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Implications and concepts of polyamine-nucleic acid interactions

Journal of cellular biochemistry, 1991-05, Vol.46 (1), p.37-47

1991

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Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes

Biochemical journal, 1990-07, Vol.269 (2), p.329-334

1990

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Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells

Biochemical journal, 1992-03, Vol.282 (3), p.723-727

1992

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The interaction of spermine and pentamines with DNA

Biochemical journal, 1987-05, Vol.244 (1), p.243-246

1987

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Differential effects of spermine and its analogues on the structures of polynucleotides complexed with ethidium bromide

Biochemical journal, 1993-04, Vol.291 (1), p.269-274

1993

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The mechanism of polyamine analog-induced enhancement of cisplatin cytotoxicity in the U-251 MG human malignant glioma cell line

Cancer chemotherapy and pharmacology, 1998, Vol.41 (5), p.398-402

1998

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A new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus

Biochemical journal, 1995-11, Vol.312 ( Pt 1) (1), p.83-90

1995

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Polyamine analog bis(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) enhances simian virus 40 late gene expression

Cancer chemotherapy and pharmacology, 1999, Vol.43 (4), p.336-340

1999

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Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs

Molecular pharmacology, 1992-08, Vol.42 (2), p.302-306

1992

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Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts

Cancer research (Chicago, Ill.), 1994-09, Vol.54 (17), p.4698-4702

1994

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Design and testing of novel cytotoxic polyamine analogues

Cancer research (Chicago, Ill.), 1994-12, Vol.54 (23), p.6210-6214

1994

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α-difluoromethylornithine alters calcium signaling in platelet-derived growth factor-stimulated A172 brain tumor cells in culture

Cancer research (Chicago, Ill.), 1992-12, Vol.52 (24), p.6782-6789

1992

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Treatment with a polyamine analog alters DNA-matrix association in HeLa cell nuclei: A nucleoid halo assay

Biochemistry (Easton), 1993-04, Vol.32 (15), p.4073-4076

1993

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Cis-Unsaturated Analogues of 3,8,13,18,23-Pentaazapentacosane (BE-4-4-4-4): Synthesis and Growth Inhibitory Effects on Human Prostate Cancer Cell Lines

Journal of medicinal chemistry, 2001-02, Vol.44 (3), p.404-417

2001

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The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effects on cytotoxicity of cis-diaminedichloroplatinum (II) (CDDP) in human brain tumor cell lines

Anticancer research, 1996-01, Vol.16 (1), p.39

1996

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Slowing proliferation in head and neck tumors: In vitro growth inhibitory effects of the polyamine analog BE-4-4-4-4 in human squamous cell carcinomas

International journal of radiation oncology, biology, physics, 1995-06, Vol.32 (3), p.687-694

1995

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A stopped-flow H-D exchange kinetic study of spermine-polynucleotide interactions

Nucleic acids research, 1987-07, Vol.15 (14), p.5873-5886

1987

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Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines

Cancer research (Chicago, Ill.), 1993-09, Vol.53 (17), p.3948-3955

1993

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Effects of the polyamine analogs BE-3-7-3, 3-8-3, and BE-3-8-3 on human brain tumor cell growth and survival

Anticancer research, 1993-09, Vol.13 (5A), p.1525

1993

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Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells

Cellular and molecular biology (Noisy-le-Grand, France), 1994-11, Vol.40 (7), p.975

1994

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Conformationally restricted analogues of 1N, 12N-bisethylspermine : Synthesis and growth inhibitory effects on human tumor cell lines

Journal of medicinal chemistry, 1998-11, Vol.41 (24), p.4723-4732

1998

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CYTOTOXICITY OF POLYAMINE ANALOGS IS DIRECTLY RELATED TO THEIR DNA AFFINITY AS DETERMINED BY POLYACRYLAMIDE GEL COELECTROPHORESIS (PACE) METHOD

Journal of biological systems, 2004-12, Vol.12 (4), p.387-397

2004

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The structure of polyamine analogues determines haemoglobin production and cytotoxicity in murine erythroleukaemia cells

Biochemical journal, 1995-08, Vol.309 ( Pt 3) (3), p.787-791

1995

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Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines

Cancer chemotherapy and pharmacology, 1995, Vol.36 (5), p.411-417

1995

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Correlation between the effects of polyamine analogues on DNA conformation and cell growth

Cancer research (Chicago, Ill.), 1989-10, Vol.49 (20), p.5591-5597

1989

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Implications and concepts of polyamine-nucleic acid interactions

Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes

Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells

The interaction of spermine and pentamines with DNA

Differential effects of spermine and its analogues on the structures of polynucleotides complexed with ethidium bromide

The mechanism of polyamine analog-induced enhancement of cisplatin cytotoxicity in the U-251 MG human malignant glioma cell line

A new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus

Polyamine analog bis(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) enhances simian virus 40 late gene expression

Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs

Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts

Design and testing of novel cytotoxic polyamine analogues

α-difluoromethylornithine alters calcium signaling in platelet-derived growth factor-stimulated A172 brain tumor cells in culture

Treatment with a polyamine analog alters DNA-matrix association in HeLa cell nuclei: A nucleoid halo assay

Cis-Unsaturated Analogues of 3,8,13,18,23-Pentaazapentacosane (BE-4-4-4-4): Synthesis and Growth Inhibitory Effects on Human Prostate Cancer Cell Lines

The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effects on cytotoxicity of cis-diaminedichloroplatinum (II) (CDDP) in human brain tumor cell lines

Slowing proliferation in head and neck tumors: In vitro growth inhibitory effects of the polyamine analog BE-4-4-4-4 in human squamous cell carcinomas

A stopped-flow H-D exchange kinetic study of spermine-polynucleotide interactions

Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines

Effects of the polyamine analogs BE-3-7-3, 3-8-3, and BE-3-8-3 on human brain tumor cell growth and survival

Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells

Conformationally restricted analogues of 1N, 12N-bisethylspermine : Synthesis and growth inhibitory effects on human tumor cell lines

CYTOTOXICITY OF POLYAMINE ANALOGS IS DIRECTLY RELATED TO THEIR DNA AFFINITY AS DETERMINED BY POLYACRYLAMIDE GEL COELECTROPHORESIS (PACE) METHOD

The structure of polyamine analogues determines haemoglobin production and cytotoxicity in murine erythroleukaemia cells

Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines

Correlation between the effects of polyamine analogues on DNA conformation and cell growth

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