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In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens

Journal of antibiotics, 2021-12, Vol.74 (12), p.884-892

2021

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In Vitro Profiling of Ceftaroline against a Collection of Recent Bacterial Clinical Isolates from across the United States

Antimicrobial Agents and Chemotherapy, 2008-09, Vol.52 (9), p.3398-3407

2008

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CANVAS 1 and 2: Analysis of Clinical Response at Day 3 in Two Phase 3 Trials of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in Treatment of Acute Bacterial Skin and Skin Structure Infections

Antimicrobial Agents and Chemotherapy, 2012-05, Vol.56 (5), p.2231-2236

2012

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Serotype distribution and antimicrobial susceptibility of USA Streptococcus pneumoniae isolates collected prior to and post introduction of 13-valent pneumococcal conjugate vaccine

Diagnostic microbiology and infectious disease, 2014-09, Vol.80 (1), p.19-25

2014

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Efficacy of Ceftaroline Fosamil in a Staphylococcal Murine Pneumonia Model

Antimicrobial Agents and Chemotherapy, 2012-12, Vol.56 (12), p.6160-6165

2012

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Activity of Ceftaroline and Epidemiologic Trends in Staphylococcus aureus Isolates Collected from 43 Medical Centers in the United States in 2009

Antimicrobial Agents and Chemotherapy, 2011-09, Vol.55 (9), p.4154-4160

2011

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Activity of Ceftaroline against Recent Emerging Serotypes of Streptococcus pneumoniae in the United States

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2716-2719

2010

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Role in Cell Permeability of an Essential Two-Component System in Staphylococcus aureus

Journal of Bacteriology, 1999-06, Vol.181 (12), p.3666-3673

1999

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Ceftaroline versus Ceftriaxone in a Highly Penicillin-Resistant Pneumococcal Pneumonia Rabbit Model Using Simulated Human Dosing

Antimicrobial Agents and Chemotherapy, 2011-07, Vol.55 (7), p.3557-3563

2011

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In Vitro Evaluation of the Antimicrobial Activity of Ceftaroline against Cephalosporin-Resistant Isolates of Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy, 2009-02, Vol.53 (2), p.552-556

2009

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Evaluation of Ceftaroline Activity versus Ceftriaxone against Clinical Isolates of Streptococcus pneumoniae with Various Susceptibilities to Cephalosporins in an In Vitro Pharmacokinetic/Pharmacodynamic Model

Antimicrobial Agents and Chemotherapy, 2012-05, Vol.56 (5), p.2691-2695

2012

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Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies

PloS one, 2012-05, Vol.7 (5), p.e37212

2012

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Probing plasmid partition with centromere‐based incompatibility

Molecular microbiology, 2005-01, Vol.55 (2), p.511-525

2005

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In Vivo Activity of a Novel Anti-Methicillin-Resistant Staphylococcus aureus Cephalosporin, Ceftaroline, against Vancomycin-Susceptible and -Resistant Enterococcus faecalis Strains in a Rabbit Endocarditis Model: a Comparative Study with Linezolid and Vancomycin

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5300-5302

2009

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Ceftaroline: a Cephalosporin with Anti-MRSA Activity

Clinical microbiology newsletter, 2011-11, Vol.33 (21), p.161-169

2011

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Ceftaroline fosamil: a novel broad-spectrum cephalosporin with expanded anti-Gram-positive activity

Journal of antimicrobial chemotherapy, 2010-11, Vol.65 (suppl-4), p.iv9-iv16

2010

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Characterization of methicillin-resistant Staphylococcus aureus displaying increased MICs of ceftaroline

Journal of antimicrobial chemotherapy, 2012-06, Vol.67 (6), p.1321-1324

2012

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Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus

Journal of Bacteriology, 2001-05, Vol.183 (10), p.3016-3024

2001

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Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis

Journal of antimicrobial chemotherapy, 2010-08, Vol.65 (8), p.1749-1752

2010

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Review of ceftaroline fosamil microbiology: integrated FOCUS studies

Journal of antimicrobial chemotherapy, 2011-04, Vol.66 Suppl 3 (Supplement 3), p.iii45-iii51

2011

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Decreased Ceftriaxone Susceptibility in Emerging (35B and 6C) and Persisting (19A) Streptococcus pneumoniae Serotypes in the United States, 2011-2012: Ceftaroline Remains Active In Vitro among β-Lactam Agents

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4923-4927

2014

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A Single 43-bp sopC Repeat of Plasmid Mini-F is Sufficient to Allow Assembly of a Functional Nucleoprotein Partition Complex

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (17), p.8027-8031

1994

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Fosfomycin and Comparator Activity Against Select Enterobacteriaceae, Pseudomonas, and Enterococcus Urinary Tract Infection Isolates from the United States in 2012

Infectious diseases and therapy, 2017-06, Vol.6 (2), p.233-243

2017

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Evolution of Ceftaroline-Resistant Mrsa in a Child with Cystic Fibrosis Following Repeated Antibiotic Exposure

The Pediatric infectious disease journal, 2016-07, Vol.35 (7), p.813-815

2016

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In Vivo Efficacy of Ceftaroline Fosamil in a Methicillin-Resistant Panton-Valentine Leukocidin-Producing Staphylococcus aureus Rabbit Pneumonia Model

Antimicrobial agents and chemotherapy, 2014-04, Vol.58 (4), p.1855-1861

2014

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In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens

In Vitro Profiling of Ceftaroline against a Collection of Recent Bacterial Clinical Isolates from across the United States

CANVAS 1 and 2: Analysis of Clinical Response at Day 3 in Two Phase 3 Trials of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in Treatment of Acute Bacterial Skin and Skin Structure Infections

Serotype distribution and antimicrobial susceptibility of USA Streptococcus pneumoniae isolates collected prior to and post introduction of 13-valent pneumococcal conjugate vaccine

Efficacy of Ceftaroline Fosamil in a Staphylococcal Murine Pneumonia Model

Activity of Ceftaroline and Epidemiologic Trends in Staphylococcus aureus Isolates Collected from 43 Medical Centers in the United States in 2009

Activity of Ceftaroline against Recent Emerging Serotypes of Streptococcus pneumoniae in the United States

Role in Cell Permeability of an Essential Two-Component System in Staphylococcus aureus

Ceftaroline versus Ceftriaxone in a Highly Penicillin-Resistant Pneumococcal Pneumonia Rabbit Model Using Simulated Human Dosing

In Vitro Evaluation of the Antimicrobial Activity of Ceftaroline against Cephalosporin-Resistant Isolates of Streptococcus pneumoniae

Evaluation of Ceftaroline Activity versus Ceftriaxone against Clinical Isolates of Streptococcus pneumoniae with Various Susceptibilities to Cephalosporins in an In Vitro Pharmacokinetic/Pharmacodynamic Model

Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies

Probing plasmid partition with centromere‐based incompatibility

In Vivo Activity of a Novel Anti-Methicillin-Resistant Staphylococcus aureus Cephalosporin, Ceftaroline, against Vancomycin-Susceptible and -Resistant Enterococcus faecalis Strains in a Rabbit Endocarditis Model: a Comparative Study with Linezolid and Vancomycin

Ceftaroline: a Cephalosporin with Anti-MRSA Activity

Ceftaroline fosamil: a novel broad-spectrum cephalosporin with expanded anti-Gram-positive activity

Characterization of methicillin-resistant Staphylococcus aureus displaying increased MICs of ceftaroline

Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus

Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis

Review of ceftaroline fosamil microbiology: integrated FOCUS studies

Decreased Ceftriaxone Susceptibility in Emerging (35B and 6C) and Persisting (19A) Streptococcus pneumoniae Serotypes in the United States, 2011-2012: Ceftaroline Remains Active In Vitro among β-Lactam Agents

A Single 43-bp sopC Repeat of Plasmid Mini-F is Sufficient to Allow Assembly of a Functional Nucleoprotein Partition Complex

Fosfomycin and Comparator Activity Against Select Enterobacteriaceae, Pseudomonas, and Enterococcus Urinary Tract Infection Isolates from the United States in 2012

Evolution of Ceftaroline-Resistant Mrsa in a Child with Cystic Fibrosis Following Repeated Antibiotic Exposure

In Vivo Efficacy of Ceftaroline Fosamil in a Methicillin-Resistant Panton-Valentine Leukocidin-Producing Staphylococcus aureus Rabbit Pneumonia Model

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