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Identification and Characterization of Compounds That Potentiate NT-3-Mediated Trk Receptor Activity

Molecular pharmacology, 2006-04, Vol.69 (4), p.1396-1404

2006

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Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2258-2261

2005

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Sordaricin antifungal agents

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (3), p.519-524

2003

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1609-1612

2004

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Non-camptothecin topoisomerase I active compounds as potential anticancer agents

Expert opinion on therapeutic patents, 2000-05, Vol.10 (5), p.635-666

2000

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Novel fluoro-substituted camptothecins : in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization

Cancer chemotherapy and pharmacology, 2006-07, Vol.58 (1), p.73-85

2006

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Oxime derivatives of sordaricin as potent antifungal agents

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (6), p.943-946

2002

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Sordarin Oxazepine Derivatives as Potent Antifungal Agents

Bioorganic & medicinal chemistry letters, 2002-10, Vol.12 (19), p.2757-2760

2002

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Identification of a broad-Spectrum azasordarin with improved pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (8), p.1419-1423

2003

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Core-modified sordaricin derivatives: Synthesis and antifungal activity

Bioorganic & medicinal chemistry letters, 2002-12, Vol.12 (23), p.3403-3405

2002

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β-d-glucopyranosyl]-5H,13H-benzo[b]thienyl[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.654-654

2005

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Mild deprotection of 2-(trimethylsilyl)ethyl esters

Tetrahedron letters, 2001-12, Vol.42 (49), p.8593-8595

2001

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A practical synthesis of aryl tetrafluoroethyl ethers via the improved reaction of phenols with 1,2-dibromotetrafluoroethane

Tetrahedron letters, 2007-10, Vol.48 (42), p.7516-7519

2007

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Preparation of Monofluorophenols via the Reaction of Difluorobenzene Derivatives with Potassium Trimethylsilanoate

Synlett, 2009-03, Vol.2009 (4), p.633-637

2009

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Preface

Bioorganic & medicinal chemistry, 1995-08, Vol.3 (8), p.xi

Balasubramanian, Balu N.

1995

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Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3-a]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp3 Carbon

Organic letters, 2005-03, Vol.7 (7), p.1271-1274

2005

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Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3- a ]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp 3 Carbon

Organic letters, 2005-03, Vol.7 (7), p.1271-1274

2005

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d -glucopyranosyl]-5 H ,13 H -benzo[ b ]thienyl[2,3- a ]pyrrolo[3,4- c ]carbazole-5,7(6 H )-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.654-654

2005

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d -glucopyranosyl]-5 H ,13 H -benzo[ b ]- thienyl[2,3- a ]pyrrolo[3,4- c ]carbazole- 5,7(6 H )-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1609-1612

2004

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Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-β-d-glucopyranosyl]-5H, 13H-benzo[b]-thien yl[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model

Journal of medicinal chemistry, 2004, Vol.47 (7), p.1609-1612

2004

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Chapter 15. Recent Developments in Cancer Cytotoxics

Annual Reports in Medicinal Chemistry, 1998, Vol.33, p.151-162

1998

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ChemInform Abstract: Preparation of Monofluorophenols via the Reaction of Difluorobenzene Derivatives with Potassium Trimethylsilanoate

ChemInform, 2009-07, Vol.40 (28), p.no-no

2009

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ChemInform Abstract: Oxime Derivatives of Sordaricin as Potent Antifungal Agents

ChemInform, 2002-08, Vol.33 (31), p.no-no

2002

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ChemInform Abstract: Mild Deprotection of 2-(Trimethylsilyl)ethyl Esters

ChemInform, 2002-03, Vol.33 (10), p.no-no

2002

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Identification and Characterization of Compounds That Potentiate NT-3-Mediated Trk Receptor Activity

Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11

Sordaricin antifungal agents

Non-camptothecin topoisomerase I active compounds as potential anticancer agents

Novel fluoro-substituted camptothecins : in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization

Oxime derivatives of sordaricin as potent antifungal agents

Sordarin Oxazepine Derivatives as Potent Antifungal Agents

Identification of a broad-Spectrum azasordarin with improved pharmacokinetic properties

Core-modified sordaricin derivatives: Synthesis and antifungal activity

Mild deprotection of 2-(trimethylsilyl)ethyl esters

A practical synthesis of aryl tetrafluoroethyl ethers via the improved reaction of phenols with 1,2-dibromotetrafluoroethane

Preparation of Monofluorophenols via the Reaction of Difluorobenzene Derivatives with Potassium Trimethylsilanoate

Preface

Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3-a]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp3 Carbon

Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3- a ]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp 3 Carbon

Chapter 15. Recent Developments in Cancer Cytotoxics

ChemInform Abstract: Preparation of Monofluorophenols via the Reaction of Difluorobenzene Derivatives with Potassium Trimethylsilanoate

ChemInform Abstract: Oxime Derivatives of Sordaricin as Potent Antifungal Agents

ChemInform Abstract: Mild Deprotection of 2-(Trimethylsilyl)ethyl Esters

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