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Manufacturing of recombinant adeno-associated viral vectors: new technologies are welcome

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.15049-15049, Article 15049

Ayuso, Eduard

2016

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Pharmacology of Recombinant Adeno-associated Virus Production

Molecular therapy. Methods & clinical development, 2018-03, Vol.8 (C), p.166-180

2018

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Genetic variability of human adenovirus type 7 circulating in mainland China

PloS one, 2020-04, Vol.15 (4), p.e0232092-e0232092

2020

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Phylogenetic and genome-wide deep-sequencing analyses of canine parvovirus reveal co-infection with field variants and emergence of a recent recombinant strain

PloS one, 2014-11, Vol.9 (11), p.e111779-e111779

2014

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Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates

Science translational medicine, 2019-05, Vol.11 (493)

2019

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Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity

PloS one, 2015-02, Vol.10 (2), p.e0115350-e0115350

2015

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Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates

Nature communications, 2022-05, Vol.13 (1), p.2454-2454, Article 2454

2022

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Production, purification and characterization of adeno-associated vectors

Current gene therapy, 2010-12, Vol.10 (6), p.423-436

2010

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Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy

The Journal of clinical investigation, 2013-08, Vol.123 (8), p.3254-3271

2013

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Nitrogen Gas Plasma Generated by a Static Induction Thyristor as a Pulsed Power Supply Inactivates Adenovirus

PloS one, 2016-06, Vol.11 (6), p.e0157922

2016

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Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs

PloS one, 2014-02, Vol.9 (2), p.e88124-e88124

2014

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Induction of Immune Tolerance to Foreign Protein via Adeno-Associated Viral Vector Gene Transfer in Mid-Gestation Fetal Sheep

PloS one, 2017-01, Vol.12 (1), p.e0171132-e0171132

2017

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Correction of pathological accumulation of glycosaminoglycans in central nervous system and peripheral tissues of MPSIIIA mice through systemic AAV9 gene transfer

Human gene therapy, 2012-12, Vol.23 (12), p.1237-1246

2012

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Generation of infectious recombinant Adeno-associated virus in Saccharomyces cerevisiae

PloS one, 2017-03, Vol.12 (3), p.e0173010-e0173010

2017

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Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

PloS one, 2010-01, Vol.5 (1), p.e8771-e8771

2010

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Stability of the adeno-associated virus 8 reference standard material

Gene therapy, 2019-05, Vol.26 (5), p.211-215

2019

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Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina

Biomedicine & pharmacotherapy, 2024-02, Vol.171, p.116148-116148, Article 116148

2024

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Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression

Cardiovascular research, 2009-09, Vol.83 (4), p.663-671

2009

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Characterization of residual microRNAs in AAV vector batches produced in HEK293 mammalian cells and Sf9 insect cells

Molecular therapy. Methods & clinical development, 2024-09, Vol.32 (3), p.101305, Article 101305

2024

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Treatment of Diabetes and Long-Term Survival After Insulin and Glucokinase Gene Therapy

Diabetes (New York, N.Y.), 2013-05, Vol.62 (5), p.1718-1729

2013

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Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells

PloS one, 2015-12, Vol.10 (12), p.e0145116-e0145116

2015

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Practical utilization of recombinant AAV vector reference standards: focus on vector genomes titration by free ITR qPCR

Molecular therapy. Methods & clinical development, 2016-01, Vol.5 (C), p.16019-16019, Article 16019

2016

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Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

Molecular therapy. Methods & clinical development, 2018-09, Vol.10, p.223-236

2018

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Generation of Ugt1-deficient murine liver cell lines using TALEN technology

PloS one, 2014-08, Vol.9 (8), p.e104816

2014

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Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue

PloS one, 2015-12, Vol.10 (12), p.e0144606-e0144606

2015

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Manufacturing of recombinant adeno-associated viral vectors: new technologies are welcome

Pharmacology of Recombinant Adeno-associated Virus Production

Genetic variability of human adenovirus type 7 circulating in mainland China

Phylogenetic and genome-wide deep-sequencing analyses of canine parvovirus reveal co-infection with field variants and emergence of a recent recombinant strain

Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates

Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity

Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates

Production, purification and characterization of adeno-associated vectors

Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy

Nitrogen Gas Plasma Generated by a Static Induction Thyristor as a Pulsed Power Supply Inactivates Adenovirus

Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs

Induction of Immune Tolerance to Foreign Protein via Adeno-Associated Viral Vector Gene Transfer in Mid-Gestation Fetal Sheep

Correction of pathological accumulation of glycosaminoglycans in central nervous system and peripheral tissues of MPSIIIA mice through systemic AAV9 gene transfer

Generation of infectious recombinant Adeno-associated virus in Saccharomyces cerevisiae

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

Stability of the adeno-associated virus 8 reference standard material

Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression

Characterization of residual microRNAs in AAV vector batches produced in HEK293 mammalian cells and Sf9 insect cells

Treatment of Diabetes and Long-Term Survival After Insulin and Glucokinase Gene Therapy

Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells

Practical utilization of recombinant AAV vector reference standards: focus on vector genomes titration by free ITR qPCR

Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

Generation of Ugt1-deficient murine liver cell lines using TALEN technology

Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue

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