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Drug attrition during pre-clinical and clinical development: Understanding and managing drug-induced cardiotoxicity

Pharmacology & therapeutics (Oxford), 2013-06, Vol.138 (3), p.470-484

2013

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Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients: A novel approach for treating diabetic neuropathy?

Journal of clinical lipidology, 2015-07, Vol.9 (4), p.568-575

2015

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Differential effects of fenofibrate and extended-release niacin on high-density lipoprotein particle size distribution and cholesterol efflux capacity in dyslipidemic patients

Journal of clinical lipidology, 2013-09, Vol.7 (5), p.414-422

2013

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Pharmacogenomic determinants of the cardiovascular effects of dalcetrapib

Circulation. Cardiovascular genetics, 2015-04, Vol.8 (2), p.372-382

2015

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First-in-man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin

Journal of cardiovascular pharmacology, 2015-06, Vol.65 (6), p.611-619

2015

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Statin-Induced Decrease in ATP-Binding Cassette Transporter A1 Expression via microRNA33 Induction may Counteract Cholesterol Efflux to High-Density Lipoprotein

Cardiovascular drugs and therapy, 2015-02, Vol.29 (1), p.7-14

2015

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Red Blood Cell Membrane Cholesterol May Be a Key Regulator of Sickle Cell Disease Microvascular Complications

Membranes (Basel), 2022-11, Vol.12 (11), p.1134

2022

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Biological variation of established and novel biomarkers for atherosclerosis: Results from a prospective, parallel-group cohort study

Clinica chimica acta, 2015-07, Vol.447, p.16-22

2015

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Clinical benefit from pharmacological elevation of high-density lipoprotein cholesterol: meta-regression analysis

Heart (British Cardiac Society), 2015-06, Vol.101 (11), p.847-853

2015

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Development of CER-001: Preclinical Dose Selection Through to Phase I Clinical Findings

Clinical drug investigation, 2017-05, Vol.37 (5), p.483-491

2017

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Adenylyl Cyclase 9 Polymorphisms Reveal Potential Link to HDL Function and Cardiovascular Events in Multiple Pathologies: Potential Implications in Sickle Cell Disease

Cardiovascular Drugs and Therapy, 2015-12, Vol.29 (6), p.563-572

2015

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Fenofibrate and extended-release niacin improve the endothelial protective effects of HDL in patients with metabolic syndrome

Vascular pharmacology, 2015-11, Vol.74, p.80-86

2015

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STATIN–INDUCED DECREASE IN ABCA1 EXPRESSION VIA MIR33 INDUCTION MAY COUNTERACT CHOLESTEROL EFFLUX BY HIGH–DENSITY LIPOPROTEINS RAISED WITH THE CHOLESTERYL ESTER TRANSFER PROTEIN MODULATOR DALCETRAPIB

Journal of the American College of Cardiology, 2013-03, Vol.61 (10), p.E2032-E2032

2013

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Xanthophylls, Phytosterols and Pre-β1-HDL are Differentially Affected by Fenofibrate and Niacin HDL-Raising in a Cross-Over Study

Lipids, 2013-12, Vol.48 (12), p.1185-1196

2013

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Xanthophylls, Phytosterols and Pre-[beta]1-HDL are Differentially Affected by Fenofibrate and Niacin HDL-Raising in a Cross-Over Study

Lipids, 2013-12, Vol.48 (12), p.1185

2013

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Potential Signal Transduction Regulation by HDL of the β2-Adrenergic Receptor Pathway. Implications in Selected Pathological Situations

Archives of medical research, 2015-07, Vol.46 (5), p.361-371

2015

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Frequency of creatine kinase elevation during treatment with fluvastatin

The American journal of cardiology, 2002-01, Vol.89 (2), p.231-233

2002

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Comparison of fluvastatin versus pravastatin treatment of primary hypercholesterolemia

The American journal of cardiology, 1995-07, Vol.76 (1), p.54A-56A

1995

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The ASPIC trial: Telematics-assisted management of a multicenter clinical trial using a network of laptop personal computers

Controlled clinical trials, 1989, Vol.10 (3), p.341-341

1989

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Effects of fluvastatin on cardiac events in renal transplant patients: ALERT (Assessment of Lescol in Renal Transplantation) study design and baseline data

Journal of cardiovascular risk, 2001-04, Vol.8 (2), p.63-71

2001

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The Lescol ® Intervention Prevention Study (LIPS): a double-blind, placebo-controlled, randomized trial of the long-term effects of fluvastatin after successful transcatheter therapy in patients with coronary heart disease

International journal of cardiovascular interventions, 2001, Vol.4 (4), p.165-172

2001

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Effects of Fluvastatin on Cardiac Events in Renal Transplant Patients: ALERT (Assessment of Lescol® in Renal Transplantation) Study Design and Baseline Data

European journal of cardiovascular prevention and rehabilitation, 2001-04, Vol.8 (2), p.63-71

2001

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Drug attrition during pre-clinical and clinical development: Understanding and managing drug-induced cardiotoxicity

Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients: A novel approach for treating diabetic neuropathy?

Differential effects of fenofibrate and extended-release niacin on high-density lipoprotein particle size distribution and cholesterol efflux capacity in dyslipidemic patients

Pharmacogenomic determinants of the cardiovascular effects of dalcetrapib

First-in-man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin

Statin-Induced Decrease in ATP-Binding Cassette Transporter A1 Expression via microRNA33 Induction may Counteract Cholesterol Efflux to High-Density Lipoprotein

Red Blood Cell Membrane Cholesterol May Be a Key Regulator of Sickle Cell Disease Microvascular Complications

Biological variation of established and novel biomarkers for atherosclerosis: Results from a prospective, parallel-group cohort study

Clinical benefit from pharmacological elevation of high-density lipoprotein cholesterol: meta-regression analysis

Development of CER-001: Preclinical Dose Selection Through to Phase I Clinical Findings

Adenylyl Cyclase 9 Polymorphisms Reveal Potential Link to HDL Function and Cardiovascular Events in Multiple Pathologies: Potential Implications in Sickle Cell Disease

Fenofibrate and extended-release niacin improve the endothelial protective effects of HDL in patients with metabolic syndrome

STATIN–INDUCED DECREASE IN ABCA1 EXPRESSION VIA MIR33 INDUCTION MAY COUNTERACT CHOLESTEROL EFFLUX BY HIGH–DENSITY LIPOPROTEINS RAISED WITH THE CHOLESTERYL ESTER TRANSFER PROTEIN MODULATOR DALCETRAPIB

Xanthophylls, Phytosterols and Pre-β1-HDL are Differentially Affected by Fenofibrate and Niacin HDL-Raising in a Cross-Over Study

Xanthophylls, Phytosterols and Pre-[beta]1-HDL are Differentially Affected by Fenofibrate and Niacin HDL-Raising in a Cross-Over Study

Potential Signal Transduction Regulation by HDL of the β2-Adrenergic Receptor Pathway. Implications in Selected Pathological Situations

Frequency of creatine kinase elevation during treatment with fluvastatin

Comparison of fluvastatin versus pravastatin treatment of primary hypercholesterolemia

The ASPIC trial: Telematics-assisted management of a multicenter clinical trial using a network of laptop personal computers

Effects of fluvastatin on cardiac events in renal transplant patients: ALERT (Assessment of Lescol in Renal Transplantation) study design and baseline data

The Lescol ® Intervention Prevention Study (LIPS): a double-blind, placebo-controlled, randomized trial of the long-term effects of fluvastatin after successful transcatheter therapy in patients with coronary heart disease

Effects of Fluvastatin on Cardiac Events in Renal Transplant Patients: ALERT (Assessment of Lescol® in Renal Transplantation) Study Design and Baseline Data

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