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The desensitization pathway of GABAA receptors, one subunit at a time

Nature communications, 2020-10, Vol.11 (1), p.5369-5369, Article 5369

2020

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Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors

Cellular and molecular life sciences : CMLS, 2021-02, Vol.78 (3), p.1051-1064

2021

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An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies

Nature communications, 2023-09, Vol.14 (1), p.5964-5964, Article 5964

2023

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Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling

Science signaling, 2019-05, Vol.12 (580)

2019

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GarA is an essential regulator of metabolism in Mycobacterium tuberculosis

Molecular microbiology, 2013-10, Vol.90 (2), p.356-366

2013

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Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

Molecular microbiology, 2008-11, Vol.70 (3), p.762-774

2008

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A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG

mBio, 2021-10, Vol.12 (5), p.e0171721-e0171721

2021

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The Ser/Thr Protein Kinase PknB Is Essential for Sustaining Mycobacterial Growth

Journal of Bacteriology, 2006-11, Vol.188 (22), p.7778-7784

2006

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The Virulence-associated Two-component PhoP-PhoR System Controls the Biosynthesis of Polyketide-derived Lipids in Mycobacterium tuberculosis

The Journal of biological chemistry, 2006-01, Vol.281 (3), p.1313-1316

2006

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The desensitization pathway of GABA A receptors, one subunit at a time

Nature communications, 2020-10, Vol.11 (1), p.5369

2020

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A Point Mutation in the Two-Component Regulator PhoP-PhoR Accounts for the Absence of Polyketide-Derived Acyltrehaloses but Not That of Phthiocerol Dimycocerosates in Mycobacterium tuberculosis H37Ra

Journal of Bacteriology, 2008-02, Vol.190 (4), p.1329-1334

2008

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Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis

FEBS letters, 2012-06, Vol.586 (11), p.1606-1611

2012

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Pentameric channel receptors A7/A3B4 and lipids: Interaction studies

Biophysical journal, 2024-02, Vol.123 (3), p.395a-395a

2024

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p-Hydroxybenzoic Acid Synthesis in Mycobacterium tuberculosis

The Journal of biological chemistry, 2005-12, Vol.280 (49), p.40699-40706

2005

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Genetic Basis for the Biosynthesis of Methylglucose Lipopolysaccharides in Mycobacterium tuberculosis

The Journal of biological chemistry, 2007-09, Vol.282 (37), p.27270-27276

2007

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Structure-based Virtual Screening to Get New Scaffold Inhibitors of the Ser/Thr Protein Kinase PknB from Mycobacterium tuberculosis

Letters in drug design & discovery, 2016-12, Vol.13 (10), p.1012-1018

2016

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Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics

Chemistry : a European journal, 2008-09, Vol.14 (28), p.8521-8529

2008

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Isoxyl Activation Is Required for Bacteriostatic Activity against Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3824-3829

2007

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Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor

Cellular and molecular life sciences : CMLS, 2023-06, Vol.80 (6), p.164-164, Article 164

2023

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A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)

Biochemical journal, 2014-02, Vol.457 (3), p.425-434

2014

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The virulence-associated twocomponent PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis

The Journal of biological chemistry, 2006-01, Vol.281 (3), p.1313-1316

2006

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Secondary structure reshuffling modulates glycosyltransferase function at the membrane

Nature chemical biology, 2015-01, Vol.11 (1), p.16-18

2015

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The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation

Proteins, structure, function, and bioinformatics, 2015-05, Vol.83 (5), p.982-988

2015

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Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis

Structure (London), 2015-06, Vol.23 (6), p.1039-1048

2015

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The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase‐like conformation

The FEBS journal, 2017-02, Vol.284 (4), p.602-614

2017

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The desensitization pathway of GABAA receptors, one subunit at a time

Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors

An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies

Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling

GarA is an essential regulator of metabolism in Mycobacterium tuberculosis

Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG

The Ser/Thr Protein Kinase PknB Is Essential for Sustaining Mycobacterial Growth

The Virulence-associated Two-component PhoP-PhoR System Controls the Biosynthesis of Polyketide-derived Lipids in Mycobacterium tuberculosis

The desensitization pathway of GABA A receptors, one subunit at a time

A Point Mutation in the Two-Component Regulator PhoP-PhoR Accounts for the Absence of Polyketide-Derived Acyltrehaloses but Not That of Phthiocerol Dimycocerosates in Mycobacterium tuberculosis H37Ra

Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis

Pentameric channel receptors A7/A3B4 and lipids: Interaction studies

p-Hydroxybenzoic Acid Synthesis in Mycobacterium tuberculosis

Genetic Basis for the Biosynthesis of Methylglucose Lipopolysaccharides in Mycobacterium tuberculosis

Structure-based Virtual Screening to Get New Scaffold Inhibitors of the Ser/Thr Protein Kinase PknB from Mycobacterium tuberculosis

Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics

Isoxyl Activation Is Required for Bacteriostatic Activity against Mycobacterium tuberculosis

Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor

A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)

The virulence-associated twocomponent PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis

Secondary structure reshuffling modulates glycosyltransferase function at the membrane

The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation

Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis

The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase‐like conformation

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