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PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (27), p.13394-13403

2019

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STIM2 (Stromal Interaction Molecule 2)–Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension

Hypertension (Dallas, Tex. 1979), 2018-03, Vol.71 (3), p.518-529

2018

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Editorial: Calcium regulation and Mechano-transduction in vascular diseases: obligatory role of transient receptor potential and Piezo channels

Frontiers in physiology, 2024-02, Vol.15, p.1375432-1375432

2024

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Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2019-01, Vol.316 (1), p.L216-L228

2019

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Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2016-05, Vol.310 (9), p.L846-L859

2016

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MicroRNA-mediated downregulation of K + channels in pulmonary arterial hypertension

American journal of physiology. Lung cellular and molecular physiology, 2020-01, Vol.318 (1), p.L10-L26

2020

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Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

JACC. Basic to translational science, 2018-12, Vol.3 (6), p.744-762

2018

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p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle

Frontiers in physiology, 2023-09, Vol.14, p.1228488-1228488

2023

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Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series)

Pulmonary circulation, 2018-01, Vol.8 (1), p.1-17

2018

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Calcium-Sensing Receptor Regulates Cytosolic [Ca 2+ ] and Plays a Major Role in the Development of Pulmonary Hypertension

Frontiers in physiology, 2016-11, Vol.7, p.517-517

2016

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Revisiting the Role of KCNA5 in Pulmonary Arterial Hypertension

American journal of respiratory cell and molecular biology, 2023-08, Vol.69 (2), p.123-125

2023

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Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension

Pulmonary circulation, 2020-07, Vol.10 (3), p.1-15

2020

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Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes

Pulmonary circulation, 2020-10, Vol.10 (4), p.1-5

2020

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Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension

American Journal of Physiology: Cell Physiology, 2021-12, Vol.321 (6), p.C1010-C1027

2021

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Molecular and functional significance of Ca2+-activated Cl− channels in pulmonary arterial smooth muscle

Pulmonary Circulation, 2015-06, Vol.5 (2), p.244-268

2015

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Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia‐induced pulmonary hypertension

British journal of pharmacology, 2017-11, Vol.174 (22), p.4155-4172

2017

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Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels

American Journal of Physiology: Cell Physiology, 2020-05, Vol.318 (5), p.C954-C968

2020

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Hypoxia selectively upregulates cation channels and increases cytosolic [Ca 2+ ] in pulmonary, but not coronary, arterial smooth muscle cells

American Journal of Physiology: Cell Physiology, 2018-04, Vol.314 (4), p.C504-C517

2018

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Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

American Journal of Physiology: Cell Physiology, 2014-08, Vol.307 (4), p.C373-C383

2014

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Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension

American Journal of Physiology: Cell Physiology, 2012-12, Vol.303 (12), p.C1229-C1243

2012

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Molecular mechanism of TMEM16A regulation: role of CaMKII and PP1/PP2A

American Journal of Physiology: Cell Physiology, 2019-12, Vol.317 (6), p.C1093-C1106

2019

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Ryanodine receptor-2: a necessity for gating store-operated Ca2+ channels

Cardiovascular research, 2016-07, Vol.111 (1), p.13-15

2016

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Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH

American journal of physiology. Lung cellular and molecular physiology, 2017-03, Vol.312 (3), p.L309-L325

2017

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Notch enhances Ca 2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K + channels

American Journal of Physiology: Cell Physiology, 2020-05, Vol.318 (5), p.C954-C968

2020

Volltextzugriff (PDF)

New insights into the pathology of pulmonary hypertension: implication of the miR‐210/ISCU1/2/Fe‐S axis

EMBO molecular medicine, 2015-06, Vol.7 (6), p.689-691

2015

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PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension

STIM2 (Stromal Interaction Molecule 2)–Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension

Editorial: Calcium regulation and Mechano-transduction in vascular diseases: obligatory role of transient receptor potential and Piezo channels

Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension

Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension

MicroRNA-mediated downregulation of K + channels in pulmonary arterial hypertension

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle

Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series)

Calcium-Sensing Receptor Regulates Cytosolic [Ca 2+ ] and Plays a Major Role in the Development of Pulmonary Hypertension

Revisiting the Role of KCNA5 in Pulmonary Arterial Hypertension

Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension

Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes

Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension

Molecular and functional significance of Ca2+-activated Cl− channels in pulmonary arterial smooth muscle

Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia‐induced pulmonary hypertension

Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels

Hypoxia selectively upregulates cation channels and increases cytosolic [Ca 2+ ] in pulmonary, but not coronary, arterial smooth muscle cells

Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension

Molecular mechanism of TMEM16A regulation: role of CaMKII and PP1/PP2A

Ryanodine receptor-2: a necessity for gating store-operated Ca2+ channels

Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH

Notch enhances Ca 2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K + channels

New insights into the pathology of pulmonary hypertension: implication of the miR‐210/ISCU1/2/Fe‐S axis

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