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Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity

Scientific reports, 2018-05, Vol.8 (1), p.8078-22, Article 8078

2018

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60 Years of viral vaccines

Human vaccines & immunotherapeutics, 2022-11, Vol.18 (4), p.2017204-2017204

Wahren, Britta

2022

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Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses

Human vaccines & immunotherapeutics, 2017-12, Vol.13 (12), p.2849-2858

2017

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Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression

Molecular therapy. Nucleic acids, 2014-01, Vol.3 (1), p.e140-e140, Article e140

2014

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DNA–VLP prime–boost intra-nasal immunization induces cellular and humoral anti-HIV-1 systemic and mucosal immunity with cross-clade neutralizing activity

Vaccine, 2007-08, Vol.25 (32), p.5968-5977

2007

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Amplified antigen-specific immune responses in HIV-1 infected individuals in a double blind DNA immunization and therapy interruption trial

Vaccine, 2011-07, Vol.29 (33), p.5558-5566

2011

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The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children

Journal of Virus Eradication, 2015-07, Vol.1 (3), p.134-139

2015

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HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV

Heliyon, 2017-06, Vol.3 (6), p.e00339-e00339, Article e00339

2017

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Multi-subtype gp160 DNA immunization induces broadly neutralizing anti-HIV antibodies

Gene therapy, 2004-07, Vol.11 (14), p.1146-1154

2004

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Enhancement of epitope-specific cellular immune responses by immunization with HIV-1 peptides genetically conjugated to the B-subunit of recombinant cholera toxin

Vaccine, 2008-09, Vol.26 (40), p.5079-5082

2008

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Suppression of experimental autoimmune neuritis by ABR-215062 is associated with altered Th1/Th2 balance and inhibited migration of inflammatory cells into the peripheral nerve tissue

Neuropharmacology, 2002-04, Vol.42 (5), p.731-739

2002

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DNA Vaccines: Progress and Challenges

The Journal of immunology (1950), 2005-07, Vol.175 (2), p.633-639

2005

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Cross-clade immune responses to Gag p24 in patients infected with different HIV-1 subtypes and correlation with HLA class I and II alleles

Vaccine, 2008-09, Vol.26 (40), p.5182-5187

2008

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P19-29. Determining the optimal protocol for plasmid DNA vaccine delivery by intradermal in vivo electroporation

Retrovirology, 2009-10, Vol.6 (Suppl 3), p.P349-P349, Article P349

2009

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Enhanced cellular immunity and systemic control of SHIV infection by combined parenteral and mucosal administration of a DNA prime MVA boost vaccine regimen

Journal of general virology, 2004-08, Vol.85 (8), p.2407-2419

2004

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HIV in Europe — a growing threat

Journal of clinical virology, 2001-05, Vol.21 (2), p.171-173

Wahren, B.

2001

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The rationale behind a vaccine based on multiple HIV antigens

Microbes and infection, 2005-11, Vol.7 (14), p.1414-1423

2005

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Antibody-mediated inhibition of HIV-1 elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults

Retrovirology, 2012-09, Vol.9 (S2), p.O53-O53, Article O53

2012

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DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response

PloS one, 2018-06, Vol.13 (6), p.e0197902-e0197902

2018

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OA04-02. Strong HIV-specific CD4 and CD8 T-lymphocyte proliferation in HIV-1 DNA prime/modified vaccinia virus Ankara (MVA) heterologous boost vaccinees

Retrovirology, 2009-10, Vol.6 (Suppl 3), p.O26-O26, Article O26

2009

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Skin electroporation: effects on transgene expression, DNA persistence and local tissue environment

PloS one, 2009-09, Vol.4 (9), p.e7226-e7226

2009

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Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

Nucleic acids research, 2005-01, Vol.33 (1), p.439-447

2005

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Breadth, phenotype and functionality of Gag-specific T cell responses induced by a heterologous DNA/MVA prime-boost HIV-1 vaccine regimen

Retrovirology, 2012-09, Vol.9 (S2), p.P273-P273, Article P273

2012

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Preferential targeting of conserved Gag regions after vaccination with a heterologous DNA prime Modified Vaccinia Ankara boost HIV vaccine regime

Retrovirology, 2012-09, Vol.9 (S2), p.P330-P330, Article P330

2012

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P14-14 LB. A low dose of multigene, multiclade HIV DNA given intradermally induces strong and broad immune responses after boosting with heterologous HIV MVA

Retrovirology, 2009-10, Vol.6 (S3), p.P403-P403, Article P403

2009

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Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity

60 Years of viral vaccines

Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression

DNA–VLP prime–boost intra-nasal immunization induces cellular and humoral anti-HIV-1 systemic and mucosal immunity with cross-clade neutralizing activity

Amplified antigen-specific immune responses in HIV-1 infected individuals in a double blind DNA immunization and therapy interruption trial

The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children

HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV

Multi-subtype gp160 DNA immunization induces broadly neutralizing anti-HIV antibodies

Enhancement of epitope-specific cellular immune responses by immunization with HIV-1 peptides genetically conjugated to the B-subunit of recombinant cholera toxin

Suppression of experimental autoimmune neuritis by ABR-215062 is associated with altered Th1/Th2 balance and inhibited migration of inflammatory cells into the peripheral nerve tissue

DNA Vaccines: Progress and Challenges

Cross-clade immune responses to Gag p24 in patients infected with different HIV-1 subtypes and correlation with HLA class I and II alleles

P19-29. Determining the optimal protocol for plasmid DNA vaccine delivery by intradermal in vivo electroporation

Enhanced cellular immunity and systemic control of SHIV infection by combined parenteral and mucosal administration of a DNA prime MVA boost vaccine regimen

HIV in Europe — a growing threat

The rationale behind a vaccine based on multiple HIV antigens

Antibody-mediated inhibition of HIV-1 elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults

DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response

OA04-02. Strong HIV-specific CD4 and CD8 T-lymphocyte proliferation in HIV-1 DNA prime/modified vaccinia virus Ankara (MVA) heterologous boost vaccinees

Skin electroporation: effects on transgene expression, DNA persistence and local tissue environment

Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

Breadth, phenotype and functionality of Gag-specific T cell responses induced by a heterologous DNA/MVA prime-boost HIV-1 vaccine regimen

Preferential targeting of conserved Gag regions after vaccination with a heterologous DNA prime Modified Vaccinia Ankara boost HIV vaccine regime

P14-14 LB. A low dose of multigene, multiclade HIV DNA given intradermally induces strong and broad immune responses after boosting with heterologous HIV MVA

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