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p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16), p.3251-3264

2020

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Fructose 2,6-Bisphosphate in Cancer Cell Metabolism

Frontiers in oncology, 2018-09, Vol.8, p.331-331

2018

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CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver Fibrosis

Gastroenterology (New York, N.Y. 1943), 2020-07, Vol.159 (1), p.273-288

2020

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Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice

Diabetes (New York, N.Y.), 2015-09, Vol.64 (9), p.3093-3103

2015

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TGF‐β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

The FEBS journal, 2017-10, Vol.284 (20), p.3437-3454

2017

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Amino Acids Activate Mammalian Target of Rapamycin Complex 2 (mTORC2) via PI3K/Akt Signaling

The Journal of biological chemistry, 2011-02, Vol.286 (8), p.6128-6142

2011

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HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

Arteriosclerosis, thrombosis, and vascular biology, 2015-06, Vol.35 (6), p.1463

2015

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The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling

Scientific reports, 2020-01, Vol.10 (1), p.824-824, Article 824

2020

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The potential utility of PFKFB3 as a therapeutic target

Expert opinion on therapeutic targets, 2018-08, Vol.22 (8), p.659-674

2018

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Editorial: Cancer Ecosystems

Frontiers in oncology, 2019-08, Vol.9, p.718-718

2019

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The E3 Ubiquitin Protein Ligase HERC2 Modulates the Activity of Tumor Protein p53 by Regulating Its Oligomerization

The Journal of biological chemistry, 2014-05, Vol.289 (21), p.14782-14795

2014

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Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2

Molecular oncology, 2020-01, Vol.14 (1), p.69-86

2020

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The Expression of TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Can Be Controlled by the Antioxidant Orchestrator NRF2 in Human Carcinoma Cells

International journal of molecular sciences, 2022-02, Vol.23 (3), p.1905

2022

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Akt-dependent Activation of the Heart 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB2) Isoenzyme by Amino Acids

The Journal of biological chemistry, 2013-04, Vol.288 (15), p.10640-10651

2013

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PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

Biochemical journal, 2013-06, Vol.452 (3), p.531-543

2013

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TP53 induced glycolysis and apoptosis regulator (TIGAR) knockdown results in radiosensitization of glioma cells

Radiotherapy and oncology, 2011-10, Vol.101 (1), p.132-139

2011

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TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Is Upregulated in Lymphocytes Stimulated with Concanavalin A

International journal of molecular sciences, 2021-07, Vol.22 (14), p.7436

2021

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Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice

Diabetes (New York, N.Y.), 2008-08, Vol.57 (8), p.2199-2210

2008

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The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

Oncotarget, 2018-07, Vol.9 (59), p.31531-31548

2018

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Neuregulin improves response to glucose tolerance test in control and diabetic rats

American journal of physiology: endocrinology and metabolism, 2016-03, Vol.310 (6), p.E440-E451

2016

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The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

Oncotarget, 2016-08, Vol.7 (35), p.56083-56106

2016

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Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways

Journal of bone and mineral research, 2011-04, Vol.26 (4), p.718-729

2011

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Cooperation of Adenosine with Macrophage Toll-4 Receptor Agonists Leads to Increased Glycolytic Flux through the Enhanced Expression of PFKFB3 Gene

The Journal of biological chemistry, 2011-06, Vol.286 (22), p.19247-19258

2011

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Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide

PloS one, 2013-09, Vol.8 (9), p.e75523

2013

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6-Phosphofructo-2-kinase (pfkfb3) Gene Promoter Contains Hypoxia-inducible Factor-1 Binding Sites Necessary for Transactivation in Response to Hypoxia

The Journal of biological chemistry, 2004-12, Vol.279 (51), p.53562-53570

2004

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p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis

Fructose 2,6-Bisphosphate in Cancer Cell Metabolism

CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver Fibrosis

Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice

TGF‐β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

Amino Acids Activate Mammalian Target of Rapamycin Complex 2 (mTORC2) via PI3K/Akt Signaling

HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling

The potential utility of PFKFB3 as a therapeutic target

Editorial: Cancer Ecosystems

The E3 Ubiquitin Protein Ligase HERC2 Modulates the Activity of Tumor Protein p53 by Regulating Its Oligomerization

Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2

The Expression of TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Can Be Controlled by the Antioxidant Orchestrator NRF2 in Human Carcinoma Cells

Akt-dependent Activation of the Heart 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB2) Isoenzyme by Amino Acids

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

TP53 induced glycolysis and apoptosis regulator (TIGAR) knockdown results in radiosensitization of glioma cells

TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Is Upregulated in Lymphocytes Stimulated with Concanavalin A

Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

Neuregulin improves response to glucose tolerance test in control and diabetic rats

The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways

Cooperation of Adenosine with Macrophage Toll-4 Receptor Agonists Leads to Increased Glycolytic Flux through the Enhanced Expression of PFKFB3 Gene

Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide

6-Phosphofructo-2-kinase (pfkfb3) Gene Promoter Contains Hypoxia-inducible Factor-1 Binding Sites Necessary for Transactivation in Response to Hypoxia

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