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Mechanisms of clastogen-induced chromosomal aberrations: A critical review and description of a model based on failures of tethering of DNA strand ends to strand-breaking enzymes

Mutation research, 2009-03, Vol.681 (2-3), p.271-298

Bignold, L.P.

2009

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Variation, “evolution”, immortality and genetic instabilities in tumour cells

Cancer letters, 2007-08, Vol.253 (2), p.155-169

Bignold, L.P

2007

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Initiation of genetic instability and tumour formation: a review and hypothesis of a nongenotoxic mechanism

Cellular and molecular life sciences : CMLS, 2003-06, Vol.60 (6), p.1107-1117

Bignold, L P

2003

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The mutator phenotype theory of carcinogenesis and the complex histopathology of tumours: support for the theory from the independent occurrence of nuclear abnormality, loss of specialisation and invasiveness among occasional neoplastic lesions

Cellular and molecular life sciences : CMLS, 2003-05, Vol.60 (5), p.883-891

Bignold, L P

2003

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The mutator phenotype theory can explain the complex morphology and behaviour of cancers

Cellular and molecular life sciences : CMLS, 2002-06, Vol.59 (6), p.950-958

Bignold, L P

2002

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Carcinogen-induced impairment of enzymes for replicative fidelity of DNA and the initiation of tumours

Carcinogenesis (New York), 2004-03, Vol.25 (3), p.299-307

Bignold, Leon P

2004

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Inhibition of C5a-induced neutrophil chemotaxis and macrophage cytokine production in vitro by a new C5a receptor antagonist

Biochemical pharmacology, 2000-09, Vol.60 (5), p.729-733

2000

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Interleukin-5 transgenic mice show enhanced resistance to primary infections with Nippostrongylus brasiliensis but not primary infections with Toxocara canis

Infection and immunity, 1999-02, Vol.67 (2), p.989-993

1999

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Mutation, replicative infidelity of DNA and aneuploidy sequentially in the formation of malignant pleomorphic tumors

Histology and histopathology, 2007-03, Vol.22 (3), p.321

Bignold, L P

2007

Volltextzugriff (PDF)

Hypothesis for the influence of fixatives on the chromatin patterns of interphase nuclei, based on shrinkage and retraction of nuclear and perinuclear structures

British journal of biomedical science, 2002-01, Vol.59 (2), p.114-122

Bignold, L. P.

2002

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Gastrointestinal: Positron emission tomography scans and colonic polyps

Journal of gastroenterology and hepatology, 2004-12, Vol.19 (12), p.1420-1420

2004

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The cell-type-specificity of inherited predispositions to tumours: review and hypothesis

Cancer letters, 2004-12, Vol.216 (2), p.127-146

Bignold, Leon P.

2004

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Chaotic Genomes Make Chaotic Cells: The Mutator Phenotype Theory of Carcinogenesis Applied to Clinicopathological Relationships of Solid Tumors

Cancer investigation, 2004, Vol.22 (3), p.338-343

Bignold, L. P.

2004

Volltextzugriff (PDF)

Pathogenetic mechanisms of nuclear pleomorphism of tumour cells based on the mutator phenotype theory of carcinogenesis

Histology and histopathology, 2003-04, Vol.18 (2), p.657

Bignold, L P

2003

Volltextzugriff (PDF)

Inhibition of chemotaxis of neutrophil leukocytes to interleukin-8 by endotoxins of various bacteria

Infection and Immunity, 1991-11, Vol.59 (11), p.4255-4258

1991

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Mechanism of separation of polymorphonuclear leukocytes from whole blood by the one-step Hypaque-Ficoll method

Journal of immunological methods, 1987-01, Vol.96 (1), p.29-33

1987

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Measurement of chemotaxis of polymorphonuclear leukocytes in vitro: The problems of the control of gradients of chemotactic factors, of the control of the cells and of the separation of chemotaxis from chemokinesis

Journal of Immunological Methods, 1988-04, Vol.108 (1), p.1-18

Bignold, L.P.

1988

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Intraarticular rupture of digital tenosynovial calcification: an unusual case of acute arthritis of the finger

Journal of rheumatology, 1999-07, Vol.26 (7), p.1643

1999

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A novel polycarbonate (Nuclepore) membrane demonstrates chemotaxis, unaffected by chemokinesis, of polymorphonuclear leukocytes in the Boyden chamber

Journal of immunological methods, 1987-12, Vol.105 (2), p.275-280

Bignold, L.P.

1987

Volltextzugriff (PDF)

DNA-PROTEIN CLAMP DYSFUNCTION AS A MECHANISM OF CHROMOSOMAL ABBERATIONS INDUCED BY X-RAYS AND ALKYLATING AGENTS IN CANCER

Anticancer research, 2008-10, Vol.28 (5C)

Bignold, L P

2008

Volltextzugriff (PDF)

Use of sparse-pore polycarbonate (Nuclepore) membrane for the measurement of chemotaxis of polymorphonuclear leukocytes comparison of ‘micro-Boyden’ chambers and estimation of ‘drop-off’ of cells

Journal of immunological methods, 1989-03, Vol.118 (2), p.217-225

Bignold, L.P.

1989

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The eosinophil leukocyte: controversies of recruitment and function

Experientia, 1995-04, Vol.51 (4), p.317-327

Bignold, L P

1995

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Effects of plasma proteins on the adhesion, spreading, polarization in suspension, random motility and chemotaxis of neutrophil leukocytes on polycarbonate (nuclepore) filtration membrane

European journal of cell biology, 1990-10, Vol.53 (1), p.27-34

1990

Volltextzugriff (PDF)

Neutrophil polarisation in plasma differs to that induced by endogenous chemoattractants with regard to frequency of uropod formation and requirement for divalent cations

Cell biology international, 1994-03, Vol.18 (3), p.177-187

1994

Volltextzugriff (PDF)

DAVID PAUL HANSEMANN, CHROMOSOMES AND CANCER

Anticancer research, 2008-10, Vol.28 (5C)

2008

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Mechanisms of clastogen-induced chromosomal aberrations: A critical review and description of a model based on failures of tethering of DNA strand ends to strand-breaking enzymes

Variation, “evolution”, immortality and genetic instabilities in tumour cells

Initiation of genetic instability and tumour formation: a review and hypothesis of a nongenotoxic mechanism

The mutator phenotype theory of carcinogenesis and the complex histopathology of tumours: support for the theory from the independent occurrence of nuclear abnormality, loss of specialisation and invasiveness among occasional neoplastic lesions

The mutator phenotype theory can explain the complex morphology and behaviour of cancers

Carcinogen-induced impairment of enzymes for replicative fidelity of DNA and the initiation of tumours

Inhibition of C5a-induced neutrophil chemotaxis and macrophage cytokine production in vitro by a new C5a receptor antagonist

Interleukin-5 transgenic mice show enhanced resistance to primary infections with Nippostrongylus brasiliensis but not primary infections with Toxocara canis

Mutation, replicative infidelity of DNA and aneuploidy sequentially in the formation of malignant pleomorphic tumors

Hypothesis for the influence of fixatives on the chromatin patterns of interphase nuclei, based on shrinkage and retraction of nuclear and perinuclear structures

Gastrointestinal: Positron emission tomography scans and colonic polyps

The cell-type-specificity of inherited predispositions to tumours: review and hypothesis

Chaotic Genomes Make Chaotic Cells: The Mutator Phenotype Theory of Carcinogenesis Applied to Clinicopathological Relationships of Solid Tumors

Pathogenetic mechanisms of nuclear pleomorphism of tumour cells based on the mutator phenotype theory of carcinogenesis

Inhibition of chemotaxis of neutrophil leukocytes to interleukin-8 by endotoxins of various bacteria

Mechanism of separation of polymorphonuclear leukocytes from whole blood by the one-step Hypaque-Ficoll method

Measurement of chemotaxis of polymorphonuclear leukocytes in vitro: The problems of the control of gradients of chemotactic factors, of the control of the cells and of the separation of chemotaxis from chemokinesis

Intraarticular rupture of digital tenosynovial calcification: an unusual case of acute arthritis of the finger

A novel polycarbonate (Nuclepore) membrane demonstrates chemotaxis, unaffected by chemokinesis, of polymorphonuclear leukocytes in the Boyden chamber

DNA-PROTEIN CLAMP DYSFUNCTION AS A MECHANISM OF CHROMOSOMAL ABBERATIONS INDUCED BY X-RAYS AND ALKYLATING AGENTS IN CANCER

Use of sparse-pore polycarbonate (Nuclepore) membrane for the measurement of chemotaxis of polymorphonuclear leukocytes comparison of ‘micro-Boyden’ chambers and estimation of ‘drop-off’ of cells

The eosinophil leukocyte: controversies of recruitment and function

Effects of plasma proteins on the adhesion, spreading, polarization in suspension, random motility and chemotaxis of neutrophil leukocytes on polycarbonate (nuclepore) filtration membrane

Neutrophil polarisation in plasma differs to that induced by endogenous chemoattractants with regard to frequency of uropod formation and requirement for divalent cations

DAVID PAUL HANSEMANN, CHROMOSOMES AND CANCER

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