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Immune senescence: significance of the stromal microenvironment

Clinical and experimental immunology, 2017-01, Vol.187 (1), p.6-15

2017

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Identification of human-selective analogues of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

British journal of cancer, 2013-04, Vol.108 (6), p.1306-1315

2013

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Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs

British journal of cancer, 2000-02, Vol.82 (4), p.966-972

2000

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Comparative bioactivation of the novel anti‐tuberculosis agent PA‐824 in Mycobacteria and a subcellular fraction of human liver

British journal of pharmacology, 2011-01, Vol.162 (1), p.226-236

2011

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Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[d]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor

Journal of medicinal chemistry, 1999-05, Vol.42 (10), p.1803-1815

1999

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Tyrosine Kinase Inhibitors. 11. Soluble Analogues of Pyrrolo- and Pyrazoloquinazolines as Epidermal Growth Factor Receptor Inhibitors: Synthesis, Biological Evaluation, and Modeling of the Mode of Binding

Journal of medicinal chemistry, 1997-05, Vol.40 (10), p.1519-1529

1997

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Thalidomide increases both intra-tumoural tumour necrosis factor-α production and anti-tumour activity in response to 5,6-dimethylxanthenone-4-acetic acid

British journal of cancer, 1999-05, Vol.80 (5-6), p.716-723

1999

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Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid: concomitant reduction of serum tumour necrosis factor-alpha and enhancement of anti-tumour activity

British journal of cancer, 1998-08, Vol.78 (3), p.336-343

1998

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Tyrosine Kinase Inhibitors. 10. Isomeric 4-[(3-Bromophenyl)amino]pyrido[d]- pyrimidines Are Potent ATP Binding Site Inhibitors of the Tyrosine Kinase Function of the Epidermal Growth Factor Receptor

Journal of medicinal chemistry, 1996-04, Vol.39 (9), p.1823-1835

1996

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Exposure, Postexposure, and Density-Mediated Effects of Atrazine on Amphibians: Breaking down Net Effects into Their Parts

Environmental health perspectives, 2006-01, Vol.114 (1), p.46-50

2006

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Aquatic herbicide exposure increases salamander desiccation risk eight months later in a terrestrial environment

Environmental toxicology and chemistry, 2005-05, Vol.24 (5), p.1253-1258

2005

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The Effect of Age on the Phenotype and Function of Developing Thymocytes

Journal of comparative pathology, 2010, Vol.142, p.S45-S59

2010

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Effect of thalidomide on tumour necrosis factor production and anti-tumour activity induced by 5,6-dimethylxanthenone-4-acetic acid

British journal of cancer, 1995-08, Vol.72 (2), p.339-343

1995

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Structure−Activity Relationships for 1-Phenylbenzimidazoles as Selective ATP Site Inhibitors of the Platelet-Derived Growth Factor Receptor

Journal of medicinal chemistry, 1998-12, Vol.41 (27), p.5457-5465

1998

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Structure−Activity Relationships for 5-Substituted 1-Phenylbenzimidazoles as Selective Inhibitors of the Platelet-Derived Growth Factor Receptor

Journal of medicinal chemistry, 1999-07, Vol.42 (13), p.2373-2382

1999

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Multiple stressors and salamanders: effects of an herbicide, food limitation, and hydroperiod

Ecological applications, 2004-08, Vol.14 (4), p.1028-1040

2004

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Lethal and sublethal effects of atrazine, carbaryl, endosulfan, and octylphenol on the streamside salamander (Ambystoma barbouri)

Environmental toxicology and chemistry, 2003-10, Vol.22 (10), p.2385-2392

2003

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Mustard Prodrugs for Activation by Escherichia coli Nitroreductase in Gene-Directed Enzyme Prodrug Therapy

Journal of medicinal chemistry, 1997-04, Vol.40 (8), p.1270-1275

1997

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Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductase

Biochemical pharmacology, 1995-08, Vol.50 (5), p.609-618

1995

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An evolutionary perspective on the mechanisms of immunosenescence

Trends in immunology, 2009-07, Vol.30 (7), p.374-381

2009

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The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development

The Journal of experimental medicine, 2002-07, Vol.196 (2), p.163-171

2002

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Alligators provide evidence for the evolution of an archosaurian mode of oviparity

Biology of reproduction, 1992-01, Vol.46 (1), p.39-47

1992

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Synthesis and hypoxia-selective cytotoxicity of a 2-nitroimidazole mustard

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (13), p.1741-1744

1998

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Helicobacter pylori infection rates in duodenal ulcer patients in the United States may be lower than previously estimated

The American journal of gastroenterology, 1999-07, Vol.94 (7), p.1834-1840

1999

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Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide

Cancer chemotherapy and pharmacology, 2000, Vol.46 (2), p.135-141

2000

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Immune senescence: significance of the stromal microenvironment

Identification of human-selective analogues of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs

Comparative bioactivation of the novel anti‐tuberculosis agent PA‐824 in Mycobacteria and a subcellular fraction of human liver

Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[d]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor

Tyrosine Kinase Inhibitors. 11. Soluble Analogues of Pyrrolo- and Pyrazoloquinazolines as Epidermal Growth Factor Receptor Inhibitors: Synthesis, Biological Evaluation, and Modeling of the Mode of Binding

Thalidomide increases both intra-tumoural tumour necrosis factor-α production and anti-tumour activity in response to 5,6-dimethylxanthenone-4-acetic acid

Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid: concomitant reduction of serum tumour necrosis factor-alpha and enhancement of anti-tumour activity

Tyrosine Kinase Inhibitors. 10. Isomeric 4-[(3-Bromophenyl)amino]pyrido[d]- pyrimidines Are Potent ATP Binding Site Inhibitors of the Tyrosine Kinase Function of the Epidermal Growth Factor Receptor

Exposure, Postexposure, and Density-Mediated Effects of Atrazine on Amphibians: Breaking down Net Effects into Their Parts

Aquatic herbicide exposure increases salamander desiccation risk eight months later in a terrestrial environment

The Effect of Age on the Phenotype and Function of Developing Thymocytes

Effect of thalidomide on tumour necrosis factor production and anti-tumour activity induced by 5,6-dimethylxanthenone-4-acetic acid

Structure−Activity Relationships for 1-Phenylbenzimidazoles as Selective ATP Site Inhibitors of the Platelet-Derived Growth Factor Receptor

Structure−Activity Relationships for 5-Substituted 1-Phenylbenzimidazoles as Selective Inhibitors of the Platelet-Derived Growth Factor Receptor

Multiple stressors and salamanders: effects of an herbicide, food limitation, and hydroperiod

Lethal and sublethal effects of atrazine, carbaryl, endosulfan, and octylphenol on the streamside salamander (Ambystoma barbouri)

Mustard Prodrugs for Activation by Escherichia coli Nitroreductase in Gene-Directed Enzyme Prodrug Therapy

Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductase

An evolutionary perspective on the mechanisms of immunosenescence

The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development

Alligators provide evidence for the evolution of an archosaurian mode of oviparity

Synthesis and hypoxia-selective cytotoxicity of a 2-nitroimidazole mustard

Helicobacter pylori infection rates in duodenal ulcer patients in the United States may be lower than previously estimated

Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide

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