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Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs

Science (American Association for the Advancement of Science), 1999-09, Vol.285 (5433), p.1573-1576

1999

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In Vitro and In Vivo Synergy of Fosmidomycin, a Novel Antimalarial Drug, with Clindamycin

Antimicrobial Agents and Chemotherapy, 2002-09, Vol.46 (9), p.2889-2894

2002

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Crystal Structure of 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase, a Crucial Enzyme in the Non-mevalonate Pathway of Isoprenoid Biosynthesis

The Journal of biological chemistry, 2002-02, Vol.277 (7), p.5378-5384

2002

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Highly Effective Serodiagnosis for Chagas' Disease

Clinical and Vaccine Immunology, 2010-10, Vol.17 (10), p.1598-1604

2010

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Functional characterization of GcpE, an essential enzyme of the non-mevalonate pathway of isoprenoid biosynthesis

FEBS letters, 2002-12, Vol.532 (3), p.432-436

2002

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Cell recognition by foot-and-mouth disease virus that lacks the RGD integrin-binding motif: flexibility in aphthovirus receptor usage

Journal of Virology, 2000-02, Vol.74 (4), p.1641-1647

2000

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LytB, a novel gene of the 2- C-methyl- D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli

FEBS letters, 2001-06, Vol.499 (1), p.37-40

2001

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Multiple Virulence Determinants of Foot-and-Mouth Disease Virus in Cell Culture

Journal of Virology, 1998-08, Vol.72 (8), p.6362-6372

1998

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GcpE Is Involved in the 2-C-Methyl-d-Erythritol 4-Phosphate Pathway of Isoprenoid Biosynthesis in Escherichia coli

Journal of Bacteriology, 2001-04, Vol.183 (8), p.2411-2416

2001

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Mycoplasma penetrans Is Capable of Activating Vγ9/Vδ2 T Cells While Other Human Pathogenic Mycoplasmas Fail To Do So

Infection and Immunity, 2004-08, Vol.72 (8), p.4881-4883

2004

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Development and performance evaluation of an In-House ELISA for the detection of group A rotavirus in diarrheal stool samples from children and domestic South American camelids

Journal of virological methods, 2022-03, Vol.301, p.114453-114453, Article 114453

2022

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Identification of ( E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human γδ T cells in Escherichia coli

FEBS letters, 2001-12, Vol.509 (2), p.317-322

2001

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Interaction of eukaryotic initiation factor eIF4B with the internal ribosome entry site of foot-and-mouth disease virus is independent of the polypyrimidine tract-binding protein

Journal of Virology, 1999-07, Vol.73 (7), p.6111-6113

1999

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Isolation of T-Cell Antigens by Using a Recombinant Protein Library and Its Application to the Identification of Novel Vaccine Candidates against Schistosomiasis

Infection and Immunity, 1999-07, Vol.67 (7), p.3383-3389

1999

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Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparum

FEBS letters, 2005-11, Vol.579 (28), p.6433-6438

2005

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LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis

FEBS letters, 2002-12, Vol.532 (3), p.437-440

2002

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Acyloxyalkyl ester prodrugs of FR900098 with improved in vivo anti-malarial activity

Bioorganic & medicinal chemistry letters, 2003-07, Vol.13 (13), p.2163-2166

2003

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Differentiation of human γδ T cells towards distinct memory phenotypes

Cellular immunology, 2002, Vol.218 (1), p.1-6

2002

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Characterization of the DMAE-modified juvenile excretory–secretory protein Juv-p120 of Litomosoides sigmodontis

Molecular and biochemical parasitology, 2011-04, Vol.176 (2), p.80-89

2011

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Differentiation of human gamma-delta T cells towards distinct memory phenotypes

Cellular immunology, 2002-07, Vol.218 (1-2), p.1-6

2002

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Cathepsin B of Schistosoma mansoni

The Journal of biological chemistry, 1996-01, Vol.271 (3), p.1717-1725

1996

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Diaryl ester prodrugs of fR900098 with improved in vivo antimalarial activity

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (6), p.833-835

2001

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Alkoxycarbonyloxyethyl Ester Prodrugs of FR900098 with Improved In Vivo Antimalarial Activity

Archiv der Pharmazie (Weinheim), 2005-07, Vol.338 (7), p.305-314

2005

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Tools for discovery of inhibitors of the 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: an approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa

FEMS microbiology letters, 2000-09, Vol.190 (2), p.329-333

2000

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Tools for discovery of inhibitors of the 1-deoxy- D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: an approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa

FEMS microbiology letters, 2000-09, Vol.190 (2), p.329-333

2000

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Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs

In Vitro and In Vivo Synergy of Fosmidomycin, a Novel Antimalarial Drug, with Clindamycin

Crystal Structure of 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase, a Crucial Enzyme in the Non-mevalonate Pathway of Isoprenoid Biosynthesis

Highly Effective Serodiagnosis for Chagas' Disease

Functional characterization of GcpE, an essential enzyme of the non-mevalonate pathway of isoprenoid biosynthesis

Cell recognition by foot-and-mouth disease virus that lacks the RGD integrin-binding motif: flexibility in aphthovirus receptor usage

LytB, a novel gene of the 2- C-methyl- D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli

Multiple Virulence Determinants of Foot-and-Mouth Disease Virus in Cell Culture

GcpE Is Involved in the 2-C-Methyl-d-Erythritol 4-Phosphate Pathway of Isoprenoid Biosynthesis in Escherichia coli

Mycoplasma penetrans Is Capable of Activating Vγ9/Vδ2 T Cells While Other Human Pathogenic Mycoplasmas Fail To Do So

Development and performance evaluation of an In-House ELISA for the detection of group A rotavirus in diarrheal stool samples from children and domestic South American camelids

Identification of ( E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human γδ T cells in Escherichia coli

Interaction of eukaryotic initiation factor eIF4B with the internal ribosome entry site of foot-and-mouth disease virus is independent of the polypyrimidine tract-binding protein

Isolation of T-Cell Antigens by Using a Recombinant Protein Library and Its Application to the Identification of Novel Vaccine Candidates against Schistosomiasis

Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparum

LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis

Acyloxyalkyl ester prodrugs of FR900098 with improved in vivo anti-malarial activity

Differentiation of human γδ T cells towards distinct memory phenotypes

Characterization of the DMAE-modified juvenile excretory–secretory protein Juv-p120 of Litomosoides sigmodontis

Differentiation of human gamma-delta T cells towards distinct memory phenotypes

Cathepsin B of Schistosoma mansoni

Diaryl ester prodrugs of fR900098 with improved in vivo antimalarial activity

Alkoxycarbonyloxyethyl Ester Prodrugs of FR900098 with Improved In Vivo Antimalarial Activity

Tools for discovery of inhibitors of the 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: an approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa

Tools for discovery of inhibitors of the 1-deoxy- D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: an approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa

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