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Networking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments

Neuropsychopharmacology (New York, N.Y.), 2012-01, Vol.37 (1), p.196-212

2012

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Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities

Immunity (Cambridge, Mass.), 2019-02, Vol.50 (2), p.317-333.e6

2019

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The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction

Pflügers Archiv, 2014-01, Vol.466 (1), p.25-42

2014

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Interleukin-1 Receptor Activation by Systemic Lipopolysaccharide Induces Behavioral Despair Linked to MAPK Regulation of CNS Serotonin Transporters

Neuropsychopharmacology (New York, N.Y.), 2010-12, Vol.35 (13), p.2510-2520

2010

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The Proinflammatory Cytokines Interleukin-1beta and Tumor Necrosis Factor-Alpha Activate Serotonin Transporters

Neuropsychopharmacology (New York, N.Y.), 2006-10, Vol.31 (10), p.2121-2131

2006

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Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5469-5474

2012

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Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors

Nature communications, 2024-01, Vol.15 (1), p.417-417, Article 417

2024

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Rare Opportunities for Insights Into Serotonergic Contributions to Brain and Bowel Disorders: Studies of the SERT Ala56 Mouse

Frontiers in cellular neuroscience, 2021-06, Vol.15, p.677563-677563

2021

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Defective Presynaptic Choline Transport Underlies Hereditary Motor Neuropathy

American journal of human genetics, 2012-12, Vol.91 (6), p.1103-1107

2012

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Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

Nature communications, 2023-09, Vol.14 (1), p.6062-6062, Article 6062

2023

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Disruption of Transient Serotonin Accumulation by Non-Serotonin-Producing Neurons Impairs Cortical Map Development

Cell reports (Cambridge), 2015-01, Vol.10 (3), p.346-358

2015

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Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1

PloS one, 2016-03, Vol.11 (3), p.e0150068-e0150068

2016

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Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits

Cell reports (Cambridge), 2018-01, Vol.22 (1), p.255-268

2018

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rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (44), p.E4779-E4788

2014

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Dopamine-dependent, swimming-induced paralysis arises as a consequence of loss of function mutations in the RUNX transcription factor RNT-1

PloS one, 2019-05, Vol.14 (5), p.e0216417-e0216417

2019

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Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation

The Journal of neuroscience, 2012-04, Vol.32 (16), p.5385-5397

2012

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An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells

Neuropharmacology, 2016-11, Vol.110 (Pt A), p.438-448

2016

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Allelic Heterogeneity at the Serotonin Transporter Locus ( SLC6A4) Confers Susceptibility to Autism and Rigid-Compulsive Behaviors

American journal of human genetics, 2005-08, Vol.77 (2), p.265-279

2005

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Enhanced activity of human serotonin transporter variants associated with autism

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2009-01, Vol.364 (1514), p.163-173

2009

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Glial loss of the metallo β-lactamase domain containing protein, SWIP-10, induces age- and glutamate-signaling dependent, dopamine neuron degeneration

PLoS genetics, 2018-03, Vol.14 (3), p.e1007269-e1007269

2018

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The presynaptic choline transporter imposes limits on sustained cortical acetylcholine release and attention

The Journal of neuroscience, 2013-02, Vol.33 (6), p.2326-2337

2013

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The functional impact of SLC6 transporter genetic variation

Annual review of pharmacology and toxicology, 2007-01, Vol.47 (1), p.401-441

2007

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Sink or swim: Does a worm paralysis phenotype hold clues to neurodegenerative disease?

Journal of cellular physiology, 2024-06, Vol.239 (6), p.e31125-n/a

2024

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Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (37), p.14192-14197

2008

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Differential impact of genetically modulated choline transporter expression on the release of endogenous versus newly synthesized acetylcholine

Neurochemistry international, 2016-09, Vol.98, p.138-145

2016

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Networking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments

Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities

The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction

Interleukin-1 Receptor Activation by Systemic Lipopolysaccharide Induces Behavioral Despair Linked to MAPK Regulation of CNS Serotonin Transporters

The Proinflammatory Cytokines Interleukin-1beta and Tumor Necrosis Factor-Alpha Activate Serotonin Transporters

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors

Rare Opportunities for Insights Into Serotonergic Contributions to Brain and Bowel Disorders: Studies of the SERT Ala56 Mouse

Defective Presynaptic Choline Transport Underlies Hereditary Motor Neuropathy

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

Disruption of Transient Serotonin Accumulation by Non-Serotonin-Producing Neurons Impairs Cortical Map Development

Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1

Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits

rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants

Dopamine-dependent, swimming-induced paralysis arises as a consequence of loss of function mutations in the RUNX transcription factor RNT-1

Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation

An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells

Allelic Heterogeneity at the Serotonin Transporter Locus ( SLC6A4) Confers Susceptibility to Autism and Rigid-Compulsive Behaviors

Enhanced activity of human serotonin transporter variants associated with autism

Glial loss of the metallo β-lactamase domain containing protein, SWIP-10, induces age- and glutamate-signaling dependent, dopamine neuron degeneration

The presynaptic choline transporter imposes limits on sustained cortical acetylcholine release and attention

The functional impact of SLC6 transporter genetic variation

Sink or swim: Does a worm paralysis phenotype hold clues to neurodegenerative disease?

Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission

Differential impact of genetically modulated choline transporter expression on the release of endogenous versus newly synthesized acetylcholine

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