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Protein Therapeutics

1st, 2017

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Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer

PLoS genetics, 2016-04, Vol.12 (4), p.e1005895-e1005895

2016

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MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

Nature communications, 2015-05, Vol.6 (1), p.7096-7096, Article 7096

2015

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Developing innovative targeted therapies for China

Journal of translational medicine, 2012-10, Vol.10 (S2), p.A3-A3, Article A3

Jallal, Bahija

2012

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Targeting the Insulin-like Growth Factor Axis for the Development of Novel Therapeutics in Oncology

Cancer research (Chicago, Ill.), 2012, Vol.72 (1), p.3-12

2012

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In Vivo Therapeutic Success of MicroRNA‐155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage

Arthritis & rheumatology (Hoboken, N.J.), 2016-04, Vol.68 (4), p.953-964

2016

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TRAF6-Dependent Act1 Phosphorylation by the IκB Kinase-Related Kinases Suppresses Interleukin-17-Induced NF-κB Activation

Molecular and Cellular Biology, 2012-10, Vol.32 (19), p.3925-3937

2012

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Inhibition of Myogenic MicroRNAs 1, 133, and 206 by Inflammatory Cytokines Links Inflammation and Muscle Degeneration in Adult Inflammatory Myopathies

Arthritis & rheumatology (Hoboken, N.J.), 2014-04, Vol.66 (4), p.1022-1033

2014

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Type I interferon: potential therapeutic target for psoriasis?

PloS one, 2008-07, Vol.3 (7), p.e2737-e2737

2008

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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (3), p.1029-1040

2011

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MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D

Pigment cell and melanoma research, 2014-03, Vol.27 (2), p.275-286

2014

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EphB4 promotes or suppresses Ras/MEK/ERK pathway in a context-dependent manner: Implications for EphB4 as a cancer target

Cancer biology & therapy, 2012-06, Vol.13 (8), p.630-637

2012

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PAK4 mediates morphological changes through the regulation of GEF-H1

Journal of cell science, 2005-05, Vol.118 (9), p.1861-1872

2005

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Altered expression of insulin receptor isoforms in breast cancer

PloS one, 2011-10, Vol.6 (10), p.e26177-e26177

2011

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Permissive environment for B-cell maturation in myositis muscle in the absence of B-cell follicles

Muscle & nerve, 2010-10, Vol.42 (4), p.576-583

2010

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Requirement for PAK4 in the Anchorage-independent Growth of Human Cancer Cell Lines

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.550-558

2002

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The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells

Blood, 2008-08, Vol.112 (3), p.711-720

2008

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Bahija Jallal

Nature reviews. Drug discovery, 2019-03

2019

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A whole genome transcriptional analysis of the early immune response induced by live attenuated and inactivated influenza vaccines in young children

Vaccine, 2010-04, Vol.28 (16), p.2865-2876

2010

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Genomic signatures characterize leukocyte infiltration in myositis muscles

BMC medical genomics, 2012-11, Vol.5 (1), p.53-53, Article 53

2012

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Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2–positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib

Molecular cancer therapeutics, 2009-08, Vol.8 (8), p.2131-2141

2009

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The Serine/Threonine Kinase Nek6 Is Required for Cell Cycle Progression through Mitosis

The Journal of biological chemistry, 2003-12, Vol.278 (52), p.52454-52460

2003

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CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice

Clinical cancer research, 2006-08, Vol.12 (16), p.4908-4915

2006

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The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Molecular and Cellular Biology, 2003-03, Vol.23 (6), p.2068-2082

2003

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Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases

Bioorganic & medicinal chemistry, 2003-04, Vol.11 (8), p.1835-1849

2003

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Protein Therapeutics

Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

Developing innovative targeted therapies for China

Targeting the Insulin-like Growth Factor Axis for the Development of Novel Therapeutics in Oncology

In Vivo Therapeutic Success of MicroRNA‐155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage

TRAF6-Dependent Act1 Phosphorylation by the IκB Kinase-Related Kinases Suppresses Interleukin-17-Induced NF-κB Activation

Inhibition of Myogenic MicroRNAs 1, 133, and 206 by Inflammatory Cytokines Links Inflammation and Muscle Degeneration in Adult Inflammatory Myopathies

Type I interferon: potential therapeutic target for psoriasis?

Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D

EphB4 promotes or suppresses Ras/MEK/ERK pathway in a context-dependent manner: Implications for EphB4 as a cancer target

PAK4 mediates morphological changes through the regulation of GEF-H1

Altered expression of insulin receptor isoforms in breast cancer

Permissive environment for B-cell maturation in myositis muscle in the absence of B-cell follicles

Requirement for PAK4 in the Anchorage-independent Growth of Human Cancer Cell Lines

The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells

Bahija Jallal

A whole genome transcriptional analysis of the early immune response induced by live attenuated and inactivated influenza vaccines in young children

Genomic signatures characterize leukocyte infiltration in myositis muscles

Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2–positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib

The Serine/Threonine Kinase Nek6 Is Required for Cell Cycle Progression through Mitosis

CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases

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