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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (43), p.17450-17455

2013

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The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

Vaccine, 2012-03, Vol.30 (12), p.2060-2067

2012

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Granzyme B: a natural born killer

Immunological reviews, 2003-06, Vol.193 (1), p.31-38

2003

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Cloning CTL-Specific Genes (And Now for Something Completely Differential)

Frontiers in immunology, 2014-10, Vol.5, p.509-509

Bleackley, R Chris

2014

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Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3

PLoS pathogens, 2011-12, Vol.7 (12), p.e1002447

2011

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The Human Host Defense Peptide LL-37 Induces Apoptosis in a Calpain- and Apoptosis-Inducing Factor–Dependent Manner Involving Bax Activity

Molecular cancer research, 2009-05, Vol.7 (5), p.689-702

2009

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Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism

Journal of Virology, 2012-02, Vol.86 (4), p.2229-2238

2012

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Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

Nature immunology, 2011-08, Vol.12 (8), p.770

2011

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Granzyme B-Induced Apoptosis Requires Both Direct Caspase Activation and Relief of Caspase Inhibition

Immunity (Cambridge, Mass.), 2003-03, Vol.18 (3), p.355-365

2003

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Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis

The Journal of cell biology, 2000-08, Vol.150 (4), p.731-740

2000

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Cytotoxic T lymphocytes: all roads lead to death

Nature reviews. Immunology, 2002-06, Vol.2 (6), p.401-409

2002

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CD4+CD25+CD127dimFoxp3+ T cells are cytotoxic for human neurons

Journal of leukocyte biology, 2011-06, Vol.89 (6), p.927-934

2011

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Identification of a Novel Human Granzyme B Inhibitor Secreted by Cultured Sertoli Cells

Journal of Immunology, 2006-10, Vol.177 (8), p.5051-5058

2006

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Protection of porcine islet xenografts in mice using sertoli cells and monoclonal antibodies

Transplantation, 2011-12, Vol.92 (12), p.1309

2011

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Expression of CTL Associated Transcripts Precedes the Development of Tubulitis in T‐Cell Mediated Kidney Graft Rejection

American journal of transplantation, 2005-08, Vol.5 (8), p.1827-1836

2005

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Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo

Journal of neuroinflammation, 2015-09, Vol.12 (1), p.157-157, Article 157

2015

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T Cell Responses Are Better Correlates of Vaccine Protection in the Elderly

Journal of Immunology, 2006-05, Vol.176 (10), p.6333-6339

2006

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The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore

The Journal of experimental medicine, 2002-11, Vol.196 (9), p.1127-1139

2002

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Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

Journal of molecular medicine (Berlin, Germany), 2011-08, Vol.89 (8), p.771-783

2011

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Blockade of Granzyme B Remarkably Improves Mucocutaneous Diseases with Keratinocyte Death in Interface Dermatitis

Journal of investigative dermatology, 2018-09, Vol.138 (9), p.2079-2083

2018

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Comparison of single versus booster dose of influenza vaccination on humoral and cellular immune responses in older adults

Vaccine, 2005-05, Vol.23 (25), p.3294-3300

2005

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Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis

Blood, 1998-08, Vol.92 (3), p.1044-1054

1998

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Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults

Vaccine, 2009-04, Vol.27 (18), p.2418-2425

2009

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A novel mechanism of regulatory T cell-mediated down-regulation of autoimmunity

International immunology, 2006-07, Vol.18 (7), p.1001-1015

2006

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Granzyme B Induces Endothelial Cell Apoptosis and Contributes to the Development of Transplant Vascular Disease

American journal of transplantation, 2005-03, Vol.5 (3), p.494-499

2005

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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

Granzyme B: a natural born killer

Cloning CTL-Specific Genes (And Now for Something Completely Differential)

Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3

The Human Host Defense Peptide LL-37 Induces Apoptosis in a Calpain- and Apoptosis-Inducing Factor–Dependent Manner Involving Bax Activity

Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

Granzyme B-Induced Apoptosis Requires Both Direct Caspase Activation and Relief of Caspase Inhibition

Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis

Cytotoxic T lymphocytes: all roads lead to death

CD4+CD25+CD127dimFoxp3+ T cells are cytotoxic for human neurons

Identification of a Novel Human Granzyme B Inhibitor Secreted by Cultured Sertoli Cells

Protection of porcine islet xenografts in mice using sertoli cells and monoclonal antibodies

Expression of CTL Associated Transcripts Precedes the Development of Tubulitis in T‐Cell Mediated Kidney Graft Rejection

Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo

T Cell Responses Are Better Correlates of Vaccine Protection in the Elderly

The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

Blockade of Granzyme B Remarkably Improves Mucocutaneous Diseases with Keratinocyte Death in Interface Dermatitis

Comparison of single versus booster dose of influenza vaccination on humoral and cellular immune responses in older adults

Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis

Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults

A novel mechanism of regulatory T cell-mediated down-regulation of autoimmunity

Granzyme B Induces Endothelial Cell Apoptosis and Contributes to the Development of Transplant Vascular Disease

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