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Triple Helix-Specific Ligands

Science (American Association for the Advancement of Science), 1992-06, Vol.256 (5064), p.1681-1684

1992

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Synthesis of psoralens and analogues

Journal of photochemistry and photobiology. B, Biology, 1992-06, Vol.14 (1), p.23-46

Bisagni, Emile

1992

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Synthesis and Antiviral Activity of 4-Benzyl Pyridinone Derivatives as Potent and Selective Non-Nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 2000-10, Vol.43 (21), p.3949-3962

2000

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Syntheses of 4-Benzylpyridones via Nucleophilic Aromatic Substitutions

Synthesis (Stuttgart), 2001, Vol.2001 (12), p.1806-1811

2001

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Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation

Bioorganic & medicinal chemistry, 2000-11, Vol.8 (11), p.2629

2000

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Spectroscopic study of the interaction of pazelliptine with nucleic acids

Journal of photochemistry and photobiology. B, Biology, 1997-10, Vol.40 (3), p.218-227

1997

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Rational Design of a Triple Helix-Specific Intercalating Ligand

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (7), p.3591-3596

1998

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4-Benzyl and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones: In Vitro Evaluation of New C-3-Amino-Substituted and C-5,6-Alkyl-Substituted Analogues against Clinically Important HIV Mutant Strains

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1948-1964

2005

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Binding geometries of triple helix selective benzopyrido [4,3-b]indole ligands complexed with double- and triple-helical polynucleotides

Biopolymers, 1997-07, Vol.42 (1), p.101-111

1997

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Genistein analogues: effects on epidermal growth factor receptor tyrosine kinase and on stress-activated pathways

Biomedicine & pharmacotherapy, 1997, Vol.51 (6), p.286-294

1997

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In vivo antitumor activity of S 16020-2, a new olivacine derivative

Cancer chemotherapy and pharmacology, 1996, Vol.38 (6), p.513-521

1996

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Photosensitized cross-linking and cleavage of pBR322 and M13 DNA: Comparison of 4,4′,6-trimethylangelicin and 3-carbethoxypsoralen

Journal of photochemistry and photobiology. B, Biology, 1994, Vol.22 (1), p.51-57

1994

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Triple-Helix Directed Cleavage of Double-Stranded DNA by Benzoquinoquinoxaline-1,10-phenanthroline Conjugates

Chembiochem : a European journal of chemical biology, 2004-11, Vol.5 (11), p.1550-1557

2004

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A New Access to 1-Naphthylamines by an Equivalent Semmler-Wolff Reaction

Synthesis (Stuttgart), 1993, Vol.1993 (1), p.57-59

1993

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Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors

Bioorganic & medicinal chemistry, 1999-07, Vol.7 (7), p.1281-1293

1999

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Synthesis of 9-O-Substituted Derivatives of 9-Hydroxy-5,6-dimethyl-6H- pyrido[4,3-b]carbazole-1-carboxylic Acid (2-(Dimethylamino)ethyl)amide and Their 10- and 11-Methyl Analogues with Improved Antitumor Activity

Journal of medicinal chemistry, 1999-06, Vol.42 (12), p.2191-2203

1999

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DNA-binding properties of a distamycin-ellipticine hybrid molecule

Molecular pharmacology, 1992-05, Vol.41 (5), p.845-855

1992

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5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation

Carcinogenesis (New York), 1981, Vol.2 (2), p.121-127

1981

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Synthesis of 13H-Benzo[6,7]- and 13H-Benzo[4,5]indolo[3,2-c]- quinolines: A New Series of Potent Specific Ligands for Triplex DNA

Journal of the American Chemical Society, 1998-03, Vol.120 (11), p.2501-2507

1998

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Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

Bioorganic & medicinal chemistry letters, 1998-04, Vol.8 (7), p.793-798

1998

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4-Benzyl- and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones, a New Family of Potent Anti-HIV Agents: Optimization and in Vitro Evaluation against Clinically Important HIV Mutant Strains

Journal of medicinal chemistry, 2004-10, Vol.47 (22), p.5501-5514

2004

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SPECTROSCOPIC PROPERTIES AND PHOTOREACTIVITY WITH DNA OF NEW MONOFUNCTIONAL PYRIDOPSORALENS

Photochemistry and photobiology, 1984-02, Vol.39 (2), p.145-156

1984

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A New Series of Pyridinone Derivatives as Potent Non-Nucleoside Human Immunodeficiency Virus Type 1 Specific Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 1995-11, Vol.38 (23), p.4679-4686

1995

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Synthesis and Evaluation of “AZT-HEPT”, “AZT-Pyridinone”, and “ddC-HEPT” Conjugates as Inhibitors of HIV Reverse Transcriptase

Journal of medicinal chemistry, 2000-05, Vol.43 (10), p.1927-1939

2000

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Stable Triple-Helical DNA Complexes Formed by Benzopyridoindole− and Benzopyridoquinoxaline− Oligonucleotide Conjugates

Journal of the American Chemical Society, 1997-01, Vol.119 (2), p.263-268

1997

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Triple Helix-Specific Ligands

Synthesis of psoralens and analogues

Synthesis and Antiviral Activity of 4-Benzyl Pyridinone Derivatives as Potent and Selective Non-Nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors

Syntheses of 4-Benzylpyridones via Nucleophilic Aromatic Substitutions

Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation

Spectroscopic study of the interaction of pazelliptine with nucleic acids

Rational Design of a Triple Helix-Specific Intercalating Ligand

4-Benzyl and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones: In Vitro Evaluation of New C-3-Amino-Substituted and C-5,6-Alkyl-Substituted Analogues against Clinically Important HIV Mutant Strains

Binding geometries of triple helix selective benzopyrido [4,3-b]indole ligands complexed with double- and triple-helical polynucleotides

Genistein analogues: effects on epidermal growth factor receptor tyrosine kinase and on stress-activated pathways

In vivo antitumor activity of S 16020-2, a new olivacine derivative

Photosensitized cross-linking and cleavage of pBR322 and M13 DNA: Comparison of 4,4′,6-trimethylangelicin and 3-carbethoxypsoralen

Triple-Helix Directed Cleavage of Double-Stranded DNA by Benzoquinoquinoxaline-1,10-phenanthroline Conjugates

A New Access to 1-Naphthylamines by an Equivalent Semmler-Wolff Reaction

Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors

Synthesis of 9-O-Substituted Derivatives of 9-Hydroxy-5,6-dimethyl-6H- pyrido[4,3-b]carbazole-1-carboxylic Acid (2-(Dimethylamino)ethyl)amide and Their 10- and 11-Methyl Analogues with Improved Antitumor Activity

DNA-binding properties of a distamycin-ellipticine hybrid molecule

5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation

Synthesis of 13H-Benzo[6,7]- and 13H-Benzo[4,5]indolo[3,2-c]- quinolines: A New Series of Potent Specific Ligands for Triplex DNA

Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

4-Benzyl- and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones, a New Family of Potent Anti-HIV Agents: Optimization and in Vitro Evaluation against Clinically Important HIV Mutant Strains

SPECTROSCOPIC PROPERTIES AND PHOTOREACTIVITY WITH DNA OF NEW MONOFUNCTIONAL PYRIDOPSORALENS

A New Series of Pyridinone Derivatives as Potent Non-Nucleoside Human Immunodeficiency Virus Type 1 Specific Reverse Transcriptase Inhibitors

Synthesis and Evaluation of “AZT-HEPT”, “AZT-Pyridinone”, and “ddC-HEPT” Conjugates as Inhibitors of HIV Reverse Transcriptase

Stable Triple-Helical DNA Complexes Formed by Benzopyridoindole− and Benzopyridoquinoxaline− Oligonucleotide Conjugates

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