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A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

Nature communications, 2020-10, Vol.11 (1), p.5214-5214, Article 5214

2020

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GS-9822, a preclinical LEDGIN candidate, displays a block-and-lock phenotype in cell culture

Antimicrobial agents and chemotherapy, 2021-04, Vol.65 (5)

2021

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Author Correction: A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

Nature communications, 2021-06, Vol.12 (1), p.3984-3984, Article 3984

2021

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Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells

PloS one, 2013-09, Vol.8 (9), p.e74163

2013

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Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

PLoS pathogens, 2015-11, Vol.11 (11), p.e1005233-e1005233

2015

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Evaluation of Broadly Neutralizing Antibody Sensitivity by Genotyping and Phenotyping for Qualifying Participants to HIV Clinical Trials

Journal of acquired immune deficiency syndromes (1999), 2021-09, Vol.88 (1), p.61

2021

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Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors

Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2905-2915

2011

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Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.51545-51553

2004

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RNase H Active Site Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Design, Biochemical Activity, and Structural Information

Journal of medicinal chemistry, 2009-10, Vol.52 (19), p.5781-5784

2009

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A Recombination Hot Spot in HIV-1 Contains Guanosine Runs That Can Form a G-quartet Structure and Promote Strand Transfer in Vitro

The Journal of biological chemistry, 2009-12, Vol.284 (49), p.33883-33893

2009

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Reduced dNTP Interaction of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Promotes Strand Transfer

The Journal of biological chemistry, 2006-10, Vol.281 (43), p.32113-32121

2006

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Insights into the Multiple Roles of Pausing in HIV-1 Reverse Transcriptase-promoted Strand Transfers

The Journal of biological chemistry, 2007-03, Vol.282 (9), p.6222-6231

2007

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Apparent Defects in Processive DNA Synthesis, Strand Transfer, and Primer Elongation of Met-184 Mutants of HIV-1 Reverse Transcriptase Derive Solely from a dNTP Utilization Defect

The Journal of biological chemistry, 2008-04, Vol.283 (14), p.9196-9205

2008

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BMF-219: A Novel Therapeutic Agent to Reestablish Functional Beta Cells and Provide Long-Term Glycemic Control

Metabolism, clinical and experimental, 2024-06, Vol.153, p.155884, Article 155884

2024

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Template Dimerization Promotes an Acceptor Invasion-Induced Transfer Mechanism during Human Immunodeficiency Virus Type 1 Minus-Strand Synthesis

Journal of Virology, 2003-04, Vol.77 (8), p.4710-4721

2003

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Steps of the Acceptor Invasion Mechanism for HIV-1 Minus Strand Strong Stop Transfer

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38368-38375

2003

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Preclinical activity of irreversible Menin inhibitor, BMF-219, in chronic lymphocytic leukemia

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.7541-7541

2022

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Role of the Reverse Transcriptase, Nucleocapsid Protein, and Template Structure in the Two-step Transfer Mechanism in Retroviral Recombination

The Journal of biological chemistry, 2003-08, Vol.278 (34), p.31536-31546

2003

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Identification of a preferred region for recombination and mutation in HIV-1 gag

Virology (New York, N.Y.), 2004-09, Vol.326 (2), p.262-279

2004

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Strand Transfer Occurs in Retroviruses by a Pause-initiated Two-step Mechanism

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.46900-46911

2002

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Adsorptive stripping potentiometry of DNA at electrochemically pretreated carbon paste electrodes

Electroanalysis (New York, N.Y.), 1996-01, Vol.8 (1), p.20-24

1996

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Unique Progressive Cleavage Mechanism of HIV Reverse Transcriptase RNase H

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (22), p.11978-11983

2000

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Acceptor RNA Cleavage Profile Supports an Invasion Mechanism for HIV-1 Minus Strand Transfer

The Journal of biological chemistry, 2005-04, Vol.280 (15), p.14443-14452

2005

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Bmf-500: An Orally Bioavailable Covalent Inhibitor of FLT3 with High Selectivity and Potent Antileukemic Activity in FLT3-Mutated AML

Blood, 2022-11, Vol.140 (Supplement 1), p.6191-6192

2022

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A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

GS-9822, a preclinical LEDGIN candidate, displays a block-and-lock phenotype in cell culture

Author Correction: A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19

Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells

Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

Evaluation of Broadly Neutralizing Antibody Sensitivity by Genotyping and Phenotyping for Qualifying Participants to HIV Clinical Trials

Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors

Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase

RNase H Active Site Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Design, Biochemical Activity, and Structural Information

A Recombination Hot Spot in HIV-1 Contains Guanosine Runs That Can Form a G-quartet Structure and Promote Strand Transfer in Vitro

Reduced dNTP Interaction of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Promotes Strand Transfer

Insights into the Multiple Roles of Pausing in HIV-1 Reverse Transcriptase-promoted Strand Transfers

Apparent Defects in Processive DNA Synthesis, Strand Transfer, and Primer Elongation of Met-184 Mutants of HIV-1 Reverse Transcriptase Derive Solely from a dNTP Utilization Defect

BMF-219: A Novel Therapeutic Agent to Reestablish Functional Beta Cells and Provide Long-Term Glycemic Control

Template Dimerization Promotes an Acceptor Invasion-Induced Transfer Mechanism during Human Immunodeficiency Virus Type 1 Minus-Strand Synthesis

Steps of the Acceptor Invasion Mechanism for HIV-1 Minus Strand Strong Stop Transfer

Preclinical activity of irreversible Menin inhibitor, BMF-219, in chronic lymphocytic leukemia

Role of the Reverse Transcriptase, Nucleocapsid Protein, and Template Structure in the Two-step Transfer Mechanism in Retroviral Recombination

Identification of a preferred region for recombination and mutation in HIV-1 gag

Strand Transfer Occurs in Retroviruses by a Pause-initiated Two-step Mechanism

Adsorptive stripping potentiometry of DNA at electrochemically pretreated carbon paste electrodes

Unique Progressive Cleavage Mechanism of HIV Reverse Transcriptase RNase H

Acceptor RNA Cleavage Profile Supports an Invasion Mechanism for HIV-1 Minus Strand Transfer

Bmf-500: An Orally Bioavailable Covalent Inhibitor of FLT3 with High Selectivity and Potent Antileukemic Activity in FLT3-Mutated AML

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