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The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

Drug metabolism reviews, 2008-01, Vol.40 (4), p.553-624

2008

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Role of Aldose Reductase in the Metabolism and Detoxification of Carnosine-Acrolein Conjugates

The Journal of biological chemistry, 2013-09, Vol.288 (39), p.28163-28179

2013

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Lipid Peroxidation Product 4-Hydroxy-trans-2-nonenal Causes Endothelial Activation by Inducing Endoplasmic Reticulum Stress

The Journal of biological chemistry, 2012-03, Vol.287 (14), p.11398-11409

2012

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Reductive Metabolism of AGE Precursors: A Metabolic Route for Preventing AGE Accumulation in Cardiovascular Tissue

Diabetes (New York, N.Y.), 2009-11, Vol.58 (11), p.2486-2497

2009

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Detoxification of aldehydes by histidine-containing dipeptides: From chemistry to clinical implications

Chemico-biological interactions, 2013-02, Vol.202 (1-3), p.288-297

2013

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Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Biochemical journal, 2007-07, Vol.405 (1), p.95-105

2007

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Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase

PloS one, 2015-07, Vol.10 (7), p.e0134506

2015

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Aldose Reductase Protects Against Early Atherosclerotic Lesion Formation in Apolipoprotein E–Null Mice

Circulation research, 2009-10, Vol.105 (8), p.793-802

2009

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Characterization of AKR1B16, a novel mouse aldo-keto reductase

Chemico-biological interactions, 2017-10, Vol.276, p.182-193

2017

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Reductive metabolism increases the proinflammatory activity of aldehyde phospholipids

Journal of lipid research, 2011-12, Vol.52 (12), p.2209-2225

2011

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Functional expression of novel human and murine AKR1B genes

Chemico-biological interactions, 2011-05, Vol.191 (1), p.177-184

2011

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Regulation of Ion Channels by Pyridine Nucleotides

Circulation research, 2013-02, Vol.112 (4), p.721-741

2013

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Dietary carnosine prevents early atherosclerotic lesion formation in apolipoprotein E-null mice

Arteriosclerosis, thrombosis, and vascular biology, 2013-06, Vol.33 (6), p.1162-1170

2013

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Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)

Chemico-biological interactions, 2011-05, Vol.191 (1), p.255-260

2011

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Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates

The Journal of biological chemistry, 2015-03, Vol.290 (10), p.6531-6545

2015

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Scaffold Attachment Factor B1 Functions in Development, Growth, and Reproduction

Molecular and Cellular Biology, 2005-04, Vol.25 (8), p.2995-3006

2005

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Catalytic Mechanism and Substrate Specificity of the β-Subunit of the Voltage-Gated Potassium Channel

Biochemistry (Easton), 2008-08, Vol.47 (34), p.8840-8854

2008

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Developmental expression and function of aldehyde reductase in proximal tubules of the kidney

American journal of physiology. Renal physiology, 2005-07, Vol.289 (1), p.F200-F207

2005

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Acrolein consumption induces systemic dyslipidemia and lipoprotein modification

Toxicology and applied pharmacology, 2010-02, Vol.243 (1), p.1-12

2010

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Interactions between the C-terminus of Kv1.5 and Kvβ regulate pyridine nucleotide-dependent changes in channel gating

Pflügers Archiv, 2012-06, Vol.463 (6), p.799-818

2012

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Postischemic Deactivation of Cardiac Aldose Reductase: ROLE OF GLUTATHIONE S-TRANSFERASE P AND GLUTAREDOXIN IN REGENERATION OF REDUCED THIOLS FROM SULFENIC ACIDS

The Journal of biological chemistry, 2010-08, Vol.285 (34), p.26135-26148

2010

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Alternative splicing in the aldo–keto reductase superfamily: Implications for protein nomenclature

Chemico-biological interactions, 2013-02, Vol.202 (1-3), p.153-158

2013

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NADPH binding to β-subunit regulates inactivation of voltage-gated K + channels

Biochemical and biophysical research communications, 2007-07, Vol.359 (2), p.269-276

2007

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Metabolism of trans, trans-muconaldehyde, a cytotoxic metabolite of benzene, in mouse liver by alcohol dehydrogenase Adh1 and aldehyde reductase AKR1A4

Toxicology and applied pharmacology, 2006-01, Vol.210 (1), p.163-170

2006

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Kinetics of nucleotide binding to the β-subunit (AKR6A2) of the voltage-gated potassium (Kv) channel

Chemico-biological interactions, 2009-03, Vol.178 (1), p.165-170

2009

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The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

Role of Aldose Reductase in the Metabolism and Detoxification of Carnosine-Acrolein Conjugates

Lipid Peroxidation Product 4-Hydroxy-trans-2-nonenal Causes Endothelial Activation by Inducing Endoplasmic Reticulum Stress

Reductive Metabolism of AGE Precursors: A Metabolic Route for Preventing AGE Accumulation in Cardiovascular Tissue

Detoxification of aldehydes by histidine-containing dipeptides: From chemistry to clinical implications

Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase

Aldose Reductase Protects Against Early Atherosclerotic Lesion Formation in Apolipoprotein E–Null Mice

Characterization of AKR1B16, a novel mouse aldo-keto reductase

Reductive metabolism increases the proinflammatory activity of aldehyde phospholipids

Functional expression of novel human and murine AKR1B genes

Regulation of Ion Channels by Pyridine Nucleotides

Dietary carnosine prevents early atherosclerotic lesion formation in apolipoprotein E-null mice

Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)

Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates

Scaffold Attachment Factor B1 Functions in Development, Growth, and Reproduction

Catalytic Mechanism and Substrate Specificity of the β-Subunit of the Voltage-Gated Potassium Channel

Developmental expression and function of aldehyde reductase in proximal tubules of the kidney

Acrolein consumption induces systemic dyslipidemia and lipoprotein modification

Interactions between the C-terminus of Kv1.5 and Kvβ regulate pyridine nucleotide-dependent changes in channel gating

Postischemic Deactivation of Cardiac Aldose Reductase: ROLE OF GLUTATHIONE S-TRANSFERASE P AND GLUTAREDOXIN IN REGENERATION OF REDUCED THIOLS FROM SULFENIC ACIDS

Alternative splicing in the aldo–keto reductase superfamily: Implications for protein nomenclature

NADPH binding to β-subunit regulates inactivation of voltage-gated K + channels

Metabolism of trans, trans-muconaldehyde, a cytotoxic metabolite of benzene, in mouse liver by alcohol dehydrogenase Adh1 and aldehyde reductase AKR1A4

Kinetics of nucleotide binding to the β-subunit (AKR6A2) of the voltage-gated potassium (Kv) channel

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