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Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy

Nature reviews. Microbiology, 2007-08, Vol.5 (8), p.583-597

Balzarini, Jan

2007

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The ProTide Prodrug Technology: From the Concept to the Clinic

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2211-2226

2018

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The dual role of thymidine phosphorylase in cancer development and chemotherapy

Medicinal research reviews, 2009-11, Vol.29 (6), p.903-953

2009

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Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission

PloS one, 2015-06, Vol.10 (6), p.e0130621

2015

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Carbohydrate-Binding Agents: A Potential Future Cornerstone for the Chemotherapy of Enveloped Viruses?

Antiviral chemistry & chemotherapy, 2007-02, Vol.18 (1), p.1-11

Balzarini, Jan

2007

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Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals

Nature communications, 2015-10, Vol.6 (1), p.8716-8716, Article 8716

2015

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Nucleoside-catabolizing Enzymes in Mycoplasma-infected Tumor Cell Cultures Compromise the Cytostatic Activity of the Anticancer Drug Gemcitabine

The Journal of biological chemistry, 2014-05, Vol.289 (19), p.13054-13065

2014

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Microbicide drug candidates to prevent HIV infection

The Lancet (British edition), 2007-03, Vol.369 (9563), p.787-797

2007

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Ribavirin Inhibits In Vitro Hepatitis E Virus Replication through Depletion of Cellular GTP Pools and Is Moderately Synergistic with Alpha Interferon

Antimicrobial Agents and Chemotherapy, 2014-01, Vol.58 (1), p.267-273

2014

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Vaginal microbiota and its role in HIV transmission and infection

FEMS microbiology reviews, 2013-09, Vol.37 (5), p.762-792

2013

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Application of ProTide Technology to Gemcitabine: A Successful Approach to Overcome the Key Cancer Resistance Mechanisms Leads to a New Agent (NUC-1031) in Clinical Development

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1531-1542

2014

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Synthesis and antiviral activity of new pyrazole and thiazole derivatives

European journal of medicinal chemistry, 2009-09, Vol.44 (9), p.3746-3753

2009

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The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications

PloS one, 2013-05, Vol.8 (5), p.e64010-e64010

2013

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Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives

European journal of medicinal chemistry, 2009-06, Vol.44 (6), p.2347-2353

2009

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The Predominant Mechanism by Which Ribavirin Exerts Its Antiviral Activity In Vitro against Flaviviruses and Paramyxoviruses Is Mediated by Inhibition of IMP Dehydrogenase

Journal of Virology, 2005-02, Vol.79 (3), p.1943-1947

2005

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Photosensitizers mediated photodynamic inactivation against virus particles

Mini reviews in medicinal chemistry, 2015-01, Vol.15 (6), p.503-521

2015

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Skin Damages-Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System

Molecules (Basel, Switzerland), 2020-09, Vol.25 (18), p.4324

2020

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Lectin-Like Molecules of Lactobacillus rhamnosus GG Inhibit Pathogenic Escherichia coli and Salmonella Biofilm Formation

PloS one, 2016-08, Vol.11 (8), p.e0161337-e0161337

2016

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Enantiocontrolled Preparation of ϒ-Substituted Cyclohexenones: Synthesis and Kinase Activity Assays of Cyclopropyl-Fused Cyclohexane Nucleosides

International journal of molecular sciences, 2022-09, Vol.23 (17), p.9704

2022

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Targeting the glycans of the HIV envelope as a therapeutic tool

Retrovirology, 2011-10, Vol.8 (S2), p.O38-O38, Article O38

Balzarini, Jan

2011

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Activity and Safety of Synthetic Lectins Based on Benzoboroxole-Functionalized Polymers for Inhibition of HIV Entry

Molecular pharmaceutics, 2011-12, Vol.8 (6), p.2465-2475

2011

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Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones

Molecules (Basel, Switzerland), 2016-04, Vol.21 (5), p.579-579

2016

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Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones

European journal of medicinal chemistry, 2007-07, Vol.42 (7), p.993-1003

2007

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Conformational States of HIV‑1 Reverse Transcriptase for Nucleotide Incorporation vs PyrophosphorolysisBinding of Foscarnet

ACS chemical biology, 2016-08, Vol.11 (8), p.2158-2164

2016

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Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3- c ]pyridine Scaffold

Molecules (Basel, Switzerland), 2020-04, Vol.25 (7), p.1690

2020

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Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy

The ProTide Prodrug Technology: From the Concept to the Clinic

The dual role of thymidine phosphorylase in cancer development and chemotherapy

Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission

Carbohydrate-Binding Agents: A Potential Future Cornerstone for the Chemotherapy of Enveloped Viruses?

Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals

Nucleoside-catabolizing Enzymes in Mycoplasma-infected Tumor Cell Cultures Compromise the Cytostatic Activity of the Anticancer Drug Gemcitabine

Microbicide drug candidates to prevent HIV infection

Ribavirin Inhibits In Vitro Hepatitis E Virus Replication through Depletion of Cellular GTP Pools and Is Moderately Synergistic with Alpha Interferon

Vaginal microbiota and its role in HIV transmission and infection

Application of ProTide Technology to Gemcitabine: A Successful Approach to Overcome the Key Cancer Resistance Mechanisms Leads to a New Agent (NUC-1031) in Clinical Development

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications

Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives

The Predominant Mechanism by Which Ribavirin Exerts Its Antiviral Activity In Vitro against Flaviviruses and Paramyxoviruses Is Mediated by Inhibition of IMP Dehydrogenase

Photosensitizers mediated photodynamic inactivation against virus particles

Skin Damages-Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System

Lectin-Like Molecules of Lactobacillus rhamnosus GG Inhibit Pathogenic Escherichia coli and Salmonella Biofilm Formation

Enantiocontrolled Preparation of ϒ-Substituted Cyclohexenones: Synthesis and Kinase Activity Assays of Cyclopropyl-Fused Cyclohexane Nucleosides

Targeting the glycans of the HIV envelope as a therapeutic tool

Activity and Safety of Synthetic Lectins Based on Benzoboroxole-Functionalized Polymers for Inhibition of HIV Entry

Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones

Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones

Conformational States of HIV‑1 Reverse Transcriptase for Nucleotide Incorporation vs PyrophosphorolysisBinding of Foscarnet

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3- c ]pyridine Scaffold

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