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Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992

Molecular pharmacology, 2018-08, Vol.94 (2), p.926-937

2018

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Classics in Chemical Neuroscience: Xanomeline

ACS chemical neuroscience, 2017-03, Vol.8 (3), p.435-443

2017

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The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

PLoS pathogens, 2020-01, Vol.16 (1), p.e1008134-e1008134

2020

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Brain-Penetrant Macrocycles: Design Considerations, Future Prospects, and Call for Papers

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.7665-7667

2024

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Sleeping Beauty-Mediated Somatic Mutagenesis Implicates CSF1 in the Formation of High-Grade Astrocytomas

Cancer research (Chicago, Ill.), 2010-05, Vol.70 (9), p.3557-3565

2010

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Classics in Chemical Neuroscience: Memantine

ACS chemical neuroscience, 2017-09, Vol.8 (9), p.1823-1829

2017

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Alkylation of NH-sulfoximines under Mitsunobu-type conditions

Organic & biomolecular chemistry, 2023-06, Vol.21 (25), p.5181-5184

2023

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Alkylation of N H-sulfoximines under Mitsunobu-type conditions

Organic & biomolecular chemistry, 2023-06, Vol.21 (25), p.5181-5184

2023

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2B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery

Journal of medicinal chemistry, 2023-08, Vol.66 (16), p.11027-11039

2023

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Preparation of Unsymmetrical 1,2,4,5-Tetrazines via a Mild Suzuki Cross-Coupling Reaction

Organic letters, 2017-10, Vol.19 (20), p.5693-5696

2017

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DARK Classics in Chemical Neuroscience: Carfentanil

ACS chemical neuroscience, 2020-12, Vol.11 (23), p.3955-3967

2020

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Development of a Selective and High Affinity Radioligand, [ 3 H]VU6013720, for the M 4 Muscarinic Receptor

Molecular pharmacology, 2023-11, Vol.104 (5), p.195

2023

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The Muscarinic Acetylcholine Receptor M 5 : Therapeutic Implications and Allosteric Modulation

ACS chemical neuroscience, 2019-03, Vol.10 (3), p.1025-1034

2019

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Synthesis of Substituted 6,7-Dihydro‑5H‑pyrrolo[2,3‑c]pyridazines/pyrazines via Catalyst-Free Tandem Hydroamination–Aromatic Substitution

Journal of organic chemistry, 2020-05, Vol.85 (9), p.6123-6130

2020

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Synthesis of Substituted 6,7-Dihydro-5 H -pyrrolo[2,3- c ]pyridazines/pyrazines via Catalyst-Free Tandem Hydroamination-Aromatic Substitution

Journal of organic chemistry, 2020-05, Vol.85 (9), p.6123-6130

2020

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Identification of Potent, Selective, and Peripherally Restricted Serotonin Receptor 2B Antagonists from a High-Throughput Screen

Assay and drug development technologies, 2023-04, Vol.21 (3), p.89

2023

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Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M1

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128193-128193, Article 128193

2021

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DARK Classics in Chemical Neuroscience: Methaqualone

ACS chemical neuroscience, 2023-02, Vol.14 (3), p.340-350

2023

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Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M 1

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128193

2021

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Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M4 muscarinic acetylcholine receptor

Bioorganic & medicinal chemistry letters, 2022-01, Vol.56, p.128479-128479, Article 128479

2022

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Effects of N‑Substitutions on the Tetrahydroquinoline (THQ) Core of Mixed-Efficacy μ‑Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Ligands

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4985-4998

2016

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Dual Pharmacophores Explored via Structure–Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand Design

Journal of medicinal chemistry, 2019-04, Vol.62 (8), p.4193-4203

2019

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Evaluation of the Indazole Analogs of 5‑MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists

ACS medicinal chemistry letters, 2024-02, Vol.15 (2), p.302-309

2024

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lin-35/Rb and the CoREST ortholog spr-1 coordinately regulate vulval morphogenesis and gonad development in C. elegans

Developmental biology, 2007-02, Vol.302 (2), p.448-462

2007

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Opioid Peptidomimetics: Leads for the Design of Bioavailable Mixed Efficacy μ Opioid Receptor (MOR) Agonist/δ Opioid Receptor (DOR) Antagonist Ligands

Journal of medicinal chemistry, 2013-03, Vol.56 (5), p.2139-2149

2013

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Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992

Classics in Chemical Neuroscience: Xanomeline

The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

Brain-Penetrant Macrocycles: Design Considerations, Future Prospects, and Call for Papers

Sleeping Beauty-Mediated Somatic Mutagenesis Implicates CSF1 in the Formation of High-Grade Astrocytomas

Classics in Chemical Neuroscience: Memantine

Alkylation of NH-sulfoximines under Mitsunobu-type conditions

Alkylation of N H-sulfoximines under Mitsunobu-type conditions

2B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery

Preparation of Unsymmetrical 1,2,4,5-Tetrazines via a Mild Suzuki Cross-Coupling Reaction

DARK Classics in Chemical Neuroscience: Carfentanil

Development of a Selective and High Affinity Radioligand, [ 3 H]VU6013720, for the M 4 Muscarinic Receptor

The Muscarinic Acetylcholine Receptor M 5 : Therapeutic Implications and Allosteric Modulation

Synthesis of Substituted 6,7-Dihydro‑5H‑pyrrolo[2,3‑c]pyridazines/pyrazines via Catalyst-Free Tandem Hydroamination–Aromatic Substitution

Synthesis of Substituted 6,7-Dihydro-5 H -pyrrolo[2,3- c ]pyridazines/pyrazines via Catalyst-Free Tandem Hydroamination-Aromatic Substitution

Identification of Potent, Selective, and Peripherally Restricted Serotonin Receptor 2B Antagonists from a High-Throughput Screen

Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M1

DARK Classics in Chemical Neuroscience: Methaqualone

Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M 1

Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M4 muscarinic acetylcholine receptor

Effects of N‑Substitutions on the Tetrahydroquinoline (THQ) Core of Mixed-Efficacy μ‑Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Ligands

Dual Pharmacophores Explored via Structure–Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand Design

Evaluation of the Indazole Analogs of 5‑MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists

lin-35/Rb and the CoREST ortholog spr-1 coordinately regulate vulval morphogenesis and gonad development in C. elegans

Opioid Peptidomimetics: Leads for the Design of Bioavailable Mixed Efficacy μ Opioid Receptor (MOR) Agonist/δ Opioid Receptor (DOR) Antagonist Ligands

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