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Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

British journal of clinical pharmacology, 1998-06, Vol.45 (6), p.525-538

1998

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Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2

The Journal of pharmacology and experimental therapeutics, 1993-04, Vol.265 (1), p.401

1993

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Nonspecific binding of drugs to human liver microsomes

British journal of clinical pharmacology, 2000-05, Vol.49 (5), p.453-461

2000

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Polymorphic hydroxylation of perhexiline in vitro

British journal of clinical pharmacology, 2003-06, Vol.55 (6), p.635-638

2003

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Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

Biochemical journal, 1993-01, Vol.289 (2), p.533-538

1993

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Identification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism

British journal of clinical pharmacology, 1994-06, Vol.37 (6), p.597-604

1994

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Diazepam metabolism by human liver microsomes is mediated by both S‐ mephenytoin hydroxylase and CYP3A isoforms

British journal of clinical pharmacology, 1994-08, Vol.38 (2), p.131-137

1994

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Caffeine metabolism by human hepatic cytochromes p450: Contributions of 1A2, 2E1 and 3A isoforms

Biochemical pharmacology, 1994-05, Vol.47 (10), p.1767-1776

1994

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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

British journal of clinical pharmacology, 1993-12, Vol.36 (6), p.521-530

1993

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Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine

British journal of clinical pharmacology, 1997-03, Vol.43 (3), p.245-252

1997

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Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism

The Journal of pharmacology and experimental therapeutics, 1995-03, Vol.272 (3), p.1076

1995

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Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9

Xenobiotica, 2004, Vol.34 (1), p.49-60

2004

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Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen

Biochemical pharmacology, 1996-04, Vol.51 (8), p.1003-1008

1996

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Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

Biochemical pharmacology, 1993-12, Vol.46 (11), p.1975-1981

1993

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In vitro approaches can predict human drug metabolism

Trends in pharmacological sciences (Regular ed.), 1993-08, Vol.14 (8), p.292-294

1993

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Pharmacodynamics of oxypurinol after administration of allopurinol to healthy subjects

British journal of clinical pharmacology, 1996-04, Vol.41 (4), p.299-304

1996

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Compliance with restrictions on the subsidized use of proton pump inhibitors in Australia

British journal of clinical pharmacology, 1998-10, Vol.46 (4), p.409-411

1998

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Changes to the Pharmaceutical Benefits Advisory Committee

Medical journal of Australia, 2001-03, Vol.174 (5), p.209-210

2001

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Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and p-xylene

The Journal of pharmacology and experimental therapeutics, 1996-01, Vol.276 (1), p.101

1996

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Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

British journal of clinical pharmacology, 1991-02, Vol.31 (2), p.125-130

1991

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Caffeine renal clearance and urine caffeine concentrations during steady state dosing. Implications for monitoring caffeine intake during sports events

British journal of clinical pharmacology, 1991-04, Vol.31 (4), p.405-408

1991

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Inhibition of human hepatic cytochrome P4502E1 by azole antifungals, CNS-active drugs and nonsteroidal anti-inflammatory agents

Xenobiotica, 1998, Vol.28 (3), p.293-301

1998

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Structural requirements for drug binding to site II on human serum albumin

Molecular pharmacology, 1983-11, Vol.24 (3), p.458-463

1983

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Tolbutamide hydroxylation by human liver microsomes: Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

Biochemical pharmacology, 1988-03, Vol.37 (6), p.1137-1144

1988

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A cost-effectiveness approach to drug subsidy and pricing in Australia

Health Affairs, 2001-05, Vol.20 (3), p.104-114

2001

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Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2

Nonspecific binding of drugs to human liver microsomes

Polymorphic hydroxylation of perhexiline in vitro

Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

Identification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism

Diazepam metabolism by human liver microsomes is mediated by both S‐ mephenytoin hydroxylase and CYP3A isoforms

Caffeine metabolism by human hepatic cytochromes p450: Contributions of 1A2, 2E1 and 3A isoforms

Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine

Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism

Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9

Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen

Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

In vitro approaches can predict human drug metabolism

Pharmacodynamics of oxypurinol after administration of allopurinol to healthy subjects

Compliance with restrictions on the subsidized use of proton pump inhibitors in Australia

Changes to the Pharmaceutical Benefits Advisory Committee

Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and p-xylene

Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

Caffeine renal clearance and urine caffeine concentrations during steady state dosing. Implications for monitoring caffeine intake during sports events

Inhibition of human hepatic cytochrome P4502E1 by azole antifungals, CNS-active drugs and nonsteroidal anti-inflammatory agents

Structural requirements for drug binding to site II on human serum albumin

Tolbutamide hydroxylation by human liver microsomes: Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

A cost-effectiveness approach to drug subsidy and pricing in Australia

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