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Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines

Bioorganic & medicinal chemistry, 2009-07, Vol.17 (13), p.4406-4419

2009

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Synthesis and cytotoxic evaluation of benzoxazole/benzothiazole-2-imino-coumarin hybrids and their coumarin analogues as potential anticancer agents

Pharmazie, 2019-11, Vol.74 (11), p.648-657

2019

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Studies of the inhibitory activities of tiopronin and mercaptosuccinic acid on glutathione peroxidase and their cytotoxic and antioxidant properties

Pharmazie, 2019-09, Vol.74 (9), p.536-542

2019

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Evaluation of the in vitro anticancer, antimicrobial and antioxidant activities of some Yemeni plants used in folk medicine

Pharmazie, 2009-04, Vol.64 (4), p.260-268

2009

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Cytotoxic activities of hydroxyethyl piperazine-based σ receptor ligands on cancer cells alone and in combination with melphalan, PB28 and haloperidol

Pharmazie, 2014-12, Vol.69 (12), p.917-922

2014

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Synthesis and X-ray Crystal Structure of trans,cis-[Pt(OAc)2I2(en)]: A Novel Type of Cisplatin Analog That Can Be Photolyzed by Visible Light to DNA-Binding and Cytotoxic Species in Vitro

Journal of medicinal chemistry, 1996-06, Vol.39 (13), p.2499-2507

1996

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New synthetic route to [bis-1,2-(aminomethyl)benzene]dichloroplatinum(II) complexes, screening for cytotoxic activity in cisplatin-sensitive and resistant human cancer cell lines, and reaction with glutathione

Pharmazie, 2001-10, Vol.56 (10), p.763-769

2001

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Study of the anticancer potential of Yemeni plants used in folk medicine

Pharmazie, 2007-04, Vol.62 (4), p.305-307

2007

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Degradation and intermediates of diclofenac as instructive example for decomposition of recalcitrant pharmaceuticals by hydroxyl radicals generated with pulsed corona plasma in water

Journal of hazardous materials, 2018-01, Vol.342, p.651-660

2018

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Antimicrobial and cytotoxic abietane diterpenoids from the roots of Meriandera benghalensis (Roxb.) Benth

Pharmazie, 2009-09, Vol.64 (9), p.613-615

2009

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Effect of thiols exported by cancer cells on the stability and growth-inhibitory activity of Pt(IV) complexes

Journal of cancer research and clinical oncology, 1999-12, Vol.125 (12), p.690-696

1999

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Reversible and irreversible interactions of a cisplatin analog bearing a 1,2-diphenylethylenediamine ligand with plasma and plasma proteins in vitro

Drug metabolism and disposition, 1994-05, Vol.22 (3), p.419

1994

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Quantification of elastase-like activity in 13 human cancer cell lines and in an immortalized human epithelial cell line by RP-HPLC

Biological chemistry, 2003-05, Vol.384 (5), p.817

2003

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A Novel Approach to Preparing Water Soluble Prodrug Forms of Cisplatin Analogues Bearing Chelating Diamines

Journal of pharmaceutical sciences, 1995-07, Vol.84 (7), p.819-823

1995

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Electron-Transfer-Driven Trans-Ligand Labilization: A Novel Activation Mechanism for Pt(IV) Anticancer Complexes

Journal of the American Chemical Society, 1998-08, Vol.120 (32), p.8253-8254

1998

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Interactions of thiol-containing androgens with human placental aromatase

Journal of medicinal chemistry, 1989-01, Vol.32 (1), p.203-213

1989

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Photolysis of an iodoplatinum(IV) diamine complex to cytotoxic species by visible light

Anti-cancer drug design, 1996-03, Vol.11 (2), p.155

1996

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Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data

Anti-cancer drugs, 2006-01, Vol.17 (1), p.41-51

2006

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Relationships between Reduction Properties and Cancer Cell Growth Inhibitory Activities of cis-Dichloro- and cis-Diiodo-Pt(IV)-ethylenediamines

Archiv der Pharmazie (Weinheim), 1999-08, Vol.332 (8), p.279-285

1999

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Thiol-containing androgens as suicide substrates of aromatase

Journal of medicinal chemistry, 1985-06, Vol.28 (6), p.775-779

1985

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Relationships between the aqueous chemistry and the in vitro cytotoxic activities of mixed-amine cisplatin analogues

Biochemical pharmacology, 1992-06, Vol.43 (12), p.2609-2620

Bednarski, Patrick J.

1992

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Characterization of chemosensitivity and resistance of human cancer cell lines to platinum(II) versus platinum(IV) anticancer agents

Anti-cancer drugs, 2009-08, Vol.20 (7), p.559-572

2009

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4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of a screening library

MedChemComm, 2014, Vol.5 (2), p.203

2014

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Chemical stability, biological activity and cellular uptake of a cisplatin analogue having a 1,2-diarylethyleneamine ligand in cultures of human breast cancer cells

Journal of cancer research and clinical oncology, 1995, Vol.121 (1), p.31-38

1995

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4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of a screening libraryElectronic supplementary information (ESI) available: Synthesis and characterization data of inactive products. See DOI: 10.1039/c3md00252g

2014-01

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Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines

Synthesis and cytotoxic evaluation of benzoxazole/benzothiazole-2-imino-coumarin hybrids and their coumarin analogues as potential anticancer agents

Studies of the inhibitory activities of tiopronin and mercaptosuccinic acid on glutathione peroxidase and their cytotoxic and antioxidant properties

Evaluation of the in vitro anticancer, antimicrobial and antioxidant activities of some Yemeni plants used in folk medicine

Cytotoxic activities of hydroxyethyl piperazine-based σ receptor ligands on cancer cells alone and in combination with melphalan, PB28 and haloperidol

Synthesis and X-ray Crystal Structure of trans,cis-[Pt(OAc)2I2(en)]: A Novel Type of Cisplatin Analog That Can Be Photolyzed by Visible Light to DNA-Binding and Cytotoxic Species in Vitro

New synthetic route to [bis-1,2-(aminomethyl)benzene]dichloroplatinum(II) complexes, screening for cytotoxic activity in cisplatin-sensitive and resistant human cancer cell lines, and reaction with glutathione

Study of the anticancer potential of Yemeni plants used in folk medicine

Degradation and intermediates of diclofenac as instructive example for decomposition of recalcitrant pharmaceuticals by hydroxyl radicals generated with pulsed corona plasma in water

Antimicrobial and cytotoxic abietane diterpenoids from the roots of Meriandera benghalensis (Roxb.) Benth

Effect of thiols exported by cancer cells on the stability and growth-inhibitory activity of Pt(IV) complexes

Reversible and irreversible interactions of a cisplatin analog bearing a 1,2-diphenylethylenediamine ligand with plasma and plasma proteins in vitro

Quantification of elastase-like activity in 13 human cancer cell lines and in an immortalized human epithelial cell line by RP-HPLC

A Novel Approach to Preparing Water Soluble Prodrug Forms of Cisplatin Analogues Bearing Chelating Diamines

Electron-Transfer-Driven Trans-Ligand Labilization: A Novel Activation Mechanism for Pt(IV) Anticancer Complexes

Interactions of thiol-containing androgens with human placental aromatase

Photolysis of an iodoplatinum(IV) diamine complex to cytotoxic species by visible light

Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data

Relationships between Reduction Properties and Cancer Cell Growth Inhibitory Activities of cis-Dichloro- and cis-Diiodo-Pt(IV)-ethylenediamines

Thiol-containing androgens as suicide substrates of aromatase

Relationships between the aqueous chemistry and the in vitro cytotoxic activities of mixed-amine cisplatin analogues

Characterization of chemosensitivity and resistance of human cancer cell lines to platinum(II) versus platinum(IV) anticancer agents

4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of a screening library

Chemical stability, biological activity and cellular uptake of a cisplatin analogue having a 1,2-diarylethyleneamine ligand in cultures of human breast cancer cells

4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of a screening libraryElectronic supplementary information (ESI) available: Synthesis and characterization data of inactive products. See DOI: 10.1039/c3md00252g

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