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The new normal: immunomodulatory agents against sepsis immune suppression

Trends in molecular medicine, 2014-04, Vol.20 (4), p.224-233

2014

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The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients

Clinics in chest medicine, 2008-12, Vol.29 (4), p.617-625

2008

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PAD4 Deficiency Leads to Decreased Organ Dysfunction and Improved Survival in a Dual Insult Model of Hemorrhagic Shock and Sepsis

The Journal of immunology (1950), 2018-03, Vol.200 (5), p.1817-1828

2018

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PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (15), p.6303-6308

2009

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Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model

Journal of innate immunity, 2017-01, Vol.9 (1), p.22-32

2017

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Part II: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Types of Infections and Organ Dysfunction Endpoints

Shock (Augusta, Ga.), 2019-01, Vol.51 (1), p.23-32

2019

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Biomarkers for Sepsis: What Is and What Might Be?

Biomarker Insights, 2015-01, Vol.2015 (Suppl. 4), p.7-17

2015

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Identification of B7-H1 as a novel mediator of the innate immune/proinflammatory response as well as a possible myeloid cell prognostic biomarker in sepsis

The Journal of immunology (1950), 2014-02, Vol.192 (3), p.1091-1099

2014

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The Neonatal Innate Immune Response to Sepsis: Checkpoint Proteins as Novel Mediators of This Response and as Possible Therapeutic/Diagnostic Levers

Frontiers in immunology, 2022-07, Vol.13, p.940930-940930

2022

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Novel Role for PD-1:PD-L1 as Mediator of Pulmonary Vascular Endothelial Cell Functions in Pathogenesis of Indirect ARDS in Mice

Frontiers in immunology, 2018-12, Vol.9, p.3030

2018

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Kupffer Cells Protect Liver Sinusoidal Endothelial Cells from Fas-Dependent Apoptosis in Sepsis by Down-Regulating gp130

The American journal of pathology, 2013-03, Vol.182 (3), p.742-754

2013

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Regulatory T cell populations in sepsis and trauma

Journal of leukocyte biology, 2008-03, Vol.83 (3), p.523-535

2008

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Herpes virus entry mediator signaling blockade produces mortality in neonatal sepsis through induced cardiac dysfunction

Frontiers in immunology, 2024-05, Vol.15, p.1365174-1365174

2024

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SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model

Molecular medicine (Cambridge, Mass.), 2020-09, Vol.26 (1), p.89-89, Article 89

2020

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Improved survival after induction of sepsis by cecal slurry in PD-1 knockout murine neonates

Surgery, 2017-05, Vol.161 (5), p.1387-1393

2017

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Pathogenesis of indirect (secondary) acute lung injury

Expert review of respiratory medicine, 2011-02, Vol.5 (1), p.115-126

2011

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Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD‐1

Journal of leukocyte biology, 2014-11, Vol.96 (5), p.809-820

2014

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BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction

Journal of leukocyte biology, 2012-09, Vol.92 (3), p.593-603

2012

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Kupffer cells potentiate liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1

Journal of leukocyte biology, 2013-11, Vol.94 (5), p.963-970

2013

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Neutrophil-endothelial interactions mediate angiopoietin-2-associated pulmonary endothelial cell dysfunction in indirect acute lung injury in mice

American journal of respiratory cell and molecular biology, 2014-01, Vol.50 (1), p.193-200

2014

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Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

Frontiers in immunology, 2022-03, Vol.13, p.861670-861670

2022

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Leukocyte apoptosis and its significance in sepsis and shock

Journal of leukocyte biology, 2005-08, Vol.78 (2), p.325-337

2005

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Deep RNA sequencing of intensive care unit patients with COVID-19

Scientific reports, 2022-09, Vol.12 (1), p.15755-10, Article 15755

2022

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NLRP3 inflammasome activation in cigarette smoke priming for Pseudomonas aeruginosa-induced acute lung injury

Redox biology, 2022-11, Vol.57, p.102467, Article 102467

2022

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Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

Frontiers in immunology, 2020-03, Vol.11, p.264-264

2020

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The new normal: immunomodulatory agents against sepsis immune suppression

The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients

PAD4 Deficiency Leads to Decreased Organ Dysfunction and Improved Survival in a Dual Insult Model of Hemorrhagic Shock and Sepsis

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model

Part II: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Types of Infections and Organ Dysfunction Endpoints

Biomarkers for Sepsis: What Is and What Might Be?

Identification of B7-H1 as a novel mediator of the innate immune/proinflammatory response as well as a possible myeloid cell prognostic biomarker in sepsis

The Neonatal Innate Immune Response to Sepsis: Checkpoint Proteins as Novel Mediators of This Response and as Possible Therapeutic/Diagnostic Levers

Novel Role for PD-1:PD-L1 as Mediator of Pulmonary Vascular Endothelial Cell Functions in Pathogenesis of Indirect ARDS in Mice

Kupffer Cells Protect Liver Sinusoidal Endothelial Cells from Fas-Dependent Apoptosis in Sepsis by Down-Regulating gp130

Regulatory T cell populations in sepsis and trauma

Herpes virus entry mediator signaling blockade produces mortality in neonatal sepsis through induced cardiac dysfunction

SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model

Improved survival after induction of sepsis by cecal slurry in PD-1 knockout murine neonates

Pathogenesis of indirect (secondary) acute lung injury

Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD‐1

BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction

Kupffer cells potentiate liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1

Neutrophil-endothelial interactions mediate angiopoietin-2-associated pulmonary endothelial cell dysfunction in indirect acute lung injury in mice

Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

Leukocyte apoptosis and its significance in sepsis and shock

Deep RNA sequencing of intensive care unit patients with COVID-19

NLRP3 inflammasome activation in cigarette smoke priming for Pseudomonas aeruginosa-induced acute lung injury

Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

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