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Microtubule-targeted anticancer agents and apoptosis

Oncogene, 2003-12, Vol.22 (56), p.9075-9086

Bhalla, Kapil N

2003

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Epigenetic and Chromatin Modifiers As Targeted Therapy of Hematologic Malignancies

Journal of clinical oncology, 2005-06, Vol.23 (17), p.3971-3993

BHALLA, Kapil N

2005

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Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

Cancer research (Chicago, Ill.), 2014-05, Vol.74 (9), p.2520-2532

2014

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Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6841-6846

2013

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Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia

Nature communications, 2021-05, Vol.12 (1), p.2607-2607, Article 2607

2021

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Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells

Molecular cancer therapeutics, 2014-05, Vol.13 (5), p.1142-1154

2014

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Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib

Blood, 2015-09, Vol.126 (13), p.1565-1574

2015

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Dual PI3K/AKT/mTOR inhibitor BEZ235 synergistically enhances the activity of JAK2 inhibitor against cultured and primary human myeloproliferative neoplasm cells

Molecular cancer therapeutics, 2013-05, Vol.12 (5), p.577-588

2013

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Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish

PloS one, 2012-01, Vol.7 (1), p.e29916-e29916

2012

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Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)

Blood cancer journal (New York), 2022-01, Vol.12 (1), p.5-5, Article 5

2022

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Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells

Molecular cancer therapeutics, 2012-04, Vol.11 (4), p.973-983

2012

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EVI1 dysregulation: impact on biology and therapy of myeloid malignancies

Blood cancer journal (New York), 2021-03, Vol.11 (3), p.64-64, Article 64

2021

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A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas

Nature medicine, 2009-12, Vol.15 (12), p.1369-1376

2009

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p53 Acetylation Is Crucial for Its Transcription-independent Proapoptotic Functions

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11171-11183

2009

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Anoikis, Initiated by Mcl-1 Degradation and Bim Induction, Is Deregulated during Oncogenesis

Cancer research (Chicago, Ill.), 2007-11, Vol.67 (22), p.10744-10752

2007

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Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1

Blood cancer journal (New York), 2023-04, Vol.13 (1), p.53-53, Article 53

2023

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RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer

Cancer research (Chicago, Ill.), 2006-07, Vol.66 (13), p.6512-6520

2006

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Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells

Blood cancer journal (New York), 2021-05, Vol.11 (5), p.98-98, Article 98

2021

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Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM)

Blood cancer journal (New York), 2024-02, Vol.14 (1), p.25-25, Article 25

2024

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Potent Inhibition of Platelet-Derived Growth Factor-Induced Responses in Vascular Smooth Muscle Cells by BMS-354825 (Dasatinib)

Molecular pharmacology, 2006-05, Vol.69 (5), p.1527-1533

2006

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Clinical experience with the BCL2‐inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies

American journal of hematology, 2018-03, Vol.93 (3), p.401-407

2018

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Efficacy of CDK9 inhibition in therapy of post-myeloproliferative neoplasm (MPN) secondary (s) AML cells

Blood cancer journal (New York), 2022-01, Vol.12 (1), p.23-23, Article 23

2022

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Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells

Cancer biology & therapy, 2009-05, Vol.8 (10), p.939-950

2009

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Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing

PloS one, 2010-09, Vol.5 (9), p.e13020

2010

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Microtubule-targeted anticancer agents and apoptosis

Epigenetic and Chromatin Modifiers As Targeted Therapy of Hematologic Malignancies

Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia

Phase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells

Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib

Dual PI3K/AKT/mTOR inhibitor BEZ235 synergistically enhances the activity of JAK2 inhibitor against cultured and primary human myeloproliferative neoplasm cells

Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish

Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)

Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells

EVI1 dysregulation: impact on biology and therapy of myeloid malignancies

A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas

p53 Acetylation Is Crucial for Its Transcription-independent Proapoptotic Functions

Anoikis, Initiated by Mcl-1 Degradation and Bim Induction, Is Deregulated during Oncogenesis

Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1

RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer

Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells

Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM)

Potent Inhibition of Platelet-Derived Growth Factor-Induced Responses in Vascular Smooth Muscle Cells by BMS-354825 (Dasatinib)

Clinical experience with the BCL2‐inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies

Efficacy of CDK9 inhibition in therapy of post-myeloproliferative neoplasm (MPN) secondary (s) AML cells

Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells

Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing

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