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Adaptive clinical trials: the promise and the caution

Journal of clinical oncology, 2011-02, Vol.29 (6), p.606-609

Berry, Donald A

2011

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A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody

Alzheimer's research & therapy, 2021-04, Vol.13 (1), p.80-80, Article 80

2021

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Lumpectomy Plus Tamoxifen With or Without Irradiation in Women Age 70 Years or Older With Early Breast Cancer: Long-Term Follow-Up of CALGB 9343

Journal of clinical oncology, 2013-07, Vol.31 (19), p.2382-2387

2013

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Impact of the addition of carboplatin and/or bevacizumab to neoadjuvant once-per-week paclitaxel followed by dose-dense doxorubicin and cyclophosphamide on pathologic complete response rates in stage II to III triple-negative breast cancer: CALGB 40603 (Alliance)

Journal of clinical oncology, 2015-01, Vol.33 (1), p.13-21

2015

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Addressing overdiagnosis and overtreatment in cancer: a prescription for change

The lancet oncology, 2014-05, Vol.15 (6), p.e234-e242

2014

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Bayesian hierarchical modeling of patient subpopulations: Efficient designs of Phase II oncology clinical trials

Clinical trials (London, England), 2013-10, Vol.10 (5), p.720-734

2013

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Pathologic Complete Response Predicts Recurrence-Free Survival More Effectively by Cancer Subset: Results From the I-SPY 1 TRIAL—CALGB 150007/150012, ACRIN 6657

Journal of clinical oncology, 2012-09, Vol.30 (26), p.3242-3249

2012

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The Decrease in Breast-Cancer Incidence in 2003 in the United States

The New England journal of medicine, 2007-04, Vol.356 (16), p.1670-1674

2007

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A cost/benefit analysis of clinical trial designs for COVID-19 vaccine candidates

PloS one, 2020-12, Vol.15 (12), p.e0244418-e0244418

2020

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Development and validation of a prognostic 40-day mortality risk model among hospitalized patients with COVID-19

PloS one, 2021-07, Vol.16 (7), p.e0255228-e0255228

2021

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High Risk of Recurrence for Patients With Breast Cancer Who Have Human Epidermal Growth Factor Receptor 2–Positive, Node-Negative Tumors 1 cm or Smaller

Journal of clinical oncology, 2009-12, Vol.27 (34), p.5700-5706

2009

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Effect of Screening and Adjuvant Therapy on Mortality from Breast Cancer

The New England journal of medicine, 2005-10, Vol.353 (17), p.1784-1792

2005

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Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer

Clinical cancer research, 2021-02, Vol.27 (4), p.1174-1183

2021

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HER2 and Response to Paclitaxel in Node-Positive Breast Cancer

The New England journal of medicine, 2007-10, Vol.357 (15), p.1496-1506

2007

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Consistency of efficacy results across various clinical measures and statistical methods in the lecanemab phase 2 trial of early Alzheimer's disease

Alzheimer's research & therapy, 2022-12, Vol.14 (1), p.182-182, Article 182

2022

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Adaptive clinical trials in oncology

Nature reviews. Clinical oncology, 2012-04, Vol.9 (4), p.199-207

Berry, Donald A

2012

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Vaccination With Patient-Specific Tumor-Derived Antigen in First Remission Improves Disease-Free Survival in Follicular Lymphoma

Journal of clinical oncology, 2011-07, Vol.29 (20), p.2787-2794

2011

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Toxicity of Older and Younger Patients Treated With Adjuvant Chemotherapy for Node-Positive Breast Cancer: The Cancer and Leukemia Group B Experience

Journal of clinical oncology, 2007-08, Vol.25 (24), p.3699-3704

2007

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The Brave New World of clinical cancer research: Adaptive biomarker-driven trials integrating clinical practice with clinical research

Molecular oncology, 2015-05, Vol.9 (5), p.951-959

Berry, Donald A.

2015

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A guide to drug discovery: Bayesian clinical trials

Nature reviews. Drug discovery, 2006-02, Vol.5 (1), p.27-36

Berry, Donald A

2006

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Design of a Bayesian adaptive phase 2 proof-of-concept trial for BAN2401, a putative disease-modifying monoclonal antibody for the treatment of Alzheimer's disease

Alzheimer's & dementia : translational research & clinical interventions, 2016-01, Vol.2 (1), p.1-12

2016

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MDM2 Promotes Cell Motility and Invasiveness by Regulating E-Cadherin Degradation

Molecular and Cellular Biology, 2006-10, Vol.26 (19), p.7269-7282

2006

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Adaptive clinical trials: the promise and the caution

A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody

Lumpectomy Plus Tamoxifen With or Without Irradiation in Women Age 70 Years or Older With Early Breast Cancer: Long-Term Follow-Up of CALGB 9343

Impact of the addition of carboplatin and/or bevacizumab to neoadjuvant once-per-week paclitaxel followed by dose-dense doxorubicin and cyclophosphamide on pathologic complete response rates in stage II to III triple-negative breast cancer: CALGB 40603 (Alliance)

Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials

Addressing overdiagnosis and overtreatment in cancer: a prescription for change

Bayesian hierarchical modeling of patient subpopulations: Efficient designs of Phase II oncology clinical trials

A randomized placebo‐controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis

Pathologic Complete Response Predicts Recurrence-Free Survival More Effectively by Cancer Subset: Results From the I-SPY 1 TRIAL—CALGB 150007/150012, ACRIN 6657

The Decrease in Breast-Cancer Incidence in 2003 in the United States

A cost/benefit analysis of clinical trial designs for COVID-19 vaccine candidates

Development and validation of a prognostic 40-day mortality risk model among hospitalized patients with COVID-19

High Risk of Recurrence for Patients With Breast Cancer Who Have Human Epidermal Growth Factor Receptor 2–Positive, Node-Negative Tumors 1 cm or Smaller

Effect of Screening and Adjuvant Therapy on Mortality from Breast Cancer

Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer

HER2 and Response to Paclitaxel in Node-Positive Breast Cancer

Consistency of efficacy results across various clinical measures and statistical methods in the lecanemab phase 2 trial of early Alzheimer's disease

Adaptive clinical trials in oncology

Vaccination With Patient-Specific Tumor-Derived Antigen in First Remission Improves Disease-Free Survival in Follicular Lymphoma

Toxicity of Older and Younger Patients Treated With Adjuvant Chemotherapy for Node-Positive Breast Cancer: The Cancer and Leukemia Group B Experience

The Brave New World of clinical cancer research: Adaptive biomarker-driven trials integrating clinical practice with clinical research

A guide to drug discovery: Bayesian clinical trials

Design of a Bayesian adaptive phase 2 proof-of-concept trial for BAN2401, a putative disease-modifying monoclonal antibody for the treatment of Alzheimer's disease

Randomized Trial of Dose-Dense Versus Conventionally Scheduled and Sequential Versus Concurrent Combination Chemotherapy as Postoperative Adjuvant Treatment of Node-Positive Primary Breast Cancer: First Report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741

MDM2 Promotes Cell Motility and Invasiveness by Regulating E-Cadherin Degradation

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