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CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Nature communications, 2017-02, Vol.8 (1), p.14432-18, Article 14432

2017

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Monolignol export by diffusion down a polymerization-induced concentration gradient

The Plant cell, 2022-04, Vol.34 (5), p.2080-2095

2022

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Nanoscale Reaction Vessels Designed for Synthesis of Copper-Drug Complexes Suitable for Preclinical Development

PloS one, 2016-04, Vol.11 (4), p.e0153416-e0153416

2016

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Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer

PloS one, 2013-10, Vol.8 (10), p.e76503

2013

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Accumulation of liposomes in metastatic tumor sites is not necessary for anti-cancer drug efficacy

Journal of translational medicine, 2024-07, Vol.22 (1), p.621-19, Article 621

2024

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Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer

Clinical cancer research, 2014-06, Vol.20 (12), p.3159-3173

2014

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The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type

The Journal of pathology, 2017-07, Vol.242 (3), p.371-383

2017

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Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response

International journal of molecular sciences, 2018-09, Vol.19 (10), p.2922

2018

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Sulfonation, an underexploited area: from skeletal development to infectious diseases and cancer

Oncotarget, 2016-08, Vol.7 (34), p.55811-55827

2016

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Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo

PloS one, 2013-03, Vol.8 (3), p.e58491

2013

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Rictor and Integrin-Linked Kinase Interact and Regulate Akt Phosphorylation and Cancer Cell Survival

Cancer research (Chicago, Ill.), 2008-03, Vol.68 (6), p.1618-1624

2008

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Magnetic Resonance Imaging of Temperature-Sensitive Liposome Release: Drug Dose Painting and Antitumor Effects

JNCI : Journal of the National Cancer Institute, 2007-01, Vol.99 (1), p.53-63

2007

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Loss of Parkinson's susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis

Scientific reports, 2021-01, Vol.11 (1), p.2097-14, Article 2097

2021

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Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: Relating plasma circulation lifetimes to protein binding

Biochimica et biophysica acta, 2007-06, Vol.1768 (6), p.1367-1377

2007

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A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation

Cancer research (Chicago, Ill.), 2011-07, Vol.71 (13), p.4484-4493

2011

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Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats

Journal of nanobiotechnology, 2018-10, Vol.16 (1), p.77-12, Article 77

2018

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Ratiometric dosing of anticancer drug combinations: Controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice

Molecular cancer therapeutics, 2006-07, Vol.5 (7), p.1854-1863

2006

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PEG Conjugated Zein Nanoparticles for In Vivo Use

Pharmaceutics, 2022-08, Vol.14 (9), p.1831

2022

Volltextzugriff (PDF)

Induced Vascular Normalization—Can One Force Tumors to Surrender to a Better Microenvironment?

Pharmaceutics, 2023-07, Vol.15 (8), p.2022

2023

Volltextzugriff (PDF)

Development of a liposomal nanoparticle formulation of 5-Fluorouracil for parenteral administration: Formulation design, pharmacokinetics and efficacy

Journal of controlled release, 2011-03, Vol.150 (2), p.212-219

2011

Volltextzugriff (PDF)

What Drives Innovation: The Canadian Touch on Liposomal Therapeutics

Pharmaceutics, 2019-03, Vol.11 (3), p.124

2019

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Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell Lung Cancer Cells In Vitro

PloS one, 2016-03, Vol.11 (3), p.e0150675-e0150675

2016

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Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine

BMC cancer, 2011-04, Vol.11 (1), p.124-124, Article 124

2011

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Treatment of colorectal cancer using a combination of liposomal irinotecan (Irinophore C™) and 5-fluorouracil

PloS one, 2013-04, Vol.8 (4), p.e62349

2013

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A Perspective - can copper complexes be developed as a novel class of therapeutics?

Dalton transactions : an international journal of inorganic chemistry, 2017-08, Vol.46 (33), p.1758-1773

2017

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CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Monolignol export by diffusion down a polymerization-induced concentration gradient

Nanoscale Reaction Vessels Designed for Synthesis of Copper-Drug Complexes Suitable for Preclinical Development

Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer

Accumulation of liposomes in metastatic tumor sites is not necessary for anti-cancer drug efficacy

Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type

Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response

Sulfonation, an underexploited area: from skeletal development to infectious diseases and cancer

Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo

Rictor and Integrin-Linked Kinase Interact and Regulate Akt Phosphorylation and Cancer Cell Survival

Magnetic Resonance Imaging of Temperature-Sensitive Liposome Release: Drug Dose Painting and Antitumor Effects

Loss of Parkinson's susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis

Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: Relating plasma circulation lifetimes to protein binding

A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation

Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats

Ratiometric dosing of anticancer drug combinations: Controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice

PEG Conjugated Zein Nanoparticles for In Vivo Use

Induced Vascular Normalization—Can One Force Tumors to Surrender to a Better Microenvironment?

Development of a liposomal nanoparticle formulation of 5-Fluorouracil for parenteral administration: Formulation design, pharmacokinetics and efficacy

What Drives Innovation: The Canadian Touch on Liposomal Therapeutics

Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell Lung Cancer Cells In Vitro

Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine

Treatment of colorectal cancer using a combination of liposomal irinotecan (Irinophore C™) and 5-fluorouracil

A Perspective - can copper complexes be developed as a novel class of therapeutics?

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