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Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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Synthesis and Activity of Analogues of SB-219383: Novel Potent Inhibitors of Bacterial Tyrosyl tRNA Synthetase

The Journal of Antibiotics, 2000/11/25, Vol.53(11), pp.1282-1292

2000

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Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (15), p.3937-3941

2004

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Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-Positive antibacterial activity

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (4), p.665-668

2003

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Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-Positive antibacterial activity

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (7), p.1265-1268

2003

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Inhibitors of bacterial tyrosyl tRNA synthetase: synthesis of four stereoisomeric analogues of the natural product SB-219383

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (16), p.1811-1814

2000

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Potent synthetic inhibitors of tyrosyl tRNA synthetase derived from C-pyranosyl analogues of SB-219383

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (5), p.715-718

2001

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Inhibitors of Bacterial Tyrosyl tRNA Synthetase: Synthesis of Carbocyclic Analogues of the Natural Product SB-219383

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (18), p.2499-2502

2001

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Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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Lewis-acid catalysed arylation of the hydroxyamino sugar moiety of the natural product SB-219383

Perkin 1 : an international journal of organic and bio-organic chemistry, 2001-10 (20), p.2521-2523

2001

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Interaction of tyrosyl aryl dipeptides with S. aureus tyrosyl tRNA synthetase: Inhibition and crystal structure of a complex

Bioorganic & medicinal chemistry letters, 1999-10, Vol.9 (19), p.2859-2862

1999

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Synthesis of a selective alpha-2A adrenoceptor antagonist, BRL 48962, and its characterization at cloned human alpha-adrenoceptors

Bioorganic & medicinal chemistry, 1995-12, Vol.3 (12), p.1693-1698

1995

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Epoxy ring-opening reactions of endo- and exo-3,4-epoxy-6-azabicyclo[3.2.0] heptan-7-ones

Journal of the Chemical Society, Perkin Transactions 1, 1980, p.690

1980

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Determination of the configuration and conformation of some epoxybicycloalkanones using the epoxide ring current effect

Journal of the Chemical Society, Perkin Transactions 2, 1978 (12), p.1205

1978

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Addition of Vinylketenes to Enamines. A Method for the Preparation of 6,6-Dialkylcyclohexa-2,4-dienones and 4,4-Dialkyl-2-vinylcyclobutenones

Helvetica chimica acta, 1982-11, Vol.65 (7), p.2230-2241

1982

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Recommended Work-up Procedure for Reductions Employing Tri-n-butyltin Hydride

Synthesis (Stuttgart), 1979, Vol.1979 (6), p.471-472

1979

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ChemInform Abstract: Inhibitors of Bacterial Tyrosyl tRNA Synthetase: Synthesis of Carbocyclic Analogues of the Natural Product SB-219383

ChemInform, 2002-02, Vol.33 (6), p.no-no

2002

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ChemInform Abstract: Inhibitors of Bacterial Tyrosyl tRNA Synthetase: Synthesis of Four Stereoisomeric Analogues of the Natural Product SB-219383

ChemInform, 2000-11, Vol.31 (47), p.no-no

2000

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ChemInform Abstract: Synthesis and Activity of Analogues of SB-219383: Novel Potent Inhibitors of Bacterial Tyrosyl tRNA Synthetase

ChemInform, 2001-04, Vol.32 (16), p.no-no

2001

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The role of mixotrophic protists in the biological carbon pump

Biogeosciences, 2014-02, Vol.11 (4), p.995-1005

2014

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Early postoperative decrease of albumin is an independent predictor of major complications after oncological esophagectomy: A multicenter study

Journal of surgical oncology, 2021-02, Vol.123 (2), p.462-469

2021

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Neoadjuvant Chemoradiotherapy Versus Chemotherapy for the Treatment of Locally Advanced Esophageal Adenocarcinoma in the European Multicenter ENSURE Study

Annals of surgery, 2023-11

2023

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Imaging markers of small vessel disease and brain frailty, and outcomes in acute stroke

Neurology, 2020-02, Vol.94 (5)

2020

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Permanent grasslands in Europe: Land use change and intensification decrease their multifunctionality

Agriculture, ecosystems & environment, 2022-06, Vol.330, p.107891, Article 107891

2022

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Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Synthesis and Activity of Analogues of SB-219383: Novel Potent Inhibitors of Bacterial Tyrosyl tRNA Synthetase

Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues

Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-Positive antibacterial activity

Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-Positive antibacterial activity

Inhibitors of bacterial tyrosyl tRNA synthetase: synthesis of four stereoisomeric analogues of the natural product SB-219383

Potent synthetic inhibitors of tyrosyl tRNA synthetase derived from C-pyranosyl analogues of SB-219383

Inhibitors of Bacterial Tyrosyl tRNA Synthetase: Synthesis of Carbocyclic Analogues of the Natural Product SB-219383

Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Lewis-acid catalysed arylation of the hydroxyamino sugar moiety of the natural product SB-219383

Interaction of tyrosyl aryl dipeptides with S. aureus tyrosyl tRNA synthetase: Inhibition and crystal structure of a complex

Synthesis of a selective alpha-2A adrenoceptor antagonist, BRL 48962, and its characterization at cloned human alpha-adrenoceptors

Epoxy ring-opening reactions of endo- and exo-3,4-epoxy-6-azabicyclo[3.2.0] heptan-7-ones

Determination of the configuration and conformation of some epoxybicycloalkanones using the epoxide ring current effect

Addition of Vinylketenes to Enamines. A Method for the Preparation of 6,6-Dialkylcyclohexa-2,4-dienones and 4,4-Dialkyl-2-vinylcyclobutenones

Recommended Work-up Procedure for Reductions Employing Tri-n-butyltin Hydride

ChemInform Abstract: Inhibitors of Bacterial Tyrosyl tRNA Synthetase: Synthesis of Carbocyclic Analogues of the Natural Product SB-219383

ChemInform Abstract: Inhibitors of Bacterial Tyrosyl tRNA Synthetase: Synthesis of Four Stereoisomeric Analogues of the Natural Product SB-219383

ChemInform Abstract: Synthesis and Activity of Analogues of SB-219383: Novel Potent Inhibitors of Bacterial Tyrosyl tRNA Synthetase

The role of mixotrophic protists in the biological carbon pump

Early postoperative decrease of albumin is an independent predictor of major complications after oncological esophagectomy: A multicenter study

Neoadjuvant Chemoradiotherapy Versus Chemotherapy for the Treatment of Locally Advanced Esophageal Adenocarcinoma in the European Multicenter ENSURE Study

Imaging markers of small vessel disease and brain frailty, and outcomes in acute stroke

Permanent grasslands in Europe: Land use change and intensification decrease their multifunctionality

Individual risk calculator to predict lymph node metastases in patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study

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