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Restoration of Vision with Ectopic Expression of Human Rod Opsin

Current biology, 2015-08, Vol.25 (16), p.2111-2122

2015

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Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration

Nature communications, 2020-02, Vol.11 (1), p.778-778, Article 778

2020

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Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration

The Journal of immunology (1950), 2014-11, Vol.193 (10), p.4962-4970

2014

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Iron, zinc, and copper in retinal physiology and disease

Survey of ophthalmology, 2013-11, Vol.58 (6), p.585-609

2013

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WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons

Science signaling, 2015-06, Vol.8 (383), p.ra65

2015

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Whole Genome Sequencing Increases Molecular Diagnostic Yield Compared with Current Diagnostic Testing for Inherited Retinal Disease

Ophthalmology (Rochester, Minn.), 2016-05, Vol.123 (5), p.1143-1150

2016

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Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

The Journal of biological chemistry, 2010-09, Vol.285 (39), p.30192-30202

2010

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Bruch's Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration

Frontiers in immunology, 2017-12, Vol.8, p.1778-1778

2017

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Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI

PloS one, 2020-08, Vol.15 (8), p.e0234672-e0234672

2020

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Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

PloS one, 2016-01, Vol.11 (1), p.e0147576

2016

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Viral Transduction of Human Rod Opsin or Channelrhodopsin Variants to Mouse ON Bipolar Cells Does Not Impact Retinal Anatomy or Cause Measurable Death in the Targeted Cells

International journal of molecular sciences, 2021-12, Vol.22 (23), p.13111

2021

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Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology

Biochemical Society transactions, 2010-10, Vol.38 (5), p.1342-1348

2010

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Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera

Investigative ophthalmology & visual science, 2012-11, Vol.53 (12), p.7528-7538

2012

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FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress

Scientific reports, 2021-07, Vol.11 (1), p.14175-17, Article 14175

2021

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Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans

Journal of structural biology, 2006-08, Vol.155 (2), p.294-305

2006

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Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera

Investigative ophthalmology & visual science, 2011-08, Vol.52 (9), p.6511-6521

2011

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Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes

Clinical epigenetics, 2019-01, Vol.11 (1), p.6-6, Article 6

2019

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Crystal Structure of the Dimeric Protein Core of Decorin, the Archetypal Small Leucine-Rich Repeat Proteoglycan

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (44), p.15633-15638

2004

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The role of extracellular matrix in retinal vascular development and preretinal neovascularization

Experimental eye research, 2015-04, Vol.133, p.30-36

Bishop, Paul N.

2015

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The eye as a complement dysregulation hotspot

Seminars in immunopathology, 2018-01, Vol.40 (1), p.65-74

2018

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The proteoglycan glycomatrix: a sugar microenvironment essential for complement regulation

Frontiers in immunology, 2013-11, Vol.4, p.412-412

2013

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A new strategy for MS/MS data acquisition applying multiple data dependent experiments on Orbitrap mass spectrometers in non-targeted metabolomic applications

Metabolomics, 2015-10, Vol.11 (5), p.1068-1080

2015

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Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice

Molecular therapy. Methods & clinical development, 2018-06, Vol.9, p.192-202

2018

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Age-related macular degeneration and the role of the complement system

Molecular immunology, 2015-09, Vol.67 (1), p.43-50

2015

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Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration

Journal of clinical medicine, 2014-12, Vol.4 (1), p.18-31

2014

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Restoration of Vision with Ectopic Expression of Human Rod Opsin

Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration

Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration

Iron, zinc, and copper in retinal physiology and disease

WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons

Whole Genome Sequencing Increases Molecular Diagnostic Yield Compared with Current Diagnostic Testing for Inherited Retinal Disease

Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

Bruch's Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration

Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

Viral Transduction of Human Rod Opsin or Channelrhodopsin Variants to Mouse ON Bipolar Cells Does Not Impact Retinal Anatomy or Cause Measurable Death in the Targeted Cells

Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology

Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera

FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress

Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans

Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera

Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes

Crystal Structure of the Dimeric Protein Core of Decorin, the Archetypal Small Leucine-Rich Repeat Proteoglycan

The role of extracellular matrix in retinal vascular development and preretinal neovascularization

The eye as a complement dysregulation hotspot

The proteoglycan glycomatrix: a sugar microenvironment essential for complement regulation

A new strategy for MS/MS data acquisition applying multiple data dependent experiments on Orbitrap mass spectrometers in non-targeted metabolomic applications

Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice

Age-related macular degeneration and the role of the complement system

Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration

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