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Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update

Physiological reviews, 2012-04, Vol.92 (2), p.689-737

2012

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MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

Current biology, 2008-03, Vol.18 (5), p.311-321

2008

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Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation

The Journal of biological chemistry, 2019-08, Vol.294 (31), p.11944-11951

2019

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Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (49), p.E1312-E1320

2011

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YAP oncogene overexpression supercharges colon cancer proliferation

Cell cycle (Georgetown, Tex.), 2012-03, Vol.11 (6), p.1090-1096

2012

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Amino acid regulation of TOR complex 1

American journal of physiology: endocrinology and metabolism, 2009-04, Vol.296 (4), p.E592-E602

2009

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Amino Acids Activate Mammalian Target of Rapamycin (mTOR) Complex 1 without Changing Rag GTPase Guanyl Nucleotide Charging

The Journal of biological chemistry, 2014-01, Vol.289 (5), p.2658-2674

2014

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Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

Cancer cell, 2009-11, Vol.16 (5), p.425-438

2009

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Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

Physiological reviews, 2001-04, Vol.81 (2), p.807-869

2001

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Protein kinases of the Hippo pathway: Regulation and substrates

Seminars in cell & developmental biology, 2012-09, Vol.23 (7), p.770-784

2012

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14-3-3 Proteins: Active Cofactors in Cellular Regulation by Serine/Threonine Phosphorylation

The Journal of biological chemistry, 2002-02, Vol.277 (5), p.3061-3064

2002

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mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry

Genes & development, 2011-06, Vol.25 (11), p.1159-1172

2011

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The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes

The Journal of experimental medicine, 2012-04, Vol.209 (4), p.741-759

2012

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IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1

eLife, 2017-07, Vol.6

2017

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IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

Cell metabolism, 2015-04, Vol.21 (4), p.609-621

2015

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RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression

Molecular metabolism (Germany), 2021-06, Vol.48, p.101209-101209, Article 101209

2021

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Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk

Nature communications, 2019-05, Vol.10 (1), p.2078-2078, Article 2078

2019

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Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

Gastroenterology (New York, N.Y. 1943), 2013-06, Vol.144 (7), p.1543-1553.e1

2013

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Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

Biochemical journal, 2004-07, Vol.381 (Pt 2), p.453-462

2004

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Glutamatergic Regulation of the p70S6 Kinase in Primary Mouse Neurons

The Journal of biological chemistry, 2005-11, Vol.280 (46), p.38121-38124

2005

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YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

Cell reports (Cambridge), 2015-03, Vol.10 (10), p.1692-1707

2015

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Proof-of-concept, randomized, controlled clinical trial of Bacillus-Calmette-Guerin for treatment of long-term type 1 diabetes

PloS one, 2012-08, Vol.7 (8), p.e41756-e41756

2012

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MAP kinase pathways: The first twenty years

Biochimica et biophysica acta, 2007-08, Vol.1773 (8), p.1150-1160

Avruch, Joseph

2007

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Rheb Binding to Mammalian Target of Rapamycin (mTOR) Is Regulated by Amino Acid Sufficiency

The Journal of biological chemistry, 2005-06, Vol.280 (25), p.23433-23436

2005

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Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action

Cell, 2002-07, Vol.110 (2), p.177-189

2002

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Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update

MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

YAP oncogene overexpression supercharges colon cancer proliferation

Amino acid regulation of TOR complex 1

Amino Acids Activate Mammalian Target of Rapamycin (mTOR) Complex 1 without Changing Rag GTPase Guanyl Nucleotide Charging

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

Protein kinases of the Hippo pathway: Regulation and substrates

14-3-3 Proteins: Active Cofactors in Cellular Regulation by Serine/Threonine Phosphorylation

mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes

IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression

Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk

Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

Glutamatergic Regulation of the p70S6 Kinase in Primary Mouse Neurons

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

Proof-of-concept, randomized, controlled clinical trial of Bacillus-Calmette-Guerin for treatment of long-term type 1 diabetes

MAP kinase pathways: The first twenty years

Rheb Binding to Mammalian Target of Rapamycin (mTOR) Is Regulated by Amino Acid Sufficiency

Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action

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