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Immune-checkpoint inhibitors: long-term implications of toxicity

Nature reviews. Clinical oncology, 2022-04, Vol.19 (4), p.254-267

2022

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Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

Nature reviews. Clinical oncology, 2016-11, Vol.13 (11), p.674-690

2016

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Biological Consequences of MHC-II Expression by Tumor Cells in Cancer

Clinical cancer research, 2019-04, Vol.25 (8), p.2392-2402

2019

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Mechanisms of MHC-I Downregulation and Role in Immunotherapy Response

Frontiers in immunology, 2022-02, Vol.13, p.844866-844866

2022

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Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

Journal of clinical oncology, 2011-11, Vol.29 (33), p.4452-4461

2011

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Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy

Nature nanotechnology, 2019-03, Vol.14 (3), p.269-278

2019

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Corticosteroids and Cancer Immunotherapy

Clinical cancer research, 2023-07, Vol.29 (14), p.2580-2587

2023

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MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

Cell metabolism, 2017-10, Vol.26 (4), p.633-647.e7

2017

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Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes

Nature communications, 2021-11, Vol.12 (1), p.6276-6276, Article 6276

2021

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Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration

Journal of controlled release, 2021-02, Vol.330, p.1118-1129

2021

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Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

Nature communications, 2016-01, Vol.7 (1), p.10582-10582, Article 10582

2016

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A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy

The Journal of clinical investigation, 2020-05, Vol.130 (5), p.2570-2586

2020

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DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer

Nature communications, 2018-01, Vol.9 (1), p.248-11, Article 248

2018

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Neurologic toxicity associated with immune checkpoint inhibitors: a pharmacovigilance study

Journal for immunotherapy of cancer, 2019-05, Vol.7 (1), p.134-9, Article 134

2019

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PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors

Breast cancer research : BCR, 2014-08, Vol.16 (4), p.406-406, Article 406

2014

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Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma

Journal for immunotherapy of cancer, 2020-03, Vol.8 (1), p.e000282

2020

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EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer

Cancer research (Chicago, Ill.), 2016-01, Vol.76 (2), p.305-318

2016

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Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer

Scientific reports, 2018-03, Vol.8 (1), p.4899-9, Article 4899

2018

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Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (35), p.14372-14377

2013

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Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

Nature communications, 2017-09, Vol.8 (1), p.606-18, Article 606

2017

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Artificial image objects for classification of breast cancer biomarkers with transcriptome sequencing data and convolutional neural network algorithms

Breast cancer research : BCR, 2021-10, Vol.23 (1), p.96-96, Article 96

2021

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Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4737-4752

2014

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A Critical Need for Better Cancer Immunotherapy Models: Are Organotypic Tumor Spheroid Cultures the Answer?

Cancer discovery, 2018-02, Vol.8 (2), p.143-145

2018

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Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

Nature medicine, 2012-07, Vol.18 (7), p.1052-1059

2012

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In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies

Scientific reports, 2017-05, Vol.7 (1), p.1526-11, Article 1526

2017

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Immune-checkpoint inhibitors: long-term implications of toxicity

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

Biological Consequences of MHC-II Expression by Tumor Cells in Cancer

Mechanisms of MHC-I Downregulation and Role in Immunotherapy Response

Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy

Corticosteroids and Cancer Immunotherapy

MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes

Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration

Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy

DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer

Neurologic toxicity associated with immune checkpoint inhibitors: a pharmacovigilance study

PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors

Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma

EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer

Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer

Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

Artificial image objects for classification of breast cancer biomarkers with transcriptome sequencing data and convolutional neural network algorithms

Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution

A Critical Need for Better Cancer Immunotherapy Models: Are Organotypic Tumor Spheroid Cultures the Answer?

Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies

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