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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10732-10737

2014

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Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

Acta neuropathologica, 2016-01, Vol.131 (1), p.103-114

2016

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Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection

PloS one, 2020-01, Vol.15 (1), p.e0227655

2020

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Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts

Journal of virology, 2018-09, Vol.92 (18)

2018

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Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice

Viruses, 2023-08, Vol.15 (9), p.1819

2023

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Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS

Acta neuropathologica, 2016-12, Vol.132 (6), p.827-840

2016

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The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

PLoS pathogens, 2011-03, Vol.7 (3), p.e1001317

2011

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Expanding spectrum of prion diseases

Emerging topics in life sciences, 2020-09, Vol.4 (2), p.155-167

2020

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The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease

PLoS pathogens, 2011-03, Vol.7 (3), p.e1001317-e1001317

2011

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Loss of charge mutations in solvent exposed Lys residues of superoxide dismutase 1 do not induce inclusion formation in cultured cell models

PloS one, 2018-11, Vol.13 (11), p.e0206751-e0206751

2018

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Coinfecting Prion Strains Compete for a Limiting Cellular Resource

Journal of Virology, 2010-06, Vol.84 (11), p.5706-5714

2010

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Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence

Acta neuropathologica communications, 2021-05, Vol.9 (1), p.92-92, Article 92

2021

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Experimental Mutations in Superoxide Dismutase 1 Provide Insight into Potential Mechanisms Involved in Aberrant Aggregation in Familial Amyotrophic Lateral Sclerosis

G3 : genes - genomes - genetics, 2019-03, Vol.9 (3), p.719-728

2019

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Prion-like Spreading in Tauopathies

Biological psychiatry (1969), 2018-02, Vol.83 (4), p.337-346

2018

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ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons

iScience, 2019-01, Vol.11, p.294-304

2019

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Phenotypic diversity in ALS and the role of poly-conformational protein misfolding

Acta neuropathologica, 2021-07, Vol.142 (1), p.41-55

2021

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Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (6), p.1

2022

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Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases

Acta neuropathologica communications, 2014-05, Vol.2 (1), p.55-55, Article 55

2014

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Prion Strain Targeting Independent of Strain-Specific Neuronal Tropism

Journal of Virology, 2009-01, Vol.83 (1), p.81-87

2009

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Prion protein - mediator of toxicity in multiple proteinopathies

Nature reviews. Neurology, 2020-04, Vol.16 (4), p.187

2020

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ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons

iScience, 2019-09, Vol.19, p.448-449

2019

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Experimental transmissibility of mutant SOD1 motor neuron disease

Acta neuropathologica, 2014-12, Vol.128 (6), p.791-803

2014

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Prion Interference Is Due to a Reduction in Strain-Specific PrPSc Levels

Journal of Virology, 2007-01, Vol.81 (2), p.689-697

2007

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Novel SOD1 monoclonal antibodies against the electrostatic loop preferentially detect misfolded SOD1 aggregates

Neuroscience letters, 2021-01, Vol.742, p.135553-135553, Article 135553

2021

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Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils

Journal of virology, 2017-01, Vol.91 (2)

2017

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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice

Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection

Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts

Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice

Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS

The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

Expanding spectrum of prion diseases

The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease

Loss of charge mutations in solvent exposed Lys residues of superoxide dismutase 1 do not induce inclusion formation in cultured cell models

Coinfecting Prion Strains Compete for a Limiting Cellular Resource

Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence

Experimental Mutations in Superoxide Dismutase 1 Provide Insight into Potential Mechanisms Involved in Aberrant Aggregation in Familial Amyotrophic Lateral Sclerosis

Prion-like Spreading in Tauopathies

ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons

Phenotypic diversity in ALS and the role of poly-conformational protein misfolding

Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy

Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases

Prion Strain Targeting Independent of Strain-Specific Neuronal Tropism

Prion protein - mediator of toxicity in multiple proteinopathies

ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons

Experimental transmissibility of mutant SOD1 motor neuron disease

Prion Interference Is Due to a Reduction in Strain-Specific PrPSc Levels

Novel SOD1 monoclonal antibodies against the electrostatic loop preferentially detect misfolded SOD1 aggregates

Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils

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