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Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases

Annual review of pharmacology and toxicology, 2016-01, Vol.56 (1), p.229-249

2016

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Bioenergetic profiling of zebrafish embryonic development

PloS one, 2011-09, Vol.6 (9), p.e25652-e25652

2011

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Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma

Nature communications, 2019-03, Vol.10 (1), p.1296-15, Article 1296

2019

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A high-throughput respirometric assay for mitochondrial biogenesis and toxicity

Analytical biochemistry, 2010-09, Vol.404 (1), p.75-81

2010

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Mitochondrial C3a Receptor Activation in Oxidatively Stressed Epithelial Cells Reduces Mitochondrial Respiration and Metabolism

Frontiers in immunology, 2021-03, Vol.12, p.628062-628062

2021

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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

Cell reports (Cambridge), 2019-08, Vol.28 (7), p.1879-1893.e7

2019

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Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1)

The Journal of biological chemistry, 2016-05, Vol.291 (20), p.10836-10846

2016

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Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity

Nature biomedical engineering, 2020-04, Vol.4 (4), p.446

2020

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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

Cell metabolism, 2018-01, Vol.27 (1), p.85-100.e8

2018

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Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline

Free radical biology & medicine, 2016-08, Vol.97, p.418-426

2016

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Formoterol Restores Mitochondrial and Renal Function after Ischemia-Reperfusion Injury

Journal of the American Society of Nephrology, 2014-06, Vol.25 (6), p.1157-1162

2014

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Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases

Journal of medicinal chemistry, 2016-12, Vol.59 (23), p.10411-10434

2016

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Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning

Biochimica et biophysica acta, 2015-02, Vol.1853 (2), p.348-360

2015

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The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis

The Journal of pharmacology and experimental therapeutics, 2012-07, Vol.342 (1), p.106

2012

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A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome

Cell reports (Cambridge), 2018-11, Vol.25 (6), p.1469-1484.e5

2018

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A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102336, Article 102336

2022

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Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury

Kidney international, 2015-12, Vol.88 (6), p.1336-1344

2015

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Systematic Study of Mitochondrial Toxicity of Environmental Chemicals Using Quantitative High Throughput Screening

Chemical research in toxicology, 2013-09, Vol.26 (9), p.1323-1332

2013

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Statin‐dependent modulation of mitochondrial metabolism in cancer cells is independent of cholesterol content

The FASEB journal, 2019-07, Vol.33 (7), p.8186-8201

2019

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Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform

Journal of bioenergetics and biomembranes, 2012-08, Vol.44 (4), p.421-437

2012

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ABCD1 deletion‐induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy

Journal of neurochemistry, 2015-05, Vol.133 (3), p.380-396

2015

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Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol

Scientific reports, 2017-09, Vol.7 (1), p.10578-11, Article 10578

2017

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5-HT1F receptor regulates mitochondrial homeostasis and its loss potentiates acute kidney injury and impairs renal recovery

American journal of physiology. Renal physiology, 2018-10, Vol.315 (4), p.F1119-F1128

2018

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Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrests Growth of Gynecologic Cancers

Frontiers in pharmacology, 2020-05, Vol.11, p.577-577

2020

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TGF-β1 stimulates mitochondrial oxidative phosphorylation and generation of reactive oxygen species in cultured mouse podocytes, mediated in part by the mTOR pathway

American journal of physiology. Renal physiology, 2013-11, Vol.305 (10), p.F1477-F1490

2013

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Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases

Bioenergetic profiling of zebrafish embryonic development

Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma

A high-throughput respirometric assay for mitochondrial biogenesis and toxicity

Mitochondrial C3a Receptor Activation in Oxidatively Stressed Epithelial Cells Reduces Mitochondrial Respiration and Metabolism

Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1)

Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity

CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline

Formoterol Restores Mitochondrial and Renal Function after Ischemia-Reperfusion Injury

Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases

Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning

The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis

A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome

A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria

Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury

Systematic Study of Mitochondrial Toxicity of Environmental Chemicals Using Quantitative High Throughput Screening

Statin‐dependent modulation of mitochondrial metabolism in cancer cells is independent of cholesterol content

Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform

ABCD1 deletion‐induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy

Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol

5-HT1F receptor regulates mitochondrial homeostasis and its loss potentiates acute kidney injury and impairs renal recovery

Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrests Growth of Gynecologic Cancers

TGF-β1 stimulates mitochondrial oxidative phosphorylation and generation of reactive oxygen species in cultured mouse podocytes, mediated in part by the mTOR pathway

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