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Low doses of sarizotan reduce dyskinesias and maintain antiparkinsonian efficacy of l -Dopa in parkinsonian monkeys

Parkinsonism & related disorders, 2009-07, Vol.15 (6), p.445-452

2009

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Effects of sarizotan on the corticostriatal glutamate pathways

Synapse (New York, N.Y.), 2005-12, Vol.58 (3), p.193-199

2005

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Selective serotonin 5-HT2A receptor antagonist EMD 281014 improves delayed matching performance in young and aged rhesus monkeys

Psychopharmacologia, 2005-06, Vol.179 (4), p.725-732

2005

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The highly selective 5-hydroxytryptamine (5-HT)2A receptor antagonist, EMD 281014, significantly increases swimming and decreases immobility in male congenital learned helpless rats in the forced swim test

Synapse (New York, N.Y.), 2004-04, Vol.52 (1), p.73-75

2004

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Electrophysiological evidence for rapid 5-HT1A autoreceptor inhibition by vilazodone, a 5-HT1A receptor partial agonist and 5-HT reuptake inhibitor

European journal of pharmacology, 2013-08, Vol.714 (1-3), p.359-365

2013

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Synthesis and Structure−Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors

Journal of medicinal chemistry, 2004-09, Vol.47 (19), p.4684-4692

2004

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Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodone

European journal of pharmacology, 2005-03, Vol.510 (1-2), p.49-57

2005

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The novel antidyskinetic drug sarizotan elicits different functional responses at human D2-like dopamine receptors

Neuropharmacology, 2006-09, Vol.51 (4), p.873-884

2006

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Prophylactic and therapeutic effects of acute systemic injections of EMD 281014, a selective serotonin 2A receptor antagonist on anxiety induced by predator stress in rats

European journal of pharmacology, 2004-11, Vol.504 (1), p.79-96

2004

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New (Sulfonyloxy)piperazinyldibenzazepines as Potential Atypical Antipsychotics: Chemistry and Pharmacological Evaluation

Journal of medicinal chemistry, 1999-06, Vol.42 (12), p.2235-2244

1999

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Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination of indole-butyl-amine and chromenonyl-piperazine structural elements in a single molecular entity

Bioorganic & medicinal chemistry, 2004-09, Vol.12 (18), p.4843-4852

2004

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Subcutaneous, intrathecal and periaqueductal grey administration of asimadoline and ICI-204448 reduces tactile allodynia in the rat

European journal of pharmacology, 2007-11, Vol.573 (1), p.75-83

2007

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The effect of chronic administration of sarizotan, 5-HT1A agonist/D3/D4 ligand, on haloperidol-induced repetitive jaw movements in rat model of tardive dyskinesia

Progress in neuro-psychopharmacology & biological psychiatry, 2006-03, Vol.30 (2), p.273-279

2006

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EMD 281014, a new selective serotonin 5-HT2A receptor antagonist

European journal of pharmacology, 2003-07, Vol.473 (2-3), p.229-230

2003

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Effects of systemic injections of Vilazodone, a selective serotonin reuptake inhibitor and serotonin 1A receptor agonist, on anxiety induced by predator stress in rats

European journal of pharmacology, 2004-11, Vol.504 (1-2), p.65-77

2004

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Effect of vilazodone on 5-HT efflux and re-uptake in the guinea-pig dorsal raphe nucleus

European journal of pharmacology, 2005-07, Vol.517 (1), p.59-63

2005

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Indolebutylamines as Selective 5-HT1A Agonists

Journal of medicinal chemistry, 2004-09, Vol.47 (19), p.4677-4683

2004

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The κ-opioid receptor agonist asimadoline inhibits epithelial transport in mouse trachea and colon

European journal of pharmacology, 2004-10, Vol.503 (1), p.185-190

2004

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Systemic EMD 68843 injections reduce anxiety in the shock-probe, but not the plus-maze test

European journal of pharmacology, 2001-03, Vol.414 (2), p.245-248

2001

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Effects of systemic injections of Vilazodone, a selective serotonin reuptake inhibitor and serotonin 1 A receptor agonist, on anxiety induced by predator stress in rats

European journal of pharmacology, 2004-11, Vol.504 (1), p.65-77

2004

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Synthesis and in Vitro and in Vivo Functional Studies of Ortho-Substituted Phenylpiperazine and N-Substituted 4-N-(o-Methoxyphenyl)aminopiperidine Analogues of WAY100635

Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.432-439

2000

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Bioisosterism of Fluorine and Cyano as Indole Substituents. Theoretical, in vitro and in vivo Examination

Chimia, 2004-03, Vol.58 (3), p.143

2004

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Sar of novel biarylmethylamine dopamine D4 receptor ligands

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (15), p.2033-2038

1998

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Role of dopamine D3 and serotonin 5-HT1A receptors in l-DOPA-induced dyskinesias and effects of sarizotan in the 6-hydroxydopamine-lesioned rat model of Parkinson’s disease

Journal of Neural Transmission, 2011-12, Vol.118 (12), p.1733-1742

2011

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Role of dopamine D sub(3) and serotonin 5-HT sub(1A) receptors in l-DOPA-induced dyskinesias and effects of sarizotan in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease

Journal of Neural Transmission, 2011-12, Vol.118 (12), p.1733-1742

2011

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Low doses of sarizotan reduce dyskinesias and maintain antiparkinsonian efficacy of l -Dopa in parkinsonian monkeys

Effects of sarizotan on the corticostriatal glutamate pathways

Selective serotonin 5-HT2A receptor antagonist EMD 281014 improves delayed matching performance in young and aged rhesus monkeys

The highly selective 5-hydroxytryptamine (5-HT)2A receptor antagonist, EMD 281014, significantly increases swimming and decreases immobility in male congenital learned helpless rats in the forced swim test

Electrophysiological evidence for rapid 5-HT1A autoreceptor inhibition by vilazodone, a 5-HT1A receptor partial agonist and 5-HT reuptake inhibitor

Synthesis and Structure−Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors

Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodone

The novel antidyskinetic drug sarizotan elicits different functional responses at human D2-like dopamine receptors

Prophylactic and therapeutic effects of acute systemic injections of EMD 281014, a selective serotonin 2A receptor antagonist on anxiety induced by predator stress in rats

New (Sulfonyloxy)piperazinyldibenzazepines as Potential Atypical Antipsychotics: Chemistry and Pharmacological Evaluation

Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination of indole-butyl-amine and chromenonyl-piperazine structural elements in a single molecular entity

Subcutaneous, intrathecal and periaqueductal grey administration of asimadoline and ICI-204448 reduces tactile allodynia in the rat

The effect of chronic administration of sarizotan, 5-HT1A agonist/D3/D4 ligand, on haloperidol-induced repetitive jaw movements in rat model of tardive dyskinesia

EMD 281014, a new selective serotonin 5-HT2A receptor antagonist

Effects of systemic injections of Vilazodone, a selective serotonin reuptake inhibitor and serotonin 1A receptor agonist, on anxiety induced by predator stress in rats

Effect of vilazodone on 5-HT efflux and re-uptake in the guinea-pig dorsal raphe nucleus

Indolebutylamines as Selective 5-HT1A Agonists

The κ-opioid receptor agonist asimadoline inhibits epithelial transport in mouse trachea and colon

Systemic EMD 68843 injections reduce anxiety in the shock-probe, but not the plus-maze test

Effects of systemic injections of Vilazodone, a selective serotonin reuptake inhibitor and serotonin 1 A receptor agonist, on anxiety induced by predator stress in rats

Synthesis and in Vitro and in Vivo Functional Studies of Ortho-Substituted Phenylpiperazine and N-Substituted 4-N-(o-Methoxyphenyl)aminopiperidine Analogues of WAY100635

Bioisosterism of Fluorine and Cyano as Indole Substituents. Theoretical, in vitro and in vivo Examination

Sar of novel biarylmethylamine dopamine D4 receptor ligands

Role of dopamine D3 and serotonin 5-HT1A receptors in l-DOPA-induced dyskinesias and effects of sarizotan in the 6-hydroxydopamine-lesioned rat model of Parkinson’s disease

Role of dopamine D sub(3) and serotonin 5-HT sub(1A) receptors in l-DOPA-induced dyskinesias and effects of sarizotan in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease

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