission

Synthesis and Pharmacology of Willardiine Derivatives Acting as Antagonists of Kainate Receptors

Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo

Glutamate receptors and pain

Antiallodynic and antihyperalgesic effects of selective competitive GLUK5 (GluR5) ionotropic glutamate receptor antagonists in the capsaicin and carrageenan models in rats

A role for AMPA receptors in mood disorders

Mapping the functional effects of the AMPA receptor potentiators LY450108 and LY451395 with 14 C 2-deoxyglucose autoradiography

AMPA receptors in the therapeutic management of depression

Human autoantibodies specific for the α1A calcium channel subunit reduce both P-type and Q-type calcium currents in cerebellar neurons

Test–retest reliability of evoked heat stimulation BOLD fMRI

Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro : Stereospecificity and selectivity profiles

Design and Synthesis of a Novel Series of 1,2-Disubstituted Cyclopentanes as Small, Potent Potentiators of 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic Acid (AMPA) Receptors

Imaging Drugs with and without Clinical Analgesic Efficacy

Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine

Mechanism of presynaptic inhibition by neuropeptide Y at sympathetic nerve terminals

Synthesis and Pharmacological Characterization of N3-Substituted Willardiine Derivatives: Role of the Substituent at the 5-Position of the Uracil Ring in the Development of Highly Potent and Selective GLUK5 Kainate Receptor Antagonists

Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain

Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects

A ‘BOLD’ experiment in defining the utility of fMRI in drug development

Pharmacological Modulation of GluK1 and GluK2 by NETO1, NETO2, and PSD95

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