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Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase)

British journal of cancer, 1997-01, Vol.75 (1), p.69-75

1997

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NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

Chemico-biological interactions, 2000-12, Vol.129 (1), p.77-97

2000

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Indolequinone Antitumor Agents: Correlation between Quinone Structure and Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase. Part 2

Journal of medicinal chemistry, 2001-09, Vol.44 (20), p.3311-3319

2001

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Indolequinone Antitumor Agents: Correlation between Quinone Structure, Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase, and in Vitro Cytotoxicity

Journal of medicinal chemistry, 1998-11, Vol.41 (24), p.4755-4766

1998

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Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines

Molecular pharmacology, 1995-09, Vol.48 (3), p.499

1995

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Arsenic exposure exacerbates atherosclerotic plaque formation and increases nitrotyrosine and leukotriene biosynthesis

Toxicology and applied pharmacology, 2004-11, Vol.201 (1), p.32-39

2004

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Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases

Cancer research (Chicago, Ill.), 1994-06, Vol.54 (12), p.3196-3201

1994

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Enzymology of bioreductive drug activation

British journal of cancer. Supplement, 1996-07, Vol.27, p.S1-S8

1996

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Novel Lavendamycin Analogues as Antitumor Agents: Synthesis, in Vitro Cytotoxicity, Structure−Metabolism, and Computational Molecular Modeling Studies with NAD(P)H:Quinone Oxidoreductase 1

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7733-7749

2005

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Topical delivery of 5-fluorouracil (5-Fu) by 3-alkylcarbonyl-5-Fu prodrugs

International journal of pharmaceutics, 2001-04, Vol.217 (1), p.127-137

2001

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Role of NAD(P)H:Quinone oxidoreductase (DT-diaphorase) in cytotoxicity and induction of DNA damage by streptonigrin

Biochemical pharmacology, 1996-03, Vol.51 (5), p.645-652

1996

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Arsenic Induces Peroxynitrite Generation and Cyclooxygenase-2 Protein Expression in Aortic Endothelial Cells: Possible Role in Atherosclerosis

Toxicology and applied pharmacology, 2002-10, Vol.184 (1), p.11-18

2002

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Novel quinolinequinone antitumor agents: Structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1)

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2195-2198

1999

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Transdermal delivery of theophylline from alcohol vehicles

International journal of pharmaceutics, 1998-09, Vol.171 (2), p.185-193

1998

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Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones

Molecular pharmacology, 1996-10, Vol.50 (4), p.728-735

1996

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Indolequinone antitumor agents: Relationship between quinone structure and rate of metabolism by recombinant human NQO1

Bioorganic & medicinal chemistry letters, 1998-03, Vol.8 (5), p.545-548

1998

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Transdermal delivery of 5-fluorouracil (5-FU) by 1-alkylcarbonyl-5-FU prodrugs

International journal of pharmaceutics, 1996-03, Vol.129 (1), p.203-210

1996

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Arsenic Exposure in Pregnant Mice Disrupts Placental Vasculogenesis and Causes Spontaneous Abortion

Toxicological sciences, 2007-09, Vol.99 (1), p.244-253

2007

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The estimation of relative water solubility for prodrugs that are unstable in water

International journal of pharmaceutics, 1993-05, Vol.93 (1), p.37-47

1993

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Topical delivery of 5-fluorouracil (5-FU) by 1,3-bisalkylcarbonyl-5-FU prodrugs

International journal of pharmaceutics, 2002, Vol.231 (1), p.43-49

2002

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Noncovalent binding of a mitomycin C metabolite, 2,7-diaminomitosene, to duplex DNA

Cancer letters, 1995-04, Vol.90 (2), p.133-138

1995

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Stability of sumatriptan succinate in extemporaneously prepared oral liquids

American journal of health-system pharmacy, 1997-07, Vol.54 (14), p.1619-1622

1997

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1,3-Bisalkylcarbonyl- and 3-Alkylcarbonyl-5-fluorouracil Prodrugs: Syntheses, Thermal, and Hydrolytic Stability

Drug development and industrial pharmacy, 1997, Vol.23 (6), p.517-525

1997

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1-Alkylcarbonyl-5-fluorouracil Prodrugs: Synthesis, Thermal and Hydrolytic Stability

Drug development and industrial pharmacy, 1996, Vol.22 (2), p.85-90

1996

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Structure of 3-acetyl-5-fluorouracil (5-FU) : implication for its rearrangements during hydrolysis and upon heating

Pharmaceutical research, 1993-06, Vol.10 (6), p.905-912

1993

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Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase)

NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

Indolequinone Antitumor Agents: Correlation between Quinone Structure and Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase. Part 2

Indolequinone Antitumor Agents: Correlation between Quinone Structure, Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase, and in Vitro Cytotoxicity

Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines

Arsenic exposure exacerbates atherosclerotic plaque formation and increases nitrotyrosine and leukotriene biosynthesis

Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases

Enzymology of bioreductive drug activation

Novel Lavendamycin Analogues as Antitumor Agents: Synthesis, in Vitro Cytotoxicity, Structure−Metabolism, and Computational Molecular Modeling Studies with NAD(P)H:Quinone Oxidoreductase 1

Topical delivery of 5-fluorouracil (5-Fu) by 3-alkylcarbonyl-5-Fu prodrugs

Role of NAD(P)H:Quinone oxidoreductase (DT-diaphorase) in cytotoxicity and induction of DNA damage by streptonigrin

Arsenic Induces Peroxynitrite Generation and Cyclooxygenase-2 Protein Expression in Aortic Endothelial Cells: Possible Role in Atherosclerosis

Novel quinolinequinone antitumor agents: Structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1)

Transdermal delivery of theophylline from alcohol vehicles

Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones

Indolequinone antitumor agents: Relationship between quinone structure and rate of metabolism by recombinant human NQO1

Transdermal delivery of 5-fluorouracil (5-FU) by 1-alkylcarbonyl-5-FU prodrugs

Arsenic Exposure in Pregnant Mice Disrupts Placental Vasculogenesis and Causes Spontaneous Abortion

The estimation of relative water solubility for prodrugs that are unstable in water

Topical delivery of 5-fluorouracil (5-FU) by 1,3-bisalkylcarbonyl-5-FU prodrugs

Noncovalent binding of a mitomycin C metabolite, 2,7-diaminomitosene, to duplex DNA

Stability of sumatriptan succinate in extemporaneously prepared oral liquids

1,3-Bisalkylcarbonyl- and 3-Alkylcarbonyl-5-fluorouracil Prodrugs: Syntheses, Thermal, and Hydrolytic Stability

1-Alkylcarbonyl-5-fluorouracil Prodrugs: Synthesis, Thermal and Hydrolytic Stability

Structure of 3-acetyl-5-fluorouracil (5-FU) : implication for its rearrangements during hydrolysis and upon heating

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