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Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production

Journal of medicinal chemistry, 2004-05, Vol.47 (11), p.2724-2727

2004

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The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2399-2403

2005

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Anticancer Activity and Cellular Repression of c-MYC by the G-Quadruplex-Stabilizing 11-Piperazinylquindoline Is Not Dependent on Direct Targeting of the G-Quadruplex in the c-MYC Promoter

Journal of medicinal chemistry, 2012-07, Vol.55 (13), p.6076-6086

2012

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Design and Synthesis of Piperazine-Based Matrix Metalloproteinase Inhibitors

Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.369-380

2000

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Design, Synthesis, and Biological Evaluation of Potent Thiazine- and Thiazepine-Based Matrix Metalloproteinase Inhibitors

Journal of medicinal chemistry, 1999-11, Vol.42 (22), p.4547-4562

1999

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Correction: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

Oncotarget, 2020-06, Vol.11 (26), p.2586-2586

2020

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Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

Oncotarget, 2020-05, Vol.11 (19), p.1758-1776

2020

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Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines

Journal of medicinal chemistry, 2001-03, Vol.44 (7), p.1060-1071

2001

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Design, Synthesis, and Biological Evaluation of Matrix Metalloproteinase Inhibitors Derived from a Modified Proline Scaffold

Journal of medicinal chemistry, 1999-12, Vol.42 (26), p.5426-5436

1999

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Erratum: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

Oncotarget, 2020-06, Vol.11 (26), p.2586-2586

2020

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The anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinyl quindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter

Journal of medicinal chemistry, 2012-06, Vol.55 (13), p.6076-6086

2012

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The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (15), p.1975-1979

2001

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The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

Bioorganic & medicinal chemistry letters, 2006-12, Vol.16 (23), p.5973-5977

2006

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Discovery of Potent, Achiral Matrix Metalloproteinase Inhibitors

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3568-3571

1998

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Oxazolidinone to succinamide: a novel rearrangement reaction

Tetrahedron letters, 1999-08, Vol.40 (33), p.5975-5977

1999

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Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1250-1253

2007

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The development of novel inhibitors of tumor necrosis factor-alpha production based on substituted [5,5]-bicyclic pyrozolones

Bioorganic & medicinal chemistry, 2010-11, Vol.14 ((16) ; 2004)

2010

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Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5633-5638

2006

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3-[4-(10H-Indolo[3,2-b]quinolin-11-yl)piperazin-1-yl]propan-1-ol

Acta crystallographica. Section E, Structure reports online, 2011-12, Vol.67 (Pt 12), p.o3465-o3466

2011

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The development of novel 1,2-dihydro-pyrimido[4,5- c]pyridazine based inhibitors of lymphocyte specific kinase (Lck)

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4257-4261

2006

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The development of new triazole based inhibitors of tumor necrosis factor-α (TNF-α) production

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1665-1668

2003

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Development of N-4,6-pyrimidine- N-alkyl- N′-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (14), p.3646-3650

2006

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Synthesis and evaluation of unsaturated caprolactams as interleukin-1β converting enzyme (ICE) inhibitors

Bioorganic & medicinal chemistry, 2007-02, Vol.15 (3), p.1311-1322

2007

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Development of N-2,4-pyrimidine-N-phenyl-N′-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 1

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3510-3513

2006

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The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-α production

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4360-4365

2006

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Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production

Anticancer Activity and Cellular Repression of c-MYC by the G-Quadruplex-Stabilizing 11-Piperazinylquindoline Is Not Dependent on Direct Targeting of the G-Quadruplex in the c-MYC Promoter

Design and Synthesis of Piperazine-Based Matrix Metalloproteinase Inhibitors

Design, Synthesis, and Biological Evaluation of Potent Thiazine- and Thiazepine-Based Matrix Metalloproteinase Inhibitors

Correction: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines

Design, Synthesis, and Biological Evaluation of Matrix Metalloproteinase Inhibitors Derived from a Modified Proline Scaffold

Erratum: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

The anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinyl quindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter

The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold

The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

Discovery of Potent, Achiral Matrix Metalloproteinase Inhibitors

Oxazolidinone to succinamide: a novel rearrangement reaction

Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)

The development of novel inhibitors of tumor necrosis factor-alpha production based on substituted [5,5]-bicyclic pyrozolones

Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3

3-[4-(10H-Indolo[3,2-b]quinolin-11-yl)piperazin-1-yl]propan-1-ol

The development of novel 1,2-dihydro-pyrimido[4,5- c]pyridazine based inhibitors of lymphocyte specific kinase (Lck)

The development of new triazole based inhibitors of tumor necrosis factor-α (TNF-α) production

Development of N-4,6-pyrimidine- N-alkyl- N′-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase

Synthesis and evaluation of unsaturated caprolactams as interleukin-1β converting enzyme (ICE) inhibitors

Development of N-2,4-pyrimidine-N-phenyl-N′-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 1

The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-α production

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